The Registry of Toxic Effects of Chemical Substances

Benzene, p - dichloro -

RTECS #: CZ4550000

CAS #: 106-46-7

UPDATE: May 2005 MW: 147.00 MF: C6H4Cl2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. MUTATION DATA:
  4. REPRODUCTIVE EFFECTS DATA:
  5. TUMORIGENIC DATA:
  6. ACUTE TOXICITY DATA:
  7. OTHER MULTIPLE DOSE DATA:
  8. REVIEWS:
  9. STANDARDS AND REGULATIONS:
  10. NIOSH DOCUMENTATION AND SURVEILLANCE:
  11. STATUS IN FEDERAL AGENCIES:
  12. REFERENCES:

SYNONYMS:

  1. 1,4 - Dichloorbenzeen (Dutch)
  2. 1,4 - Dichlor - benzol (German)
  3. 1,4 - Dichlorobenzene
  4. 1,4 - Diclorobenzene (Italian)
  5. Di - chloricide
  6. Evola
  7. Globol
  8. NCI - C54955
  9. PDB
  10. PDCB
  11. Para crystals
  12. Paracide
  13. Paradi
  14. Paradichlorbenzol (German)
  15. Paradichlorobenzene
  16. Paradichlorobenzol
  17. Paradow
  1. Paramoth
  2. Paranuggets
  3. Parazene
  4. Persia - perazol
  5. RCRA waste number U070
  6. RCRA waste number U071
  7. RCRA waste number U072
  8. Santochlor
  9. p - Chlorophenyl chloride
  10. p - Dichloorbenzeen (Dutch)
  11. p - Dichlorbenzol (German)
  12. p - Dichlorobenzene
  13. p - Dichlorobenzene (ACGIH:OSHA)
  14. p - Dichlorobenzol
  15. p - Diclorobenzene (Italian)
  16. para - Chlorophenyl chloride
  17. para - Dichlorobenzene


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
eye
human 		80 ppm N/R AMIHAB 14,138,1956


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
DNA damage intraperitoneal
mouse 		2 gm/kg MUREAV 391,201,1997
DNA repair oral
mouse 		1,000 mg/kg TCMUD8 18,309,1998
DNA repair oral
rat 		1,000 mg/kg TCMUD8 18,309,1998
mutation in microorganisms Aspergillus nidulans 200 mg/L (-enzymatic activation step) CJMIAZ 16,369,1970
micronucleus test intraperitoneal
mouse 		355 mg/kg/24 hour MUTAEX 2,111,1987
gene conversion and mitotic recombination Saccharomyes cerevisiae 1 mmol/L MUREAV 413,205,1998
other mutation test systems oral
mouse 		750 mg/kg MUREAV 343,157,1995
sister chromatid exchange human lymphocyte 100 µg/L MUREAV 263,57,1991
sperm morphology intraperitoneal
rat 		800 mg/kg ACDSEL 2,248,1985


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
rabbit 		lowest published toxic concentration: 800 ppm/6 hour (6-18 day pregnant) Reproductive: Specific developmental abnormalities: Cardiovascular (circulatory) system FAATDF 5,190,1985
oral
rat 		lowest published toxic dose: 7,500 mg/kg (6-15 day pregnant) Reproductive: Specific developmental abnormalities: Musculoskeletal system BECTA6 37,164,1986
oral
rat 		lowest published toxic dose: 10 gm/kg (6-15 day pregnant) Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus) BECTA6 37,164,1986


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
mouse 		lowest published toxic dose: 155 gm/kg/2 year- intermittent Tumorigenic: Carcinogenic by RTECS criteria

Liver: Tumors 		NTPTR* NTP-TR-319,1987
oral
mouse 		lowest published toxic dose: 309,000 mg/kg/103 week- intermittent Tumorigenic: Carcinogenic by RTECS criteria

Liver: Tumors 		NTIS** PB87-208617/AS
oral
mouse 		lowest published toxic dose: 309,000 mg/kg/103 week- intermittent Tumorigenic: Equivocal tumorigenic agent by RTECS criteria

Endocrine: Adrenal cortex tumors 		NTIS** PB87-208617/AS
oral
rat 		lowest published toxic dose: 155 gm/kg/2 year- intermittent Tumorigenic: Carcinogenic by RTECS criteria

Kidney, Ureter, and Bladder: Kidney tumors 		NTPTR* NTP-TR-319,1987
oral
rat 		lowest published toxic dose: 77,250 mg/kg/13 week- intermittent Tumorigenic: Carcinogenic by RTECS criteria

Kidney, Ureter, and Bladder: Kidney tumors 		NTIS** PB87-208617/AS


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
cat 		lowest published lethal concentration: 37 gm/m3/30 minute Behavioral: General anesthetic YKYUA6 38,1045,1987
inhalation
human 		lowest published toxic concentration: 480 mg/m3 Eye: Conjunctiva irritation

Olfaction: Other olfaction effects 		VCVGK* -,24,1984
inhalation
mammal (species unspecified) 		lethal concentration (50 percent kill): 12 gm/m3 N/R GTPZAB 32(10),25,1988
inhalation
rat 		lethal concentration (50 percent kill): 5,000 mg/m3/4 hour N/R BFUUA* 185,1,1996
intraperitoneal
mouse 		lethal dose (50 percent kill): 2 gm/kg N/R MUTAEX 2,111,1987
intraperitoneal
rat 		lethal dose (50 percent kill): 2,562 mg/kg N/R JAPMA8 38,124,1949
intraperitoneal
rat 		lowest published toxic dose: 4 mg/kg Liver: Changes in liver weight TXAPA9 111,69,1991
intraperitoneal
rat 		lowest published toxic dose: 1 mg/kg Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis) TXAPA9 111,69,1991
intraperitoneal
rat 		lowest published toxic dose: 2 mg/kg Endocrine: Evidence of thyroid hypofunction TXAPA9 111,69,1991
oral
guinea pig 		lowest published lethal dose: 2,800 mg/kg N/R AMIHAB 14,138,1956
oral
human 		lowest published toxic dose: 300 mg/kg Eye: Other eye effects

Lung, Thorax, or Respiration: Other changes

Gastrointestinal: Hypermotility, diarrhea 		PCOC** -,851,1966
oral
human 		lowest published lethal dose: 857 mg/kg N/R 34ZIAG -,210,1969
oral
mammal (species unspecified) 		lethal dose (50 percent kill): 2,600 mg/kg N/R GTPZAB 32(10),25,1988
oral
mouse 		lethal dose (50 percent kill): 2,950 mg/kg N/R GUCHAZ 6,183,1973
oral
rat 		lethal dose (50 percent kill): 500 mg/kg N/R WRPCA2 9,119,1970
oral
rabbit 		lethal dose (50 percent kill): 2,830 mg/kg N/R YKYUA6 29,453,1978
subcutaneous
mouse 		lethal dose (50 percent kill): 5,145 mg/kg Behavioral: Tremor TOIZAG 20,772,1973
skin
rat 		lethal dose (50 percent kill): 2,000 mg/kg N/R BFUUA* 185,1,1996
skin
rabbit 		lethal dose (50 percent kill): >2 gm/kg N/R SPEADM 78-1,18,1978
unreported route
human 		lowest published lethal dose: 357 mg/kg N/R YKYUA6 31,1499,1980
unreported route
man 		lowest published lethal dose: 221 mg/kg N/R 85DCAI 2,73,1970


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
guinea pig 		lowest published toxic concentration: 158 ppm/7 hour/31 week- intermittent Liver: Changes in liver weight AMIHAB 14,138,1956
inhalation
guinea pig 		lowest published toxic concentration: 100 gm/m3/20 minute/20 day- intermittent Blood: Granulocytopenia

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field 		JAPMA8 38,124,1949
inhalation
rat 		lowest published toxic concentration: 158 ppm/7 hour/31 week- intermittent Liver: Changes in liver weight

Kidney, Ureter, and Bladder: Changes in bladder weight 		AMIHAB 14,138,1956
inhalation
rat 		lowest published toxic concentration: 100 gm/m3/20 minute/25 day- intermittent Behavioral: General anesthetic

Behavioral: Tremor

Blood: Granulocytopenia 		JAPMA8 38,124,1949
inhalation
rat 		lowest published toxic concentration: 140 ppm/6 hour/2 year- intermittent Olfaction: Other olfaction effects

Kidney, Ureter, and Bladder: Other changes 		JTSCDR 22,357,1997
inhalation
rat 		lowest published toxic concentration: 950 mg/m3/7 hour/22 week- intermittent Liver: Other changes VCVGK* -,24,1994
inhalation
rabbit 		lowest published toxic concentration: 100 gm/m3/30 minute/31 day- intermittent Olfaction: Other olfaction effects

Eye: Other eye effects

Blood: Granulocytopenia 		JAPMA8 38,124,1949
oral
mouse 		lowest published toxic dose: 58,500 mg/kg/13 week- intermittent Liver: Hepatitis (hepatocellular necrosis), zonal

Kidney, Ureter, and Bladder: Changes in bladder weight

Blood: Changes in leukocyte (WBC) count 		NTPTR* NTP-TR-319,1987
oral
mouse 		lowest published toxic dose: 3 gm/kg/1 week- intermittent Liver: Other changes

Liver: Changes in liver weight

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) 		FAATDF 39,67,1997
oral
mouse 		lowest published toxic dose: 3 gm/kg/7 day- continuous Liver: Other changes

Liver: Changes in liver weight

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Cytochrome oxidases (indlucing oxidative phosphrylation) 		EVHPAZ 110,363,2002
oral
rat 		lowest published toxic dose: 14 gm/kg/14 day- intermittent Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field NTPTR* NTP-TR-319,1987
oral
rat 		lowest published toxic dose: 58,500 mg/kg/13 week- intermittent Liver: Changes in liver weight

Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis)

Blood: Changes in erythrocyte (RBC) count 		NTPTR* NTP-TR-319,1987
oral
rat 		lowest published toxic dose: 10 gm/kg/4 week- intermittent Liver: Hepatitis (hepatocellular necrosis), zonal

Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis) 		AMIHAB 14,138,1956
oral
rat 		lowest published toxic dose: 750 mg/kg/7 day- continuous Kidney, Ureter, and Bladder: Other changes

Kidney, Ureter, and Bladder: Changes in kidney weight 		EVHPAZ 110,363,2002
oral
rat 		lowest published toxic dose: 9 gm/kg/90 day- continuous Liver: Other changes

Liver: Changes in liver weight

Kidney, Ureter, and Bladder: Changes in kidney weight 		EVHPAZ 110,363,2002
oral
rat 		lowest published toxic dose: 18 gm/kg/90 day- continuous Liver: Other changes

Liver: Changes in liver weight 		EVHPAZ 110,363,2002
oral
rat 		lowest published toxic dose: 90 mg/kg/3 day- intermittent Kidney, Ureter, and Bladder: Other changes

Biochemical: Metabolism (intermediary): Other proteins 		TXCYAC 180,233,2002
oral
rabbit 		lowest published toxic dose: 92 gm/kg/31 week- intermittent Behavioral: Tremor

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field 		AMIHAB 14,138,1956


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 10 ppm DTLVS* TLV/BEI,2003
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value Confirmed Animal Carcinogen with Unknown DTLVS* TLV/BEI,2003
International Agency for Research on Cancer (IARC) Cancer Review Animal Sufficient Evidence IMSUDL 7,192,1987
International Agency for Research on Cancer (IARC) Cancer Review Animal Sufficient Evidence IMEMDT 73,223,1999
International Agency for Research on Cancer (IARC) Cancer Review Human Inadequate Evidence IMEMDT 7,231,1974
International Agency for Research on Cancer (IARC) Cancer Review Animal Inadequate Evidence IMEMDT 7,231,1974
International Agency for Research on Cancer (IARC) Cancer Review Human Inadequate Evidence IMEMDT 29,213,1982
International Agency for Research on Cancer (IARC) Cancer Review Animal Inadequate Evidence IMEMDT 29,213,1982
International Agency for Research on Cancer (IARC) Cancer Review Human Inadequate Evidence IMEMDT 73,223,1999
International Agency for Research on Cancer (IARC) Cancer Review Group 2B IMEMDT 73,223,1999
TOXICOLOGY REVIEW
TOLED5 127,111,2002
TOXICOLOGY REVIEW
MUREAV 543,201,2003
TOXICOLOGY REVIEW
MUREAV 5432012003


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES: Supported RBREV* -,250,1998
Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 75 ppm (450 mg/m3) DTLVS* 3,77,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 75 ppm (450 mg/m3) CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 75 ppm (450 mg/m3) CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 75 ppm (450 mg/m3) CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 75 ppm (450 mg/m3) CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - AUSTRALIA time-weighted average 75 ppm (450 mg/m3), short term exposure limit 110 ppm, JAN1993
Occupational Exposure Limit - AUSTRIA Carcinogen, JAN1999
Occupational Exposure Limit - BELGIUM time-weighted average 75 ppm (451 mg/m3), short term exposure limit 110 ppm (661 mg/m3), JAN1993
Occupational Exposure Limit - FINLAND time-weighted average 75 ppm (450 mg/m3), short term exposure limit 115 ppm (690 mg/m3), Skin, JAN1999
Occupational Exposure Limit - FRANCE VME 75 ppm (450 mg/m3), VLE 110 ppm (675 mg/m3), JAN1999
Occupational Exposure Limit - GERMANY MAK 50 ppm (300 mg/m3), JAN1999
Occupational Exposure Limit - JAPAN Occupational Exposure Limit 50 ppm (300 mg/m3), 2B Carcinogen, JAN1999
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 150 mg/m3, 2003
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 75 ppm (450 mg/m3), JAN1993
Occupational Exposure Limit - POLAND MAC(time-weighted average) 20 mg/m3, JAN1999
Occupational Exposure Limit - RUSSIA time-weighted average 50 ppm, JAN1993
Occupational Exposure Limit - SWEDEN NGV 75 ppm (450 mg/m3), KTV 110 ppm (700 mg/m3), JAN1999
Occupational Exposure Limit - SWITZERLAND MAK- week 50 ppm (300 mg/m3), KZG- week 100 ppm (600 mg/m3),JAN1999
Occupational Exposure Limit - TURKEY time-weighted average 75 ppm (450 mg/m3), JAN1993
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 25 ppm (153 mg/m3), short term exposure limit 50 ppm (306 mg/m3), SEP2000
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

Confirmed Animal Carcinogen with Unknown
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
Confirmed Animal Carcinogen with Unknown


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO p-DICHLOROBENZENE-air Carcinogen (1.7 ppm LOQ) NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 24006;
Number of Industries 21;
Total Number of Facilities 1,963;
Number of Occupations 18;
Total Number of Employees Exposed 23,116
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 24006;
Number of Industries 22;
Total Number of Facilities 2,629;
Number of Occupations 21;
Total Number of Employees Exposed 33,978;
Total Number of Female Employees Exposed 9,412


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
ATSDR TOXICOLOGY PROFILE (NTIS** PB/99/121972)
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA 8(a) PRELIMINARY ASSESSMENT INFORMATION, FINAL RULE FEREAC 47,26992,82
Used as a moth repellant, a mildew control agent and a space deodorant
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA Section 8(e) Risk Notification, 8EHQ-0892-9004
On EPA IRIS database
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Hydrocarbons, halogenated, 1003
NIOSH Analytical Method, 1996: Volatile organic compound, 2549
NCI Carcinogenesis Studies (gavage);clear evidence:mouse,rat
NTP 11th Report on Carcinogens,2004:Reasonably anticipated to be a human carcinogen


REFERENCES:

CODEN
REFERENCE
34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969
85DCAI "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970
ACDSEL Advances in Contraceptive Delivery Systems. (Reproductive Health Center, 78 Surfsong Rd., Kiawah Island, SC 29455) V.1- 1985-
AMIHAB AMA Archives of Industrial Health. (Chicago, IL) V.11-21, 1955-60. For publisher information, see AEHLAU.
BECTA6 Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1966-
BFUUA* Beratergremium fuer umweltrelevante Altstoffe (BUA. Gesellschaft Deutscher Chemiker. Weinheim ; New York : VCH) 1992-
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
CJMIAZ Canadian Journal of Microbiology. (National Research Council of Canada, Publication Sales and Distribution, Ottawa ON K1A OR6, Canada) V.1- 1954-
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972-
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1-40, 1981-97. For publisher information, see TOSCF2
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI
GUCHAZ Guide to the Chemicals Used in Crop Protection. (Information Canada, 171 Slater St., Ottawa, Ont., Canada)
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972-
IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979-
JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE.
JTSCDR Journal of Toxicological Sciences. (Japanese Soc. of Toxicological Sciences, 4th Floor, Gakkai Center Bldg., 4-16, Yayoi 2-chome, Bunkyo-ku, Tokyo 113, Japan) V.1- 1976-
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986-
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206-
PCOC** Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. (Topeka, KS)
RBREV* Status of Pesticides in Registration, Reregistration, and Special Review (Rainbow Report), Special Review and Reregistration Division Office of Pesticide Programs U.S. Environmental Protection Agency, 401 M. Street, S.W., Washington, D.C. 20460, Spring 1998
SPEADM Special Publication of the Entomological Society of America. (4603 Calvert Rd., College Park, MD 20740)
TCMUD8 Teratogenesis, Carcinogenesis, and Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1980-
TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954-
TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977-
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-
TXCYAC Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973-
VCVGK* "Vrednie chemichescie veshestva, galogen I kislorod sodergashie organicheskie soedinenia". (Hazardous substances. Galogen and oxygen containing substances), Bandman A.L. et al., Chimia, 1994.
WRPCA2 World Review of Pest Control. (London, UK) V.1-10, 1962-71. Discontinued.
YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950-

Used as a moth repellant, a mildew control agent and a space deodorant

RTECS Compound Description:
   Agricultural Chemical
   Tumorigen
   Mutagen
   Reproductive Effector
   Human Data
   Primary Irritant

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