International Chemical Safety Cards ISOPROPYL CHLOROFORMATE ICSC: 0287 Isopropyl chlorocarbonate Chloroformic acid, isopropyl ester Carbonochloridic acid 1-methylethyl ester Isopropyl chloromethanate C4H7ClO2 / (CH3)2CHOCOCl Molecular mass: 122.6 ICSC #    0287 CAS #     108-23-6 RTECS # LQ6475000 UN #        2407 May 05, 2003 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Highly flammable. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames, NO sparks, and NO smoking. Carbon dioxide, dry powder, alcohol-resistant foam, dry sand. EXPLOSION Vapour/air mixtures are explosive. Closed system, ventilation, explosion-proof electrical equipment and lighting. Do NOT use compressed air for filling, discharging, or handling. In case of fire: cool drums, etc., by spraying with water but avoid contact of the substance with water. EXPOSURE STRICT HYGIENE! IN ALL CASES CONSULT A DOCTOR!  •INHALATION Burning sensation. Cough. Laboured breathing. Shortness of breath. Sore throat. Symptoms may be delayed (see Notes). Ventilation, local exhaust, or breathing protection. Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.  •SKIN Redness. Skin burns. Pain. Blisters. Protective gloves. Protective clothing. Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention.  •EYES Causes watering of the eyes. Redness. Pain. Severe deep burns. Safety goggles and face shield or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Abdominal pain. Burning sensation. Shock or collapse. Do not eat, drink, or smoke during work. Rinse mouth. Do NOT induce vomiting. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Ventilation. Remove all ignition sources. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT wash away into sewer. (Extra personal protection: chemical protection suit including self-contained breathing apparatus.) Fireproof. Separated from strong oxidants, food and feedstuffs . Dry. Well closed. Do not transport with food and feedstuffs. R: S: UN Hazard Class: 6.1 UN Subsidiary Risks: 3 and 8 UN Packing Group: I SEE IMPORTANT INFORMATION ON BACK ICSC: 0287 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards ISOPROPYL CHLOROFORMATE ICSC: 0287 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS LIQUID , WITH PUNGENT ODOUR. PHYSICAL DANGERS: The vapour is heavier than air and may travel along the ground; distant ignition possible. CHEMICAL DANGERS: The substance decomposes on heating producing toxic and corrosive fumes including hydrogen chloride and phosgene . Reacts violently with strong oxidants. Reacts with water to produce alcohol and hydrogen chloride (see ICSC 0163) . OCCUPATIONAL EXPOSURE LIMITS: TLV not established. ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its vapour and by ingestion. INHALATION RISK: No indication can be given about the rate in which a harmful concentration in the air is reached on evaporation of this substance at 20°C. EFFECTS OF SHORT-TERM EXPOSURE: Causes watering of the eyes. The substance is corrosive to the eyes, the skin and the respiratory tract. Corrosive on ingestion. Inhalation of vapour may cause lung oedema (see Notes). The effects may be delayed. Medical observation is indicated. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: PHYSICAL PROPERTIES Boiling point: 104.6°C Relative density (water = 1): 1.08 Solubility in water: slow reaction Vapour pressure, kPa at 20°C: 3 Relative vapour density (air = 1): 4.2 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.1 Flash point: 20°C c.c. Auto-ignition temperature: >500°C Explosive limits, vol% in air: 4-15 ENVIRONMENTAL DATA N O T E S Health effects of exposure to the substance have not been investigated adequately. The symptoms of lung oedema often do not become manifest until a few hours have passed and they are aggravated by physical effort. Rest and medical observation are therefore essential. Immediate administration of an appropriate inhalation therapy by a doctor or a person authorized by him/her, should be considered. Transport Emergency Card: TEC (R)-61GTFC-I ADDITIONAL INFORMATION ICSC: 0287 ISOPROPYL CHLOROFORMATE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.