International Chemical Safety Cards COPPER 8-QUINOLATE ICSC: 0756 Copper-8-hydroxyquinoline Oxine-copper 8-Quinolinol, copper(II) chelate Bis(8-oxyquinoline) copper C18H12CuN2O2 Molecular mass: 351.9 ICSC #    0756 CAS #     10380-28-6 RTECS # VC5250000 March 15, 1995 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire. Powder, water spray, foam, carbon dioxide. In case of fire in the surroundings: all extinguishing agents allowed. EXPLOSION EXPOSURE PREVENT DISPERSION OF DUST!  •INHALATION (see Ingestion). Local exhaust or breathing protection. Fresh air, rest. Artificial respiration if indicated. Refer for medical attention.  •SKIN Protective gloves. Remove contaminated clothes. Rinse skin with plenty of water or shower.  •EYES Safety goggles. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Abdominal pain. Diarrhoea. Laboured breathing. Vomiting. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Rest. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Do NOT wash away into sewer. Sweep spilled substance into sealable containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. R: S: SEE IMPORTANT INFORMATION ON BACK ICSC: 0756 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards COPPER 8-QUINOLATE ICSC: 0756 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: GREEN TO YELLOW CRYSTALLINE POWDER. PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on burning producing toxic and corrosive fumes including copper and nitrogen oxides. OCCUPATIONAL EXPOSURE LIMITS: TLV not established. ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its aerosol and by ingestion. INHALATION RISK: Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly. EFFECTS OF SHORT-TERM EXPOSURE: Inhalation of its aerosol may cause asthmatic reactions (see Notes). EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: Repeated or prolonged inhalation exposure may cause asthma. PHYSICAL PROPERTIES Decomposes below melting point at 270°C Relative density (water = 1): 1.63 Solubility in water: none Octanol/water partition coefficient as log Pow: 2.46 ENVIRONMENTAL DATA The substance is very toxic to aquatic organisms. Avoid release to the environment in circumstances different to normal use. N O T E S The symptoms of asthma often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. Anyone who has shown symptoms of asthma due to this substance should avoid all further contact with this substance. Carrier solvents used in commercial formulations may change physical and toxicological properties. Bioquin, Cunilate, Dokirin, Fruitdo and Quinondo are trade names. ADDITIONAL INFORMATION ICSC: 0756 COPPER 8-QUINOLATE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.