International Chemical Safety Cards 2-NITROPROPANE ICSC: 0187 Isonitropropane Dimethylnitromethane sec-Nitropropane C3H7NO2 / CH3CHNO2CH3 Molecular mass: 89.1 ICSC #    0187 CAS #     79-46-9 RTECS # TZ5250000 UN #        2608 EC #         609-002-00-1 March 17, 1995 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Flammable. Many reactions may cause fire or explosion. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames, NO sparks, and NO smoking. Powder, alcohol-resistant foam, water spray, carbon dioxide. EXPLOSION Above 24°C explosive vapour/air mixtures may be formed. Above 24°C use a closed system, ventilation, and explosion-proof electrical equipment. In case of fire: keep drums, etc., cool by spraying with water. Combat fire from a sheltered position. EXPOSURE AVOID ALL CONTACT! AVOID EXPOSURE OF (PREGNANT) WOMEN! IN ALL CASES CONSULT A DOCTOR!  •INHALATION Cough. Dizziness. Drowsiness. Headache. Nausea. Vomiting. Weakness. Ventilation, local exhaust, or breathing protection. Refer for medical attention.  •SKIN Protective gloves. Protective clothing. Remove contaminated clothes. Rinse skin with plenty of water or shower.  •EYES Redness. Pain. Face shield or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION (Further see Inhalation). Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Evacuate danger area in case of a large spillage! Consult an expert! Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT wash away into sewer. Personal protection: self-contained breathing apparatus. Fireproof. Separated from strong bases, strong acids, amines . Note: E T symbol R: 45-10-20/22 S: 53-45 UN Hazard Class: 3 UN Packing Group: III SEE IMPORTANT INFORMATION ON BACK ICSC: 0187 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards 2-NITROPROPANE ICSC: 0187 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS OILY LIQUID. PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on burning producing nitrogen oxides . Shock-sensitive compounds are formed with acids, amines, inorganic bases and heavy metal oxides. Reacts with activated carbon causing fire hazard. May be decomposed by the activated carbon in respirator filters. OCCUPATIONAL EXPOSURE LIMITS: TLV: 10 ppm; A3 (confirmed animal carcinogen with unknown relevance to humans); (ACGIH 2004). MAK: Carcinogen category: 2; (DFG 2004). OSHA PEL: TWA 25 ppm (90 mg/m3) NIOSH REL: Ca See Appendix A NIOSH IDLH: Potential occupational carcinogen 100 ppm ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its vapour and by ingestion. INHALATION RISK: A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20°C. EFFECTS OF SHORT-TERM EXPOSURE: The vapour of this substance is irritating to the eyes and the respiratory tract . Exposure far above the OEL could cause liver damage. Exposure at high levels may result in death. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: The substance may have effects on the liver and nervous system , resulting in nausea, vomiting, diarrhea, anorexia and severe headache. This substance is possibly carcinogenic to humans. Animal tests show that this substance possibly causes toxic effects upon human reproduction. PHYSICAL PROPERTIES Boiling point: 120°C Melting point: -93°C Relative density (water = 1): 0.99 Solubility in water, ml/100 ml at 25°C: 1.7 Vapour pressure, kPa at 20°C: 1.7 Relative vapour density (air = 1): 3.1 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.04 Flash point: 24°C c.c. Auto-ignition temperature: 428°C Explosive limits, vol% in air: 2.6-11 Octanol/water partition coefficient as log Pow: 0.93 ENVIRONMENTAL DATA N O T E S Depending on the degree of exposure, periodic medical examination is indicated. The odour warning when the exposure limit value is exceeded is insufficient. NiPar S-20 and NiPar S-30 are trade names. Card has been partly updated in April 2005. See sections Occupational Exposure Limits, Emergency Response. Transport Emergency Card: TEC (R)-30GF1-III NFPA Code: H2; F3; R1 ADDITIONAL INFORMATION ICSC: 0187 2-NITROPROPANE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.