International Chemical Safety Cards SALICYLIC ACID ICSC: 0563 2-Hydroxybenzoic acid o-Hydroxybenzoic acid C7H6O3 / HOC6H4COOH Molecular mass: 138.1 ICSC #    0563 CAS #     69-72-7 RTECS # VO0525000 April 11, 1997 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. NO open flames. Carbon dioxide, water spray, powder. EXPLOSION Finely dispersed particles form explosive mixtures in air. Prevent deposition of dust; closed system, dust explosion-proof electrical equipment and lighting. In case of fire: keep drums, etc., cool by spraying with water. EXPOSURE PREVENT DISPERSION OF DUST!  •INHALATION Cough. Sore throat (see Ingestion). Local exhaust or breathing protection. Fresh air, rest. Refer for medical attention.  •SKIN Redness. Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.  •EYES Redness. Pain. Safety goggles, or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Nausea. Vomiting. Ear ringing. Do not eat, drink, or smoke during work. Rinse mouth. Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting (extra personal protection: P2 filter respirator for harmful particles). Separated from strong oxidants. R: S: SEE IMPORTANT INFORMATION ON BACK ICSC: 0563 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards SALICYLIC ACID ICSC: 0563 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS CRYSTALLINE POWDER OR NEEDLE-SHAPED CRYSTALS. PHYSICAL DANGERS: Dust explosion possible if in powder or granular form, mixed with air. CHEMICAL DANGERS: The solution in water is a weak acid. Reacts with strong oxidants. OCCUPATIONAL EXPOSURE LIMITS: TLV not established. ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation and by ingestion. INHALATION RISK: Evaporation at 20°C is negligible; a nuisance-causing concentration of airborne particles can, however, be reached quickly by dispersing powder. EFFECTS OF SHORT-TERM EXPOSURE: The substance irritates the eyes, the skin and the respiratory tract. The substance may cause effects on the central nervous system and the acid-base balance in the body , resulting in delirium and tremors. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: Repeated or prolonged contact with skin may cause dermatitis. PHYSICAL PROPERTIES Sublimation point: 76°C Melting point: 159°C Relative density (water = 1): 1.4 Solubility in water, g/100 ml at 20°C: 0.2 Vapour pressure, Pa at 130°C: 114 Relative vapour density (air = 1): 4.8 Flash point: 157°C Auto-ignition temperature: 540°C Octanol/water partition coefficient as log Pow: 2.2 ENVIRONMENTAL DATA N O T E S Volatility becomes noticeable above 50-60°C. Anyone who has shown aspirin sensitization should never come in contact with this substance. NFPA Code: H0; F1; R0; ADDITIONAL INFORMATION ICSC: 0563 SALICYLIC ACID (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.