International Chemical Safety Cards MALEIC ANHYDRIDE ICSC: 0799 2,5-Furandione Dihydro-2,5-dioxofuran Maleic acid anhydride cis-Butanedioic anhydride C4H2O3 Molecular mass: 98.1 ICSC #    0799 CAS #     108-31-6 RTECS # ON3675000 UN #        2215 EC #         607-096-00-9 October 09, 1997 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. NO open flames. Water spray, alcohol-resistant foam, carbon dioxide, NO powder. EXPLOSION EXPOSURE STRICT HYGIENE!  •INHALATION Burning sensation. Cough. Headache. Laboured breathing. Nausea. Shortness of breath. Sore throat. Local exhaust or breathing protection. Fresh air, rest. Half-upright position. Refer for medical attention.  •SKIN Dry skin. Redness. Skin burns. Pain. (see Notes). Protective gloves. Protective clothing. First rinse with plenty of water, then remove contaminated clothes and rinse again.  •EYES Redness. Pain. Lacrymation. Severe deep burns. Safety goggles, or eye protection in combination with breathing protection if powder. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Abdominal pain. Burning sensation. Do not eat, drink, or smoke during work. Rinse mouth. Do NOT induce vomiting. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. Wash away remainder with plenty of water. (Extra personal protection: P2 filter respirator for harmful particles). Separated from strong oxidants, strong bases, food and feedstuffs. Dry. Airtight. Do not transport with food and feedstuffs. Xn symbol R: 22-36/37/38-42 S: 2-22-28-39 UN Hazard Class: 8 UN Packing Group: III SEE IMPORTANT INFORMATION ON BACK ICSC: 0799 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards MALEIC ANHYDRIDE ICSC: 0799 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS OR WHITE CRYSTALS , WITH PUNGENT ODOUR. PHYSICAL DANGERS: CHEMICAL DANGERS: The solution in water is a medium strong acid. Reacts with strong oxidants. OCCUPATIONAL EXPOSURE LIMITS: TLV: 0.25 ppm; 1.0 mg/m3 (as TWA) (ACGIH 1997). MAK: 0.1 ppm; 0.4 mg/m3; (1996) OSHA PEL: TWA 1 mg/m3 (0.25 ppm) NIOSH REL: TWA 1 mg/m3 (0.25 ppm) NIOSH IDLH: 10 mg/m3 ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. INHALATION RISK: A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C. EFFECTS OF SHORT-TERM EXPOSURE: The substance irritates severely the eyes, the skin and the respiratory tract. Inhalation of the substance may cause asthmatic reactions (see Notes). EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: Repeated or prolonged contact with skin may cause dermatitis. Repeated or prolonged inhalation exposure may cause asthma. PHYSICAL PROPERTIES Boiling point: 202°C Melting point: 53°C Relative density (water = 1): 1.5 Solubility in water, g/100 ml: 40 Vapour pressure, Pa at 25°C: 25 Relative vapour density (air = 1): 3.4 Flash point: 102°C c.c. Auto-ignition temperature: 477°C Explosive limits, vol% in air: 1.4-7.1 ENVIRONMENTAL DATA N O T E S Reacts violently with fire extinguishing agents such as powder. Depending on the degree of exposure, periodic medical examination is indicated. The symptoms of asthma often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. Anyone who has shown symptoms of asthma due to this substance should avoid all further contact with this substance. Maleic anhydride is transported also as hot liquid (70°C); contact of the skin should be avoided. The odour warning when the exposure limit value is exceeded is insufficient. Transport Emergency Card: TEC (R)-824 NFPA Code: H3; F1; R1; ADDITIONAL INFORMATION ICSC: 0799 MALEIC ANHYDRIDE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.