International Chemical Safety Cards 2,4-D ICSC: 0033 2,4-Dichlorophenoxyacetic acid C8H6Cl2O3 Molecular mass: 221.0 ICSC #    0033 CAS #     94-75-7 RTECS # AG6825000 UN #        2765 EC #         607-039-00-8 April 22, 1994 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Not combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire. NO contact with oxidants. In case of fire in the surroundings: all extinguishing agents allowed. EXPLOSION Risk of fire and explosion if formulations contain flammable/explosive solvents. EXPOSURE PREVENT DISPERSION OF DUST! STRICT HYGIENE! AVOID EXPOSURE OF (PREGNANT) WOMEN!  •INHALATION Headache. Nausea. Weakness. Local exhaust or breathing protection. Fresh air, rest. Refer for medical attention.  •SKIN Redness. Protective gloves. Protective clothing. Remove contaminated clothes. Rinse and then wash skin with water and soap.  •EYES Redness. Safety goggles, or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Abdominal pain. Burning sensation. Diarrhoea. Headache. Nausea. Unconsciousness. Vomiting. Weakness. Do not eat, drink, or smoke during work. Wash hands before eating. Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer for medical attention. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Sweep spilled substance into sealable containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place. (Extra personal protection: P2 filter respirator for harmful particles). Separated from strong oxidants, food and feedstuffs . Do not transport with food and feedstuffs. Marine pollutant. Xn symbol R: 22-36/37/38 S: 2-36/37 UN Hazard Class: 6.1 UN Packing Group: III SEE IMPORTANT INFORMATION ON BACK ICSC: 0033 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards 2,4-D ICSC: 0033 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: ODOURLESS, COLOURLESS CRYSTALS OR WHITE POWDER. PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on heating producing hydrogen chloride and phosgene . The substance is a weak acid. Reacts with strong oxidants causing fire and explosion hazard. OCCUPATIONAL EXPOSURE LIMITS: TLV: 10 mg/m3 (as TWA) (ACGIH 1993-1994). OSHA PEL: TWA 10 mg/m3 NIOSH REL: TWA 10 mg/m3 NIOSH IDLH: 100 mg/m3 ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its aerosol, through the skin and by ingestion. INHALATION RISK: Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying or when dispersed, especially if powdered. EFFECTS OF SHORT-TERM EXPOSURE: The substance irritates the eyes, the skin and the respiratory tract. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: Animal tests show that this substance possibly causes toxic effects upon human reproduction (see Notes). PHYSICAL PROPERTIES Decomposes below boiling point Melting point: 138°C Relative density (water = 1): 1.6 Solubility in water: none Octanol/water partition coefficient as log Pow: 2.81 ENVIRONMENTAL DATA The substance is harmful to aquatic organisms. N O T E S 2,4-D is a chlorophenoxy-herbicide which, as a group, has been classified as possibly carcinogenic to humans. Depending on the degree of exposure, periodic medical examination is indicated. Carrier solvents used in commercial formulations may change physical and toxicological properties. Transport Emergency Card: TEC (R)-61G53c ADDITIONAL INFORMATION ICSC: 0033 2,4-D (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.