International Chemical Safety Cards CHLOROACETONE ICSC: 0760 1-Chloro-2-propanone Acetonyl chloride Monochloroacetone C3H5ClO / ClCH2COCH3 Molecular mass: 92.5 ICSC #    0760 CAS #     78-95-5 RTECS # UC0700000 UN #        1695 (stabilized) March 28, 1996 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Flammable. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames, NO sparks, and NO smoking. Powder, water spray, foam, carbon dioxide. EXPLOSION Above 28°C explosive vapour/air mixtures may be formed. Above 28°C use a closed system, ventilation, and explosion-proof electrical equipment. In case of fire: keep drums, etc., cool by spraying with water. EXPOSURE AVOID ALL CONTACT!  •INHALATION Sore throat. Cough. Burning sensation. Shortness of breath. Symptoms may be delayed (see Notes). Ventilation, local exhaust, or breathing protection. Fresh air, rest. Half-upright position. Artificial respiration if indicated. Refer for medical attention.  •SKIN MAY BE ABSORBED! Pain. Blisters. Delayed effects. Protective gloves. Protective clothing. Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention.  •EYES Redness. Pain. Severe deep burns. Face shield, or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Burning sensation. Abdominal cramps. Shock or collapse. Rinse mouth. Do NOT induce vomiting. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Evacuate danger area! Consult an expert! Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT wash away into sewer. (Extra personal protection: complete protective clothing including self-contained breathing apparatus). Fireproof. Separated from strong oxidants, food and feedstuffs . Keep in the dark. Store only if stabilized. Unbreakable packaging; put breakable packaging into closed unbreakable container. Do not transport with food and feedstuffs. R: S: UN Hazard Class: 6.1 UN Subsidiary Risks: 3 and 8 UN Packing Group: I SEE IMPORTANT INFORMATION ON BACK ICSC: 0760 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards CHLOROACETONE ICSC: 0760 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS LIQUID , WITH PUNGENT ODOUR. TURNS DARK AND RESINIFIES ON PROLONGED EXPOSURE TO LIGHT. PHYSICAL DANGERS: CHEMICAL DANGERS: The substance polymerizes slowly under the influence of light. The substance decomposes on heating or on burning producing toxic and corrosive fumes including hydrogen chloride phosgene . Reacts with strong oxidants. OCCUPATIONAL EXPOSURE LIMITS: TLV: 1 ppm; 3.8 mg/m3 C (skin) (ACGIH 1995-1996). ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation, through the skin, by ingestion , also as a vapour! INHALATION RISK: A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C. EFFECTS OF SHORT-TERM EXPOSURE: Corrosive. Tear drawing. The substance is corrosive to the eyes, the skin and the respiratory tract. Inhalation of the vapour of this substance may cause lung oedema (see Notes). The effects may be delayed. Medical observation is indicated. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: PHYSICAL PROPERTIES Boiling point: 120°C Melting point: -45°C Relative density (water = 1): 1.1 Solubility in water, g/100 ml at 20°C: 10 Vapour pressure, kPa at 25°C: 1.5 Relative vapour density (air = 1): 3.7 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.03 Flash point: 28°C c.c. Octanol/water partition coefficient as log Pow: 0.28 ENVIRONMENTAL DATA N O T E S Explosive limits are unknown in literature, although the substance is combustible and has a flash point < 55°C. The occupational exposure limit value should not be exceeded during any part of the working exposure. The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. Immediate administration of an appropriate inhalation therapy by a doctor or a person authorized by him/her, should be considered. An added stabilizer or inhibitor can influence the toxicological properties of this substance, consult an expert. The odour warning when the exposure limit value is exceeded is insufficient. Transport Emergency Card: TEC (R)-61G61b ADDITIONAL INFORMATION ICSC: 0760 CHLOROACETONE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.