International Chemical Safety Cards 2-CHLOROACETAMIDE ICSC: 0640 alpha-Chloroacetamide C2H4ClNO / ClCH2CONH2 Molecular mass: 93.5 ICSC #    0640 CAS #     79-07-2 RTECS # AB5075000 UN #        2811 September 23, 1993 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Not combustible. Gives off irritating or toxic fumes (or gases) in a fire. In case of fire in the surroundings: all extinguishing agents allowed. EXPLOSION Solutions may explode during drying or concentration operations. EXPOSURE PREVENT DISPERSION OF DUST! AVOID ALL CONTACT! IN ALL CASES CONSULT A DOCTOR!  •INHALATION Burning sensation. Cough. Sore throat. Avoid inhalation of fine dust and mist. Local exhaust or breathing protection. Fresh air, rest. Refer for medical attention.  •SKIN Redness. Pain. Protective gloves. Protective clothing. Remove contaminated clothes. Rinse and then wash skin with water and soap.  •EYES Redness. Pain. Safety spectacles, face shield, or eye protection in combination with breathing protection if powder. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Sore throat. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Sweep spilled substance into sealable containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. (Extra personal protection: P3 filter respirator for toxic particles). Separated from strong oxidants, strong bases, strong acids, food and feedstuffs . Keep in a well-ventilated room. Do not transport with food and feedstuffs. R: S: UN Hazard Class: 6.1 SEE IMPORTANT INFORMATION ON BACK ICSC: 0640 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards 2-CHLOROACETAMIDE ICSC: 0640 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS TO YELLOW CRYSTALS , WITH CHARACTERISTIC ODOUR. PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on heating producing toxic fumes including nitrogen oxides and chlorine . Reacts with strong oxidants strong reducing agents strong acids and strong bases . OCCUPATIONAL EXPOSURE LIMITS: TLV not established. PDK not established. ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. INHALATION RISK: No indication can be given about the rate in which a harmful concentration in the air is reached on evaporation of this substance at 20°C. EFFECTS OF SHORT-TERM EXPOSURE: The substance is irritating to the eyes , the skin and the respiratory tract . The substance may cause effects on the heart, liver , spleen . EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: Repeated or prolonged contact may cause skin sensitization. PHYSICAL PROPERTIES Boiling point (decomposes): 225°C Melting point: 120°C Solubility in water, g/100 ml at 20°C: 98 Vapour pressure, kPa at 20°C: 0.007 Relative vapour density (air = 1): 3.2 ENVIRONMENTAL DATA N O T E S Transport Emergency Card: TEC (R)-61G11b ADDITIONAL INFORMATION ICSC: 0640 2-CHLOROACETAMIDE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.