International Chemical Safety Cards MANEB ICSC: 0173 Manganese, ethylenebis(dithiocarbamato) ((1,2-Ethanediylbis(carbamodithioato))(2-))manganese Manganese ethylene-1,2-dithiocarbamate C4H6N2S4•Mn Molecular mass: 265.3 ICSC #    0173 CAS #     12427-38-2 RTECS # OP0700000 UN #        2210 EC #         006-077-00-7 November 27, 2003 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames. NO contact with water. Carbon dioxide, dry powder. NO hydrous agents. NO water. EXPLOSION EXPOSURE PREVENT DISPERSION OF DUST! AVOID ALL CONTACT!  •INHALATION Cough. Sore throat. Local exhaust or breathing protection. Fresh air, rest.  •SKIN Redness. Protective gloves. Protective clothing. Remove contaminated clothes. Rinse and then wash skin with water and soap.  •EYES Redness. Pain. Safety goggles, or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Do not eat, drink, or smoke during work. Rinse mouth. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Do NOT wash away into sewer. Sweep spilled substance into sealable containers. Carefully collect remainder, then remove to safe place. Do NOT let this chemical enter the environment. (Extra personal protection: P2 filter respirator for harmful particles.) Separated from acids, food and feedstuffs . Dry. Well closed. Keep in a well-ventilated room. Store only if stabilized. Do not transport with food and feedstuffs. Marine pollutant. Xi symbol R: 37-43 S: 2-8-24/25-46 UN Hazard Class: 4.2 UN Subsidiary Risks: 4.3 UN Packing Group: III SEE IMPORTANT INFORMATION ON BACK ICSC: 0173 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards MANEB ICSC: 0173 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: YELLOW POWDER OR CRYSTALS PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on contact with acids and moisture producing toxic and flammable gases including hydrogen sulfide and carbon disulfide. OCCUPATIONAL EXPOSURE LIMITS: TLV not established. MAK: Sh; (DFG 2003). ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its aerosol and by ingestion. INHALATION RISK: Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly when dispersed. EFFECTS OF SHORT-TERM EXPOSURE: The substance is irritating to the eyes , the skin and the respiratory tract . EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: Repeated or prolonged contact may cause skin sensitization. The substance may have effects on the kidneys and central nervous system , resulting in kidney impairment and neurologic, neuropsychiatric disorders (manganism). PHYSICAL PROPERTIES Decomposes below melting point at 192-204°C Density: 1.92 g/cm3 Solubility in water: very poor ENVIRONMENTAL DATA The substance is very toxic to aquatic organisms. This substance does enter the environment under normal use. Great care, however, should be given to avoid any additional release, e.g. through inappropriate disposal. N O T E S UN number 2968: Haz class 4.3; Pack Group III; Maneb stabilized against self-heating. Carrier solvents used in commercial formulations may change physical and toxicological properties. Chloroble M, Dithane M 22, Kypman 80, Manebgan, Manesan, Manzate, Polyram M, Rhodianebe, Sopranebe and Trimangol are trade names. Transport Emergency Card: TEC (R)-42S2210 ADDITIONAL INFORMATION ICSC: 0173 MANEB (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.