International Chemical Safety Cards TETRAMETHYL SUCCINONITRILE ICSC: 1121 Tetramethylsuccinic acid dinitrile Tetramethylbutanedinitrile TMSN C8H12N2 / (CH3)2C(CN)C(CN)(CH3)2 Molecular mass: 136.2 ICSC #    1121 CAS #     3333-52-6 RTECS # WN4025000 UN #        2811 October 20, 1999 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames. NO contact with strong oxidants. Powder, water spray, foam, carbon dioxide. EXPLOSION EXPOSURE PREVENT DISPERSION OF DUST! STRICT HYGIENE!  •INHALATION Convulsions. Dizziness. Headache. Nausea. Unconsciousness. Vomiting. Ventilation (not if powder), local exhaust, or breathing protection. Fresh air, rest. Refer for medical attention.  •SKIN MAY BE ABSORBED! (See Inhalation). Protective gloves. Protective clothing. Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.  •EYES Safety goggles or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION (See Inhalation). Do not eat, drink, or smoke during work. Wash hands before eating. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. Personal protection: complete protective clothing including self-contained breathing apparatus. Separated from strong oxidants, food and feedstuffs . Cool. Dry. Keep in a well-ventilated room. Do not transport with food and feedstuffs. R: S: UN Hazard Class: 6.1 UN Packing Group: II SEE IMPORTANT INFORMATION ON BACK ICSC: 1121 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards TETRAMETHYL SUCCINONITRILE ICSC: 1121 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS ODOURLESS SOLID IN VARIOUS FORMS PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on heating producing toxic fumesincluding cyanidesandnitrogen oxides. Reacts with strong oxidants causing fire and explosion hazard. OCCUPATIONAL EXPOSURE LIMITS: TLV: 0.5 ppm as TWA; (skin); (ACGIH 2004). MAK: IIb (not established but data is available); skin absorption (H); (DFG 2004). OSHA PEL: TWA 3 mg/m3 (0.5 ppm) skin NIOSH REL: TWA 3 mg/m3 (0.5 ppm) skin NIOSH IDLH: 5 ppm ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. INHALATION RISK: No indication can be given about the rate in which a harmful concentration in the air is reached on evaporation of this substance at 20°C. EFFECTS OF SHORT-TERM EXPOSURE: The substance may cause effects on the central nervous system . Exposure at high concentration may result in death. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: PHYSICAL PROPERTIES Melting point: 170°C (sublimes) Density: 1.07 g/ml Solubility in water: none ENVIRONMENTAL DATA N O T E S The substance is combustible but no flash point is available in literature. Insufficient data are available on the effect of this substance on human health, therefore utmost care must be taken. Card has been partly updated in April 2005. See sections Occupational Exposure Limits, Emergency Response. Transport Emergency Card: TEC (R)-61GT2-II ADDITIONAL INFORMATION ICSC: 1121 TETRAMETHYL SUCCINONITRILE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.