International Chemical Safety Cards DISULFOTON ICSC: 1408 Dithiodemeton O,O-Diethyl S-(2-ethylmercaptoethyl) dithiophosphate O,O-Diethyl S-2-(ethylthio)ethyl phosphorodithioate C8H19O2PS3 Molecular mass: 274.41 ICSC #    1408 CAS #     298-04-4 RTECS # TD9275000 UN #        3018 EC #         015-060-00-3 October 16, 2001 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames. Powder, water spray, foam, carbon dioxide. EXPLOSION EXPOSURE STRICT HYGIENE! PREVENT GENERATION OF MISTS! IN ALL CASES CONSULT A DOCTOR!  •INHALATION Pupillary constriction, muscle cramp, excessive salivation. Sweating. Nausea. Laboured breathing. Dizziness. Convulsions. Unconsciousness. Ventilation, local exhaust, or breathing protection. Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.  •SKIN EASILY ABSORBED. (See Inhalation). Protective gloves. Protective clothing. Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.  •EYES Face shield or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Abdominal cramps. Diarrhoea. Vomiting. (Further see Inhalation). Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT let this chemical enter the environment. Personal protection: chemical protection suit including self-contained breathing apparatus. Provision to contain effluent from fire extinguishing. Separated from food and feedstuffs . Well closed. Do not transport with food and feedstuffs. Marine pollutant. T+ symbol N symbol R: 27/28-50/53 S: 1/2-28-36/37-45-60-61 UN Hazard Class: 6.1 UN Packing Group: I SEE IMPORTANT INFORMATION ON BACK ICSC: 1408 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards DISULFOTON ICSC: 1408 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: OILY COLOURLESS LIQUID , WITH CHARACTERISTIC ODOUR. PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on burning producing toxic fumes including phosphorous oxides and sulfur oxides . OCCUPATIONAL EXPOSURE LIMITS: TLV: (Inhalable fraction) 0.05 mg/m³ as TWA; (skin); A4 (not classifiable as a human carcinogen); BEI issued; (ACGIH 2004). MAK not established. ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. INHALATION RISK: Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying. EFFECTS OF SHORT-TERM EXPOSURE: The substance may cause effects on the nervous system , resulting in convulsions and respiratory failure . Exposure above the OEL may result in death. Cholinesterase inhibitor. The effects may be delayed. Medical observation is indicated. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: Cholinesterase inhibitor; cumulative effect is possible: see acute hazards/symptoms. PHYSICAL PROPERTIES Boiling point at 0.2kPa: 132-133°C Relative density (water = 1): 1.14 Solubility in water: none Vapour pressure, Pa at 20°C: 0.02 Octanol/water partition coefficient as log Pow: 4.02 ENVIRONMENTAL DATA The substance is very toxic to aquatic organisms. This substance may be hazardous in the environment; special attention should be given to birds and honey bees. This substance does enter the environment under normal use. Great care, however, should be given to avoid any additional release, e.g. through inappropriate disposal. N O T E S Depending on the degree of exposure, periodic medical examination is suggested. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. If the substance is formulated with solvent(s) also consult the card(s) (ICSC) of the solvent(s). Carrier solvents used in commercial formulations may change physical and toxicological properties. Do NOT take working clothes home. Card has been partly updated in April 2005. See section Occupational Exposure Limits. Transport Emergency Card: TEC (R)-61GT6-I ADDITIONAL INFORMATION ICSC: 1408 DISULFOTON (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.