International Chemical Safety Cards SPINOSAD ICSC: 1502 C41H65NO10 x C42H67NO10 ICSC #    1502 CAS #     168316-95-8 RTECS # WG9110000 April 22, 2004 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames. Powder, water spray, foam, carbon dioxide. EXPLOSION EXPOSURE  •INHALATION Avoid inhalation of dust .  •SKIN Protective gloves.  •EYES Redness. Pain. Safety spectacles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Do not eat, drink, or smoke during work. Wash hands before eating. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Sweep spilled substance into containers. Do NOT let this chemical enter the environment. Personal protection: P1 filter respirator for inert particles. Separated from food and feedstuffs. Do not transport with food and feedstuffs. R: S: SEE IMPORTANT INFORMATION ON BACK ICSC: 1502 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards SPINOSAD ICSC: 1502 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: GREY TO WHITE SOLID PHYSICAL DANGERS: CHEMICAL DANGERS: OCCUPATIONAL EXPOSURE LIMITS: TLV not established. MAK not established. ROUTES OF EXPOSURE: The substance can be absorbed into the body by ingestion. INHALATION RISK: Evaporation at 20°C is negligible; a nuisance-causing concentration of airborne particles can, however, be reached quickly on spraying or when dispersed, especially if powdered. EFFECTS OF SHORT-TERM EXPOSURE: The substance is mildly irritating to the eyes. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: The substance may have effects on the kidneys and liver , resulting in tissue lesions . PHYSICAL PROPERTIES Boiling point (decomposes): 173°C Melting point: 112-123°C Solubility in water: none Vapour pressure, Pa at 20°C: negligible Octanol/water partition coefficient as log Pow: 4 ENVIRONMENTAL DATA The substance is harmful to aquatic organisms. This substance may be hazardous in the environment; special attention should be given to honey bees. This substance does enter the environment under normal use. Great care, however, should be given to avoid any additional release, e.g. through inappropriate disposal. N O T E S Spinosad is a mixture of Spinosyn A (CAS 131929-60-7) and Spinosyn B (CAS 131929-63-0). If the substance is formulated with solvents also consult the ICSCs of these materials. Carrier solvents used in commercial formulations may change physical and toxicological properties. ADDITIONAL INFORMATION ICSC: 1502 SPINOSAD (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.