International Chemical Safety Cards DL-METHIONINE ICSC: 0919 2-Amino-4-(methylthio)butyric acid C5H11NO2S / CH3S(CH2)2CH(NH2)COOH Molecular mass: 149.2 ICSC #    0919 CAS #     59-51-8 RTECS # PD0456000 April 10, 1997 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Gives off irritating or toxic fumes (or gases) in a fire. Powder, water spray, foam, carbon dioxide. EXPLOSION EXPOSURE  •INHALATION Local exhaust. Fresh air, rest.  •SKIN Rinse skin with plenty of water or shower.  •EYES Safety spectacles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Do not eat, drink, or smoke during work. Rinse mouth. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Sweep spilled substance into containers. Carefully collect remainder, then remove to safe place. Separated from strong oxidants. Well closed. R: S: SEE IMPORTANT INFORMATION ON BACK ICSC: 0919 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards DL-METHIONINE ICSC: 0919 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS CRYSTALS OR WHITE POWDER. PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on heating producing toxic fumes of sulfur oxides, nitrous oxides. OCCUPATIONAL EXPOSURE LIMITS: TLV not established. MAK not established. ROUTES OF EXPOSURE: The substance can be absorbed into the body by ingestion. INHALATION RISK: EFFECTS OF SHORT-TERM EXPOSURE: EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: PHYSICAL PROPERTIES Melting point (decomposes): 281°C Relative density (water = 1): 1.3 Solubility in water, g/100 ml at 20°C: 4.8 ENVIRONMENTAL DATA N O T E S Neston, Lobamine, Dyprin, Cynaron, Acymethin are trade names. ADDITIONAL INFORMATION ICSC: 0919 DL-METHIONINE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.