International Chemical Safety Cards n-BUTYRONITRILE ICSC: 1465 Butanenitrile Butyric acid nitrile 1-Cyanopropane n-Propyl cyanide C4H7N / CH3CH2CH2CN Molecular mass: 69.1 ICSC #    1465 CAS #     109-74-0 RTECS # ET8750000 UN #        2411 EC #         608-005-00-5 May 06, 2003 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Highly flammable. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames, NO sparks, and NO smoking. NO contact with oxidants. Water spray, foam, alcohol-resistant foam, dry powder, carbon dioxide. EXPLOSION Above 17°C explosive vapour/air mixtures may be formed. Above 17°C use a closed system, ventilation, and explosion-proof electrical equipment. Do NOT use compressed air for filling, discharging, or handling. In case of fire: keep drums, etc., cool by spraying with water. EXPOSURE STRICT HYGIENE! IN ALL CASES CONSULT A DOCTOR!  •INHALATION Dizziness. Laboured breathing. Nausea. Vomiting. Weakness. Confusion. Convulsions. Unconsciousness. Ventilation, local exhaust, or breathing protection. Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention. See Notes.  •SKIN MAY BE ABSORBED! Redness. (Further see Inhalation). Protective clothing. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.  •EYES Redness. Pain. Blurred vision. Face shield, or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION (See Inhalation). Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Give a slurry of activated charcoal in water to drink. Refer for medical attention. See Notes. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Remove all ignition sources. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT let this chemical enter the environment. (Extra personal protection: self-contained breathing apparatus.) Fireproof. Separated from strong oxidants, strong reducing agents , strong bases , strong acids, food and feedstuffs . Keep in a well-ventilated room. Do not transport with food and feedstuffs. T symbol R: 10-23/24/25 S: 1/2-45 UN Hazard Class: 3 UN Subsidiary Risks: 6.1 UN Packing Group: II SEE IMPORTANT INFORMATION ON BACK ICSC: 1465 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards n-BUTYRONITRILE ICSC: 1465 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS LIQUID , WITH CHARACTERISTIC ODOUR. PHYSICAL DANGERS: The vapour mixes well with air, explosive mixtures are formed easily. CHEMICAL DANGERS: The substance decomposes on burning, on contact with hot surfaces or flames or acids producing toxic and corrosive fumes including hydrogen cyanide and nitrogen oxides . Reacts violently with strong acids , strong bases , strong oxidants and strong reducing agents . OCCUPATIONAL EXPOSURE LIMITS: TLV not established. ROUTES OF EXPOSURE: The substance can be absorbed into the body by ingestion, by inhalation and through the skin. INHALATION RISK: A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster. EFFECTS OF SHORT-TERM EXPOSURE: The vapour is mildly irritating to the eyes , the skin and the respiratory tract . The substance may cause effects on the cellular respiration (inhibition) , resulting in convulsions , cardiac disorders and respiratory failure . Exposure at high levels may result in death. The effects may be delayed. Medical observation is indicated. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: PHYSICAL PROPERTIES Boiling point: 116-118°C Melting point: -112°C Relative density (water = 1): 0.8 Solubility in water, g/100 ml at 25°C: 3 Vapour pressure, kPa at 20°C: 2 Relative vapour density (air = 1): 2.4 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.02 Flash point: 17°C Auto-ignition temperature: 501°C Explosive limits, vol% in air: 1.6-? Octanol/water partition coefficient as log Pow: 0.5-0.6 ENVIRONMENTAL DATA This substance may be hazardous in the environment; special attention should be given to birds. N O T E S Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. Depending on the degree of exposure, periodic medical examination is suggested. Transport Emergency Card: TEC (R)-30GFT1-II NFPA Code: H3; F3; R; 0 ADDITIONAL INFORMATION ICSC: 1465 n-BUTYRONITRILE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.