International Chemical Safety Cards BENZOYL CHLORIDE ICSC: 1015 Benzenecarbonyl chloride Benzoic acid chloride alpha-Chlorobenzaldehyde C7H5ClO / C6H5COCl Molecular mass: 140.57 ICSC #    1015 CAS #     98-88-4 RTECS # DM6600000 UN #        1736 EC #         607-012-00-0 April 13, 2000 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. Many reactions may cause fire or explosion. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames. NO contact with incompatible substances (see Chemical Dangers). NO contact with hot surfaces. Alcohol-resistant foam, powder, carbon dioxide, NO water. EXPLOSION Above 72°C explosive vapour/air mixtures may be formed. Above 72°C use a closed system, ventilation, and explosion-proof electrical equipment. In case of fire: cool drums, etc., by spraying with water but avoid contact of the substance with water. EXPOSURE PREVENT GENERATION OF MISTS! STRICT HYGIENE! IN ALL CASES CONSULT A DOCTOR!  •INHALATION Burning sensation. Cough. Shortness of breath. Sore throat. Laboured breathing. Symptoms may be delayed (see Notes). Avoid inhalation of fine dust and mist. Closed system and ventilation. Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention. See Notes.  •SKIN Redness. Skin burns. Burning sensation. Pain. Blisters. Protective gloves. Protective clothing. Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention. Wear protective gloves when administering first aid.  •EYES Redness. Pain. Severe deep burns. Face shield or or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Burning sensation. Abdominal pain. Shock or collapse. (Further see Inhalation). Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Rest. Do NOT induce vomiting. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT wash away into sewer. Chemical protection suit including self-contained breathing apparatus. Separated from food and feedstuffs , incompatible materials (see Chemical Dangers). Dry. Well closed. Airtight. Do not transport with food and feedstuffs. C symbol R: 34 S: 1/2-26-45 UN Hazard Class: 8 UN Packing Group: II SEE IMPORTANT INFORMATION ON BACK ICSC: 1015 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards BENZOYL CHLORIDE ICSC: 1015 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: FUMING COLOURLESS LIQUID , WITH PUNGENT ODOUR. PHYSICAL DANGERS: The vapour is heavier than air. CHEMICAL DANGERS: On contact with hot surfaces or flames this substance decomposes forming highly toxic and corrosive gases ( phosgene and hydrogen chloride ). The substance decomposes rapidly on heating or on contact with alkalis, alcohols, amines and dimethyl sulphoxide - see ICSC 0459 , causing fire and explosion hazard. Reacts violently with strong oxidants. Reacts with water or steam producing heat, and corrosive fumes ( hydrogen chloride - see ICSC 0163) . Attacks many metals forming flammable hydrogen gas (see ICSC 0001), also on contact with metal salts. OCCUPATIONAL EXPOSURE LIMITS: TLV: 0.5 ppm (Ceiling value); (ACGIH 2004). MAK: Carcinogen category: 3B; (DFG 2004). ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation and by ingestion. INHALATION RISK: Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly. EFFECTS OF SHORT-TERM EXPOSURE: Tear drawing. The substance is corrosive to the eyes, the skin and the respiratory tract. Corrosive on ingestion. Inhalation of the vapour or aerosol may cause lung oedema (see Notes). EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: PHYSICAL PROPERTIES Boiling point: 197.2°C Melting point: -1°C Relative density (water = 1): 1.21 Solubility in water: reaction Vapour pressure, Pa at 20°C: 50 Relative vapour density (air = 1): 4.88 Flash point: 72°C c.c. Auto-ignition temperature: 197.2°C Explosive limits, vol% in air: 2.5-27 ENVIRONMENTAL DATA The substance is harmful to aquatic organisms. N O T E S Reacts violently with fire extinguishing agents such as water. The occupational exposure limit value should not be exceeded during any part of the working exposure. The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. Immediate administration of an appropriate inhalation therapy by a doctor or a person authorized by him/her, should be considered. Card has been partly updated in April 2005. See sections Occupational Exposure Limits, Emergency Response. Transport Emergency Card: TEC (R)-80GC3-II+III NFPA Code: H 3; F 2; R 1; W ADDITIONAL INFORMATION ICSC: 1015 BENZOYL CHLORIDE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.