International Chemical Safety Cards 2,4-XYLIDINE ICSC: 1562 2,4-Dimethylbenzeneamine 4-Aminodimethylbenzene 2-Methyl-p-toluidine C8H11N Molecular mass: 121.18 ICSC #    1562 CAS #     95-68-1 RTECS # ZE8575000 UN #        1711 EC #         612-027-00-0 October 25, 2004 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames. Water spray, carbon dioxide , foam , powder . EXPLOSION Above 90°C explosive vapour/air mixtures may be formed. Above 90°C use a closed system, ventilation. EXPOSURE  •INHALATION Blue lips or finger nails. Dizziness. Headache. Nausea. Confusion. Ventilation, local exhaust, or breathing protection. Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.  •SKIN MAY BE ABSORBED! Redness. Protective gloves. Protective clothing. Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.  •EYES Redness. Pain. Safety goggles, or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION (See Inhalation). Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Give a slurry of activated charcoal in water to drink. Rest. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT let this chemical enter the environment. Personal protection: filter respirator for organic gases and vapours. Chemical protection suit. Well closed. Separated from strong oxidants, hypochlorites, food and feedstuffs . Do not transport with food and feedstuffs. Note: C T symbol N symbol R: 23/24/25-33-51/53 S: 1/2-28-36/37-45-61 UN Hazard Class: 6.1 UN Packing Group: II SEE IMPORTANT INFORMATION ON BACK ICSC: 1562 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards 2,4-XYLIDINE ICSC: 1562 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: YELLOW LIQUID , WITH CHARACTERISTIC ODOUR. TURNS BROWN ON EXPOSURE TO AIR. PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on burning producing toxic and corrosive fumes. Reacts violently with strong oxidants. Reacts with hypochlorites forming explosive chloroamines. Attacks plasticandrubber. OCCUPATIONAL EXPOSURE LIMITS: TLV: 0.5 ppm as TWA; (skin); A3; (ACGIH 2004). MAK: H; Carcinogen category: 2; (DFG 2004). ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation, through the skin and by ingestion. INHALATION RISK: A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster. EFFECTS OF SHORT-TERM EXPOSURE: The substance is irritating to the eyes , the skin and the respiratory tract . Exposure at high levels may result in the formation of methaemoglobin. The effects may be delayed. Medical observation is indicated. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: The substance may have effects on the blood , resulting in anaemia . The substance may have effects on the kidneys and liver . PHYSICAL PROPERTIES Boiling point: 214°C Melting point: -14°C Density: 0.98 g/cm³ Solubility in water, g/100 ml at 20°C: 34 Vapour pressure, Pa at 20°C: 10 Relative vapour density (air = 1): 4.2 Flash point: 90°C c.c. Auto-ignition temperature: 520°C Explosive limits, vol% in air: 1.10-7.0 Octanol/water partition coefficient as log Pow: 1.68-2.13 ENVIRONMENTAL DATA The substance is harmful to aquatic organisms. N O T E S Depending on the degree of exposure, periodic medical examination is suggested. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. See ICSC 0600 Xylidine (mixed isomers). Transport Emergency Card: TEC (R)-61S1711-L NFPA Code: H3; F1; R0; ADDITIONAL INFORMATION ICSC: 1562 2,4-XYLIDINE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.