International Chemical Safety Cards 1,4-DICHLOROBENZENE ICSC: 0037 p-Dichlorobenzene PDCB C6H4Cl2 Molecular mass: 147 ICSC #    0037 CAS #     106-46-7 RTECS # CZ4550000 UN #        3077 EC #         602-035-00-2 November 26, 2003 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire. NO open flames. Powder, water spray, foam, carbon dioxide. EXPLOSION Above 66°C explosive vapour/air mixtures may be formed. Above 66°C use a closed system, ventilation, and explosion-proof electrical equipment. In case of fire: keep drums, etc., cool by spraying with water. EXPOSURE AVOID ALL CONTACT!  •INHALATION Burning sensation. Cough. Drowsiness. Headache. Nausea. Shortness of breath. Vomiting. Ventilation, local exhaust, or breathing protection. Fresh air, rest. Refer for medical attention.  •SKIN Protective gloves. Remove contaminated clothes. Rinse and then wash skin with water and soap.  •EYES Redness. Pain. Safety goggles, or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Diarrhoea. (Further see Inhalation). Do not eat, drink, or smoke during work. Give plenty of water to drink. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. Personal protection: filter respirator for organic gases and vapours. Do NOT let this chemical enter the environment. Provision to contain effluent from fire extinguishing. Separated from strong oxidants, food and feedstuffs . Keep in a well-ventilated room. Do not transport with food and feedstuffs. Marine pollutant. Xn symbol N symbol R: 36-40-50/53 S: 2-36/37-46-60-61 UN Hazard Class: 9 UN Packing Group: III SEE IMPORTANT INFORMATION ON BACK ICSC: 0037 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards 1,4-DICHLOROBENZENE ICSC: 0037 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: COLOURLESS TO WHITE CRYSTALS , WITH CHARACTERISTIC ODOUR. PHYSICAL DANGERS: CHEMICAL DANGERS: On combustion, forms toxic and corrosive fumesincludinghydrogen chloride. Reacts with strong oxidants . OCCUPATIONAL EXPOSURE LIMITS: TLV: 10 ppm as TWA; A3; (ACGIH 2004). MAK: H; Carcinogen category: 2; Germ cell mutagen group: 3B; (DFG 2004). OSHA PEL: TWA 75 ppm (450 mg/m3) NIOSH REL: Ca See Appendix A NIOSH IDLH: Potential occupational carcinogen 150 ppm ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation and by ingestion. INHALATION RISK: A harmful contamination of the air will be reached rather slowly on evaporation of this substance at 20°C. EFFECTS OF SHORT-TERM EXPOSURE: The substance is irritating to the eyes and the respiratory tract . The substance may cause effects on the blood , resulting in haemolytic anaemia. The substance may cause effects on the central nervous system. Medical observation is indicated. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: The substance may have effects on the liver, kidneys and blood. This substance is possibly carcinogenic to humans. PHYSICAL PROPERTIES Boiling point: 174°C Melting point: 53°C Density: 1.2 g/cm3 Solubility in water: at 25 °C 80 mg/l Vapour pressure, Pa at 20°C: 170 Relative vapour density (air = 1): 5.08 Relative density of the vapour/air-mixture at 20°C (air = 1): 1.01 Flash point: 66°C c.c. Explosive limits, vol% in air: 6.2-16 Octanol/water partition coefficient as log Pow: 3.37 ENVIRONMENTAL DATA The substance is toxic to aquatic organisms. Bioaccumulation of this chemical may occur in fish. N O T E S Depending on the degree of exposure, periodic medical examination is suggested. Do NOT take working clothes home. Card has been partly updated in October 2004. See sections Occupational Exposure Limits, EU classification, Emergency Response. Transport Emergency Card: TEC (R)-90GM7-III NFPA Code: H 2; F 2; R 0; ADDITIONAL INFORMATION ICSC: 0037 1,4-DICHLOROBENZENE (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.