International Chemical Safety Cards 1-VINYL-2-PYRROLIDONE ICSC: 1478 Vinylbutyrolactam 1-Ethenylpyrrolidin-2-one N-Vinyl-2-pyrrolidinone C6H9NO Molecular mass: 111.14 ICSC #    1478 CAS #     88-12-0 RTECS # UY6107000 EC #         613-168-00-0 April 21, 2004 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. NO open flames. Powder, water spray, foam, carbon dioxide. EXPLOSION EXPOSURE STRICT HYGIENE!  •INHALATION Cough. Sore throat. Ventilation, local exhaust, or breathing protection. Fresh air, rest. Refer for medical attention.  •SKIN Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.  •EYES Redness. Pain. Severe deep burns. Safety goggles or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Abdominal pain. Diarrhoea. Nausea. Vomiting. Do not eat, drink, or smoke during work. Rinse mouth. Give plenty of water to drink. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Personal protection: filter respirator for organic gases and vapours. Separated from strong acids. Keep in the dark. Cool. Store only if stabilized. Note: D Xn symbol R: 20/21/22-37-40-41-48/20 S: 26-36/37/39 SEE IMPORTANT INFORMATION ON BACK ICSC: 1478 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards 1-VINYL-2-PYRROLIDONE ICSC: 1478 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS TO YELLOW LIQUID PHYSICAL DANGERS: CHEMICAL DANGERS: The substance may polymerize in the presence of air due to warming, under the influence of light and acid(s). The substance decomposes on burning producing toxic and corrosive gases(nitrogen oxides). OCCUPATIONAL EXPOSURE LIMITS: TLV: 0.05 ppm as TWA; A3 (confirmed animal carcinogen with unknown relevance to humans); (ACGIH 2004). MAK: skin absorption (H); Carcinogen category: 2; (DFG 2004). ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation, through the skin and by ingestion. INHALATION RISK: A harmful contamination of the air will be reached quickly on evaporation of this substance at 20°C. EFFECTS OF SHORT-TERM EXPOSURE: The substance is irritating to the respiratory tract and is corrosive to the eyes. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: The substance may have effects on the liver , resulting in liver impairment. Tumours have been detected in experimental animals but may not be relevant to humans. PHYSICAL PROPERTIES Boiling point at 1.3 kPa: 90-93°C Melting point: 13°C Relative density (water = 1): 1.04 Solubility in water: very good Vapour pressure, Pa at 20°C: 12 Relative vapour density (air = 1): 3.83 Flash point: 93°C Auto-ignition temperature: 364°C Explosive limits, vol% in air: 1.4-10 Octanol/water partition coefficient as log Pow: 0.4 ENVIRONMENTAL DATA N O T E S Depending on the degree of exposure, periodic medical examination is suggested. Card has been partly updated in April 2005. See section Occupational Exposure Limits. NFPA Code: H0; F1; R0; ADDITIONAL INFORMATION ICSC: 1478 1-VINYL-2-PYRROLIDONE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.