International Chemical Safety Cards KETENE ICSC: 0812 Carbomethene Ethenone Ketoethylene C2H2O / CH2=C=O Molecular mass: 42.0 ICSC #    0812 CAS #     463-51-4 RTECS # OA7700000 October 10, 1997 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Extremely flammable. NO open flames, NO sparks, and NO smoking. Powder, carbon dioxide, NO water. EXPLOSION Gas/air mixtures are explosive. Closed system, ventilation, explosion-proof electrical equipment and lighting. In case of fire: cool cylinder by spraying with water but avoid contact of the substance with water. EXPOSURE STRICT HYGIENE!  •INHALATION Cough. Shortness of breath. Symptoms may be delayed (see Notes). Ventilation, local exhaust, or breathing protection. Fresh air, rest. Half-upright position. Artificial respiration if indicated. Refer for medical attention.  •SKIN Redness. Protective gloves. Remove contaminated clothes. Rinse skin with plenty of water or shower.  •EYES Redness. Pain. Safety goggles, or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Evacuate danger area! Consult an expert! Ventilation. (Extra personal protection: gas-tight chemical protection suit including self-contained breathing apparatus). The substance cannot be stored or shipped. R: S: SEE IMPORTANT INFORMATION ON BACK ICSC: 0812 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards KETENE ICSC: 0812 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS GAS , WITH CHARACTERISTIC ODOUR. PHYSICAL DANGERS: The gas is heavier than air and may travel along the ground; distant ignition possible. CHEMICAL DANGERS: The substance may readily polymerize. Reacts violently with many organic compounds. Reacts with water to form acetic acid. Decomposes in alcohol and ammonia. OCCUPATIONAL EXPOSURE LIMITS: TLV: 0.5 ppm; 0.86 mg/m3 (as TWA); 1.5 ppm; 2.6 mg/m3 (as STEL) (ACGIH 1997). OSHA PEL: TWA 0.5 ppm (0.9 mg/m3) NIOSH REL: TWA 0.5 ppm (0.9 mg/m3) ST 1.5 ppm (3 mg/m3) NIOSH IDLH: 5 ppm ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation. INHALATION RISK: A harmful concentration of this gas in the air will be reached very quickly on loss of containment. EFFECTS OF SHORT-TERM EXPOSURE: The substance irritates the eyes, the skin, and the respiratory tract. Inhalation of the gas may cause lung oedema (see Notes). The effects may be delayed. Medical observation is indicated. See Notes. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: Lungs may be affected by repeated or prolonged exposure , resulting in emphesema and fibrosis. PHYSICAL PROPERTIES Boiling point: -56°C Melting point: -150°C Solubility in water: reaction Relative vapour density (air = 1): 1.4 Flash point: Flammable Gas ENVIRONMENTAL DATA N O T E S Reacts violently with fire extinguishing agents such as water. The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation is therefore essential. Immediate administration of an appropriate spray, by a doctor or a person authorized by him/her, should be considered. ADDITIONAL INFORMATION ICSC: 0812 KETENE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.