International Chemical Safety Cards BUTYRIC ACID ICSC: 1334 n-Butanoic acid Ethylacetic acid 1-Propanecarboxylic acid Butanic acid C4H8O2 / CH3CH2CH2COOH Molecular mass: 88.1 ICSC #    1334 CAS #     107-92-6 RTECS # ES5425000 UN #        2820 EC #         607-135-00-X November 23, 1998 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames. Powder, alcohol-resistant foam, water spray, carbon dioxide. EXPLOSION Above 72°C explosive vapour/air mixtures may be formed. Above 72°C use a closed system, ventilation. In case of fire: keep drums, etc., cool by spraying with water. EXPOSURE AVOID ALL CONTACT! IN ALL CASES CONSULT A DOCTOR!  •INHALATION Sore throat. Cough. Burning sensation. Shortness of breath. Laboured breathing. Symptoms may be delayed (see Notes). Ventilation, local exhaust, or breathing protection. Fresh air, rest. Artificial respiration if indicated. Refer for medical attention.  •SKIN Pain. Redness. Blisters. Skin burns. Protective gloves. Protective clothing. Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention.  •EYES Pain. Redness. Severe deep burns. Loss of vision. Face shield, or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Burning sensation. Abdominal pain. Shock or collapse. Do not eat, drink, or smoke during work. Rinse mouth. Do NOT induce vomiting. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Collect leaking liquid in sealable containers. Cautiously neutralize remainder with soda lime. Then wash away with plenty of water. Do NOT let this chemical enter the environment. (Extra personal protection: complete protective clothing including self-contained breathing apparatus). Separated from strong oxidants, strong bases, food and feedstuffs. Do not transport with food and feedstuffs. C symbol R: 34 S: 1/2-26-36-45 UN Hazard Class: 8 UN Packing Group: III SEE IMPORTANT INFORMATION ON BACK ICSC: 1334 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards BUTYRIC ACID ICSC: 1334 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS OILY LIQUID , WITH CHARACTERISTIC ODOUR. PHYSICAL DANGERS: CHEMICAL DANGERS: The substance is a medium strong acid. Reacts with bases and strong oxidants. Attacks many metals. OCCUPATIONAL EXPOSURE LIMITS: TLV not established. MAK not established. ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its vapour. INHALATION RISK: No indication can be given about the rate in which a harmful concentration in the air is reached on evaporation of this substance at 20°C. EFFECTS OF SHORT-TERM EXPOSURE: The substance is corrosive to the eyes, the skin and the respiratory tract. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: PHYSICAL PROPERTIES Boiling point: 164°C Melting point: -7.9°C Relative density (water = 1): 0.96 Solubility in water: miscible Vapour pressure, Pa at 20°C: 57 Relative vapour density (air = 1): 3 Flash point: 72°C c.c. Auto-ignition temperature: 452°C Explosive limits, vol% in air: 2-10 Octanol/water partition coefficient as log Pow: 0.79 ENVIRONMENTAL DATA The substance is harmful to aquatic organisms. N O T E S Transport Emergency Card: TEC (R)-80G20C NFPA Code: H3; F2 R0; ADDITIONAL INFORMATION ICSC: 1334 BUTYRIC ACID (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.