International Chemical Safety Cards HEXAMETHYLENEDIAMINE ICSC: 0659 1,6-Diaminohexane 1,6-Hexanediamine HMD(A) C6H16N2 Molecular mass: 116.24 ICSC #    0659 CAS #     124-09-4 RTECS # MO1180000 UN #        2280 November 26, 1998 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. NO open flames. NO contact with hot surfaces. Powder, alcohol-resistant foam, water in large amounts, carbon dioxide. EXPLOSION In case of fire: keep drums, etc., cool by spraying with water. EXPOSURE STRICT HYGIENE!  •INHALATION Burning sensation. Cough. Laboured breathing. Shortness of breath. Sore throat. Symptoms may be delayed (see Notes). Ventilation (not if powder), local exhaust, or breathing protection. Fresh air, rest. Half-upright position. Artificial respiration if indicated. Refer for medical attention.  •SKIN MAY BE ABSORBED! Redness. Skin burns. Pain. Blisters. Protective gloves. Protective clothing. Rinse skin with plenty of water or shower. Refer for medical attention.  •EYES Redness. Pain. Severe deep burns. Safety spectacles, face shield, or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Abdominal cramps. Abdominal pain. Burning sensation. Shock or collapse. Do not eat, drink, or smoke during work. Rest. Refer for medical attention. See Notes. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Collect leaking liquid in sealable containers or sweep spilled substance into containers. Carefully collect remainder, then remove to safe place. Do NOT let this chemical enter the environment. (Extra personal protection: complete protective clothing including self-contained breathing apparatus). Separated from strong oxidants, strong acids. Well closed. Unbreakable packaging; put breakable packaging into closed unbreakable container. R: S: UN Hazard Class: 8 UN Packing Group: III SEE IMPORTANT INFORMATION ON BACK ICSC: 0659 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards HEXAMETHYLENEDIAMINE ICSC: 0659 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: HYGROSCOPIC PELLETS OR FLAKES , WITH CHARACTERISTIC ODOUR. PHYSICAL DANGERS: CHEMICAL DANGERS: On combustion, forms toxic and corrosive gases. Upon heating, toxic fumes are formed. The solution in water is a strong base, it reacts violently with acid and is corrosive. Reacts with oxidants. Attacks many metals in presence of water. OCCUPATIONAL EXPOSURE LIMITS: TLV: 0.5 ppm; 2.3 mg/m3 (as TWA) (ACGIH 1998). ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. INHALATION RISK: A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C. EFFECTS OF SHORT-TERM EXPOSURE: The substance is corrosive to the eyes, the skin and the respiratory tract. Corrosive on ingestion. Inhalation of the substance may cause lung oedema (see Notes). The effects may be delayed. Medical observation is indicated. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: Repeated or prolonged contact with skin may cause dermatitis. PHYSICAL PROPERTIES Boiling point: 199-205°C Melting point: 23-41°C Relative density (water = 1): 0.93 Solubility in water: soluble Vapour pressure, Pa at 50°C: 200 Relative vapour density (air = 1): 3.8 Flash point: 85°C c.c. Auto-ignition temperature: 305°C Explosive limits, vol% in air: 0.9-7.6 ENVIRONMENTAL DATA The substance is toxic to aquatic organisms. N O T E S The substance may exist as solid or liquid depending on ambient temperature. The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation is therefore essential. Immediate administration of an appropriate spray, by a doctor or a person authorized by him/her, should be considered. The recommendations on this Card also apply to hexamethylenediamine solution, 70-80 %, UN No. 1783. Transport Emergency Card: TEC (R)-80G16 NFPA Code: H2; F1; R1; ADDITIONAL INFORMATION ICSC: 0659 HEXAMETHYLENEDIAMINE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.