International Chemical Safety Cards TRIMETHYLAMINE (40% aqueous solution) ICSC: 1484 N,N-Dimethylmethanamine TMA C3H9N / (CH3)3N Molecular mass: 59.1 ICSC #    1484 CAS #     75-50-3 RTECS # PA0350000 UN #        1297 EC #         612-001-01-6 May 06, 2003 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Extremely flammable. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames, NO sparks, and NO smoking. Water in large amounts, alcohol-resistant foam, dry powder, carbon dioxide. EXPLOSION Vapour/air mixtures are explosive. Closed system, ventilation, explosion-proof electrical equipment and lighting. Use non-sparking handtools. In case of fire: keep drums, etc., cool by spraying with water. EXPOSURE AVOID ALL CONTACT!  •INHALATION Burning sensation. Cough. Headache. Sore throat. Laboured breathing. Shortness of breath. Ventilation, local exhaust, or breathing protection. Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.  •SKIN Redness. Pain. Skin burns. Protective gloves. Protective clothing. Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention.  •EYES Redness. Pain. Blurred vision. Severe deep burns. Face shield, or or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Abdominal pain. Burning sensation. Shock or collapse. Do not eat, drink, or smoke during work. Rinse mouth. Do NOT induce vomiting. Give plenty of water to drink. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Evacuate danger area! Consult an expert! Ventilation. Remove all ignition sources. Remove vapour with fine water spray. Personal protection: complete protective clothing including self-contained breathing apparatus. Fireproof. Well closed. Separated from strong acids, oxidants , aluminium , copper , zinc and their alloys, and mercury. Do not transport with food and feedstuffs. Note: B F+ symbol C symbol R: 12-20/22-34 S: 1/2-3-16-26-29-36/37/39-45 UN Hazard Class: 3 UN Subsidiary Risks: 8 UN Packing Group: I SEE IMPORTANT INFORMATION ON BACK ICSC: 1484 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards TRIMETHYLAMINE (40% aqueous solution) ICSC: 1484 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS SOLUTION IN WATER , WITH PUNGENT ODOUR. PHYSICAL DANGERS: The vapour is heavier than air and may travel along the ground; distant ignition possible. CHEMICAL DANGERS: The substance is a medium strong base. Reacts violently with mercury and oxidants causing fire and explosion hazard. Attacks metals such asaluminium,copper,zinc, tin, and their alloys. OCCUPATIONAL EXPOSURE LIMITS: TLV: 5 ppm as TWA, 15 ppm as STEL; (ACGIH 2004). MAK: 2 ppm, 4.9 mg/m³; Peak limitation category: I(2); Pregnancy risk group: D; (DFG 2004). ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its vapour and by ingestion. INHALATION RISK: A harmful contamination of the air will on evaporation of this substance at 20°C be reached very quickly. EFFECTS OF SHORT-TERM EXPOSURE: The substance is corrosive to the eyes and the skin. The vapour is severely irritating to the respiratory tract . Corrosive on ingestion. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: PHYSICAL PROPERTIES Boiling point: 30°C Melting point: -3°C Relative density (water = 1): 0.9 Vapour pressure, kPa at 20°C: 67 Relative vapour density (air = 1): 2.0 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.6 Flash point: -7°C Auto-ignition temperature: 190°C Explosive limits, vol% in air: 2-16.6 Octanol/water partition coefficient as log Pow: -0.3 ENVIRONMENTAL DATA N O T E S The toxicological data apply to solutions containing over 15% of trimethylamine. See ICSC 0206 Trimethylamine gas in a cylinder. Card has been partly updated in April 2005. See sections Occupational Exposure Limits, EU classification. Transport Emergency Card: TEC (R)-30S1279-I NFPA Code: H3; F4; R0 ADDITIONAL INFORMATION ICSC: 1484 TRIMETHYLAMINE (40% aqueous solution) (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.