International Chemical Safety Cards AZINPHOS-METHYL ICSC: 0826 Phosphorodithioic acid 0,0-dimethyl S-((4-oxo-11,2,3-benzotriazin-3-(4H)-yl)methyl) ester S-3,4-Dihydro-4-oxo-1,2,3-benzotriazin-3-ylmethyl) O,O-dimethyl phosphorodithioate C10H12N3O3PS2 Molecular mass: 317.3 ICSC #    0826 CAS #     86-50-0 RTECS # TE1925000 UN #        2783 EC #         015-039-00-9 March 26, 1998 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames. Powder, water spray, foam, carbon dioxide. EXPLOSION EXPOSURE PREVENT DISPERSION OF DUST! STRICT HYGIENE! AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN! IN ALL CASES CONSULT A DOCTOR!  •INHALATION Headache. Pupillary constriction, muscle cramp, excessive salivation. Sweating. Nausea. Dizziness. Wheezing. Laboured breathing. Convulsions. Unconsciousness. Ventilation (not if powder), local exhaust, or breathing protection. Fresh air, rest. Artificial respiration if indicated. Refer for medical attention.  •SKIN MAY BE ABSORBED! (See Inhalation). Protective gloves. Protective clothing. Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.  •EYES Blurred vision. Face shield, or eye protection in combination with breathing protection if powder. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Abdominal cramps. Vomiting. Diarrhoea. Blurred vision. (Further see Inhalation). Do not eat, drink, or smoke during work. Wash hands before eating. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Do NOT wash away into sewer. Sweep spilled substance into sealable containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. (Extra personal protection: complete protective clothing including self-contained breathing apparatus). Separated from food and feedstuffs. Well closed. Do not transport with food and feedstuffs. Severe marine pollutant. T+ symbol R: 24-28 S: 1/2-28-36/37-45 UN Hazard Class: 6.1 UN Packing Group: II SEE IMPORTANT INFORMATION ON BACK ICSC: 0826 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards AZINPHOS-METHYL ICSC: 0826 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS CRYSTALS. PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on heating above 200°C and on burning producing toxic and corrosive fumes including nitrogen oxides, phosphorous oxides, sulfur oxides. OCCUPATIONAL EXPOSURE LIMITS: TLV: 0.2 mg/m3 (skin) (ACGIH 1997). MAK: 0.2 mg/m3; III, H (1996). OSHA PEL: TWA 0.2 mg/m3 skin NIOSH REL: TWA 0.2 mg/m3 skin NIOSH IDLH: 10 mg/m3 ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. INHALATION RISK: Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying or when dispersed, especially if powdered. EFFECTS OF SHORT-TERM EXPOSURE: The substance may cause effects on the nervous system , resulting in convulsions, respiratory failure. Cholinesterase inhibitor. Exposure may result in unconsciousness or death. The effects may be delayed. Medical observation is indicated. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: Cholinesterase inhibitor; cumulative effect is possible: see acute hazards/symptoms. PHYSICAL PROPERTIES Melting point: 73-74°C Density: 1.4 g/cm3 Solubility in water: none Vapour pressure, Pa at 20°C: < 0.001 Octanol/water partition coefficient as log Pow: 2.75 ENVIRONMENTAL DATA The substance is very toxic to aquatic organisms. This substance may be hazardous to the environment; special attention should be given to honey bees. Avoid release to the environment in circumstances different to normal use. N O T E S The technical material is a brown waxy solid. Depending on the degree of exposure, periodic medical examination is indicated. The symptoms of acute intoxication do not become manifest until 30 minutes to 1-2 hours. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. If the substance is formulated with solvent(s) also consult the card(s) (ICSC) of the solvent(s). Carrier solvents used in commercial formulations may change physical and toxicological properties. Do NOT take working clothes home. Guthion and Gusathion M are trade names. Transport Emergency Card: TEC (R)-61G41b ADDITIONAL INFORMATION ICSC: 0826 AZINPHOS-METHYL (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.