International Chemical Safety Cards PICLORAM ICSC: 1246 4-Amino-3,5,6-trichloro-2-pyridinecarboxylic acid 4-Amino-3,5,6-trichloropicolinic acid C6H3Cl3N2O2 Molecular mass: 241.5 ICSC #    1246 CAS #     1918-02-1 RTECS # TJ7525000 March 15, 1995 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. Liquid formulations containing organic solvents may be flammable. NO open flames. Water spray, foam, powder. EXPLOSION EXPOSURE PREVENT DISPERSION OF DUST!  •INHALATION Burning sensation. Cough. Ventilation (not if powder). Avoid inhalation of fine dust and mist. Fresh air, rest.  •SKIN Redness. Protective gloves. Protective clothing. Remove contaminated clothes. Rinse and then wash skin with water and soap.  •EYES Redness. Pain. Safety goggles or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Burning sensation. Cough. Nausea. Do not eat, drink, or smoke during work. Wash hands before eating. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Do NOT wash away into sewer. Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. Personal protection: P2 filter respirator for harmful particles. Do NOT let this chemical enter the environment. Separated from food and feedstuffs . R: S: SEE IMPORTANT INFORMATION ON BACK ICSC: 1246 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards PICLORAM ICSC: 1246 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS CRYSTALS OR WHITE POWDER , WITH CHARACTERISTIC ODOUR. PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on heating producing nitrogen oxides (see ICSC 0067, ICSC 0930) and hydrogen chloride (see ICSC 0163). Reacts with strong bases . Attacks mild steel. OCCUPATIONAL EXPOSURE LIMITS: TLV: 10 mg/m³ as TWA; A4 (not classifiable as a human carcinogen); (ACGIH 2004). OSHA PEL: TWA 15 mg/m3 (total) TWA 5 mg/m3 (resp) NIOSH REL: See Appendix D NIOSH IDLH: No data ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation and by ingestion. INHALATION RISK: Evaporation at 20°C is negligible; a nuisance-causing concentration of airborne particles can, however, be reached quickly on spraying or when dispersed, especially if powdered. EFFECTS OF SHORT-TERM EXPOSURE: The substance is irritating to the eyes , the skin and the respiratory tract . EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: The substance may have effects on the liver. PHYSICAL PROPERTIES Decomposes below melting point at 218-219°C Solubility in water: poor Octanol/water partition coefficient as log Pow: 1.9 ENVIRONMENTAL DATA The substance is toxic to aquatic organisms. This substance may be hazardous to the environment; special attention should be given to soil organisms, aquatic organisms. This substance does enter the environment under normal use. Great care, however, should be given to avoid any additional release, e.g. through inappropriate disposal. N O T E S Insufficient data are available on the effect of this substance on human health, therefore utmost care must be taken. Carrier solvents used in commercial formulations may change physical and toxicological properties. Do NOT take working clothes home. Tordon, Amdon, ATCLP, Borolin, K-PIN, Chloramp, Grazon are trade names. Card has been partly updated in April 2005. See sections Occupational Exposure Limits, Physical properties. ADDITIONAL INFORMATION ICSC: 1246 PICLORAM (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.