International Chemical Safety Cards DIOXATHION (ISOMER MIXTURE) ICSC: 0883 S,S'-(1,4-Dioxane-2,3-diyl) O,O,O',O'-tetraethyl-bis-(phosphorodithioate) C12H26O6P2S4 Molecular mass: 456.5 ICSC #    0883 CAS #     78-34-2 RTECS # TE3350000 UN #        3018 EC #         015-063-00-X March 23, 1998 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Not combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames. In case of fire in the surroundings: powder, water spray, foam, carbon dioxide . EXPLOSION Risk of fire and explosion if formulations contain flammable/explosive solvents. EXPOSURE PREVENT GENERATION OF MISTS! STRICT HYGIENE! AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN! IN ALL CASES CONSULT A DOCTOR!  •INHALATION Pupillary constriction, muscle cramp, excessive salivation. Sweating. Nausea. Dizziness. Laboured breathing. Convulsions. Unconsciousness. Ventilation, local exhaust, or breathing protection. Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.  •SKIN MAY BE ABSORBED! (See Inhalation). Protective gloves. Protective clothing. Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.  •EYES Blurred vision. Face shield, or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Abdominal cramps. Diarrhoea. Vomiting. (Further see Inhalation). Do not eat, drink, or smoke during work. Wash hands before eating. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT wash away into sewer. Do NOT let this chemical enter the environment. Personal protection: complete protective clothing including self-contained breathing apparatus. Separated from food and feedstuffs . Dry. Keep in a well-ventilated room. Do not transport with food and feedstuffs. Marine pollutant. T+ symbol N symbol R: 24-26/28-50/53 S: 1/2-28-36/37-45-60-61 UN Hazard Class: 6.1 UN Packing Group: II SEE IMPORTANT INFORMATION ON BACK ICSC: 0883 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards DIOXATHION (ISOMER MIXTURE) ICSC: 0883 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: VISCOUS BROWN LIQUID. PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on heating >135°C, producing toxic fumes including phosphorus oxides and sulfur oxides . Attacks iron and tin surfaces. Hydrolyzed by alkalies. OCCUPATIONAL EXPOSURE LIMITS: TLV: 0.1 mg/m³ as TWA; (skin); A4; (ACGIH 2004). MAK not established. OSHA PEL: none NIOSH REL: TWA 0.2 mg/m3 skin NIOSH IDLH: No data ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. INHALATION RISK: Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying. EFFECTS OF SHORT-TERM EXPOSURE: The substance may cause effects on the nervous system , resulting in convulsions , respiratory failure . Cholinesterase inhibitor. Exposure at high level may result in death. Medical observation is indicated. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: Cholinesterase inhibitor; cumulative effect is possible: see acute hazards/symptoms. PHYSICAL PROPERTIES Melting point: -20°C Relative density (water = 1): 1.26 at 26°C Solubility in water: none Octanol/water partition coefficient as log Pow: 3.0 ENVIRONMENTAL DATA The substance is very toxic to aquatic organisms. Avoid release to the environment in circumstances different to normal use. N O T E S Depending on the degree of exposure, periodic medical examination is suggested. The symptoms of acute intoxication do not become manifest until 30 minutes to 2 hours. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. If the substance is formulated with solvent(s) also consult the card(s) (ICSC) of the solvent(s). Carrier solvents used in commercial formulations may change physical and toxicological properties. Do NOT take working clothes home. Delnav (Hercules AC258), Deltic and Navadel are trade names. Card has been partly updated in October 2004. See sections Occupational Exposure Limits, EU classification, Emergency Response. Transport Emergency Card: TEC (R)-61GT6-II ADDITIONAL INFORMATION ICSC: 0883 DIOXATHION (ISOMER MIXTURE) (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.