International Chemical Safety Cards n-BUTYLAMINE ICSC: 0374 1-Aminobutane 1-Butanamine Monobutylamine C4H11N / CH3(CH2)3NH2 Molecular mass: 73.1 ICSC #    0374 CAS #     109-73-9 RTECS # EO2975000 UN #        1125 EC #         612-005-00-0 October 07, 1997 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Highly flammable. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames, NO sparks, and NO smoking. Powder, alcohol-resistant foam, water in large amounts, carbon dioxide. EXPLOSION Vapour/air mixtures are explosive. Closed system, ventilation, explosion-proof electrical equipment and lighting. In case of fire: keep drums, etc., cool by spraying with water. EXPOSURE AVOID ALL CONTACT! IN ALL CASES CONSULT A DOCTOR!  •INHALATION Sore throat. Cough. Burning sensation. Headache. Flushing of the face. Vomiting. Dizziness. Shortness of breath. Laboured breathing. Symptoms may be delayed (see Notes). Ventilation, local exhaust, or breathing protection. Fresh air, rest. Half-upright position. Artificial respiration if indicated. Refer for medical attention.  •SKIN MAY BE ABSORBED! Pain. Redness. Blisters. Skin burns. Protective gloves. Protective clothing. Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention.  •EYES Pain. Redness. Severe deep burns. Loss of vision. Face shield, or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Burning sensation. Abdominal pain. Diarrhoea. Nausea. Vomiting. Shock or collapse. Do not eat, drink, or smoke during work. Rinse mouth. Do NOT induce vomiting. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Evacuate danger area! Consult an expert! Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT let this chemical enter the environment. (Extra personal protection: chemical protection suit including self-contained breathing apparatus). Fireproof. Separated from food and feedstuffs. See Chemical Dangers. Unbreakable packaging; put breakable packaging into closed unbreakable container. Do not transport with food and feedstuffs. F symbol C symbol R: 11-20/21/22-35 S: 1/2-3-16-26-29-36/37/39-45 UN Hazard Class: 3 UN Subsidiary Risks: 8 UN Packing Group: II SEE IMPORTANT INFORMATION ON BACK ICSC: 0374 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards n-BUTYLAMINE ICSC: 0374 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS LIQUID , WITH CHARACTERISTIC ODOUR. TURNS TO YELLOW ON STANDING. PHYSICAL DANGERS: The vapour is heavier than air and may travel along the ground; distant ignition possible. CHEMICAL DANGERS: The substance decomposes on heating or on burning producing toxic fumes including nitrogen oxides. The substance is a weak base. Reacts with strong oxidants and acids causing fire and explosion hazard. Attacks some metals in presence of water. OCCUPATIONAL EXPOSURE LIMITS: TLV: 5 ppm; 15 mg/m3 (ceiling values) (skin) (ACGIH 1997). OSHA PEL: C 5 ppm (15 mg/m3) skin NIOSH REL: C 5 ppm (15 mg/m3) skin NIOSH IDLH: 300 ppm ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its vapour, through the skin and by ingestion. INHALATION RISK: A harmful contamination of the air can be reached very quickly on evaporation of this substance at 20°C. EFFECTS OF SHORT-TERM EXPOSURE: The substance and the vapour is corrosive to the eyes, the skin and the respiratory tracts. Inhalation of the vapour may cause lung oedema (see Notes). The effects may be delayed. Medical observation is indicated. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: Repeated or prolonged contact with skin may cause dermatitis. PHYSICAL PROPERTIES Boiling point: 78°C Melting point: -50°C Relative density (water = 1): 0.74 Solubility in water: miscible Vapour pressure, kPa at 20°C: 10.9 Relative vapour density (air = 1): 2.5 Flash point: -12°C c.c. Auto-ignition temperature: 312°C Explosive limits, vol% in air: 1.7-9.8 Octanol/water partition coefficient as log Pow: 0.86 ENVIRONMENTAL DATA The substance is harmful to aquatic organisms. N O T E S The occupational exposure limit value should not be exceeded during any part of the working exposure. The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation is therefore essential. Immediate administration of an appropriate spray, by a doctor or a person authorized by him/her, should be considered. Transport Emergency Card: TEC (R)-655 NFPA Code: H3; F3; R0; ADDITIONAL INFORMATION ICSC: 0374 n-BUTYLAMINE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.