International Chemical Safety Cards

MALATHION

ICSC: 0172

S-1,2-bis(Ethoxycarbonyl)ethyl O,O-dimethylphosphorodithioate
Butanedioic acid, {(dimethoxyphosphinothioyl)thio}-, diethyl ester
C₁₀H₁₉O₆PS₂
Molecular mass: 330.4

ICSC #    0172
CAS #     121-75-5
RTECS # WM8400000
UN #        3082
EC #         015-041-00-X
March 13, 1995 Peer reviewed

TYPES OF HAZARD/ EXPOSURE	ACUTE HAZARDS/ SYMPTOMS	PREVENTION	FIRST AID/ FIRE FIGHTING
FIRE	Combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.	NO open flames.	Powder, AFFF, foam, carbon dioxide.
EXPLOSION	Risk of fire and explosion if formulations contain flammable/explosive solvents.

EXPOSURE		PREVENT GENERATION OF MISTS! STRICT HYGIENE! AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN!	IN ALL CASES CONSULT A DOCTOR!
•INHALATION	Dizziness. Pupillary constriction. Muscle cramp. Excessive salivation. Sweating. Laboured breathing. Unconsciousness. Symptoms may be delayed (see Notes).	Ventilation, local exhaust, or breathing protection.	Fresh air, rest. Half-upright position. Refer for medical attention.
•SKIN	(Further see Inhalation).	Protective gloves. Protective clothing.	Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.
•EYES		Safety spectacles.	First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.
•INGESTION	Abdominal cramps. Diarrhoea. Nausea. Vomiting. (Further see Inhalation).	Do not eat, drink, or smoke during work. Wash hands before eating.	Rinse mouth. Rest. Refer for medical attention.

SPILLAGE DISPOSAL

STORAGE

PACKAGING & LABELLING

Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT wash away into sewer. (Extra personal protection: A/P2 filter respirator for organic vapour and harmful dust).

Provision to contain effluent from fire extinguishing. Separated from strong oxidants, food and feedstuffs. Keep in a well-ventilated room.

Do not transport with food and feedstuffs.
Marine pollutant.
Xn symbol
R: 22
S: 2-24
UN Hazard Class: 9
UN Packing Group: III

SEE IMPORTANT INFORMATION ON BACK

ICSC: 0172

Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards

MALATHION

ICSC: 0172

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PHYSICAL STATE; APPEARANCE:
CLEAR, YELLOW TO DEEP BROWN (DEPENDING ON THE PURITY) LIQUID , WITH CHARACTERISTIC ODOUR.

PHYSICAL DANGERS:

CHEMICAL DANGERS:
The substance decomposes on heating or on burning producing toxic fumes including phosphorous oxides and sulfur oxides. Reacts violently with strong oxidants. Attacks iron and some other metals, some plastics and rubber.

OCCUPATIONAL EXPOSURE LIMITS:
TLV: 10 mg/m³ (skin) (ACGIH 1994).
OSHA PEL: TWA 15 mg/m³ skin
NIOSH REL: TWA 10 mg/m³ skin
NIOSH IDLH: 250 mg/m³

ROUTES OF EXPOSURE:
The substance can be absorbed into the body by inhalation, through the skin and by ingestion.

INHALATION RISK:
Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying.

EFFECTS OF SHORT-TERM EXPOSURE:
The substance may cause effects on the nervous system , resulting in convulsions, respiratory failure. Cholinesterase inhibitor. Exposure above OEL may result in death. The effects may be delayed. Medical observation is indicated.

EFFECTS OF LONG-TERM OR REPEATED EXPOSURE:
Repeated or prolonged contact may cause skin sensitization. Cholinesterase inhibitor; cumulative effect is possible: see acute hazards/symptoms.

PHYSICAL
PROPERTIES

Boiling point at 0.093 kPa: 156-157°C
Melting point: 3°C
Relative density (water = 1): 1.2
Solubility in water: none

Vapour pressure, Pa at 30°C: 0.0053
Relative vapour density (air = 1): 11.4
Relative density of the vapour/air-mixture at 20°C (air = 1): 1.00
Octanol/water partition coefficient as log Pow: 2.89

ENVIRONMENTAL
DATA

The substance is very toxic to aquatic organisms. This substance may be hazardous to the environment; special attention should be given to honey bees. Avoid release to the environment in circumstances different to normal use.

N O T E S

Depending on the degree of exposure, periodic medical examination is indicated. The symptoms of acute intoxication do not become manifest until before 30 minutes or 1-2 hours. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. If the substance is formulated with solvent(s) also consult the card(s) (ICSC) of the solvent(s). Carrier solvents used in commercial formulations may change physical and toxicological properties. Carbofos, Celthion, Cythion, Emmatos, Fosfothion, Fyfanon, Karbofos, Kypfos, Malamar, Malatol, Malatox, Sadophos, Sumitox, Zithiol are trade names.

ADDITIONAL INFORMATION

ICSC: 0172	MALATHION
(C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE:

Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.