International Chemical Safety Cards PARATHION ICSC: 0006 O,O-Diethyl-O-(4-nitrophenyl)phosphorothioate Phosphorothioic acid O,O-diethyl O-(4-nitrophenyl) ester Ethyl parathion (C2H5O)2PSOC6H4NO2 Molecular mass: 291.3 ICSC #    0006 CAS #     56-38-2 RTECS # TF4550000 UN #        3018 EC #         015-034-00-1 April 22, 2004 Peer reviewed TYPES OF HAZARD/ EXPOSURE ACUTE HAZARDS/ SYMPTOMS PREVENTION FIRST AID/ FIRE FIGHTING FIRE Combustible. Gives off irritating or toxic fumes (or gases) in a fire. Liquid formulations containing organic solvents may be flammable. NO open flames. Water spray, dry powder, carbon dioxide. EXPLOSION In case of fire: keep drums, etc., cool by spraying with water. EXPOSURE PREVENT GENERATION OF MISTS! STRICT HYGIENE! AVOID EXPOSURE OF ADOLESCENTS AND CHILDREN! IN ALL CASES CONSULT A DOCTOR!  •INHALATION Pupillary constriction, muscle cramp, excessive salivation. Sweating. Nausea. Vomiting. Dizziness. Headache. Convulsions. Diarrhoea. Weakness. Laboured breathing. Wheezing. Unconsciousness. Ventilation, local exhaust, or breathing protection. Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.  •SKIN MAY BE ABSORBED! (Further see Inhalation). Protective gloves. Protective clothing. Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention.  •EYES MAY BE ABSORBED! Redness. Pain. Blurred vision. Face shield, or eye protection in combination with breathing protection. First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then take to a doctor.  •INGESTION Abdominal cramps. Diarrhoea. Vomiting. (Further see Inhalation). Do not eat, drink, or smoke during work. Wash hands before eating. Give a slurry of activated charcoal in water to drink. Refer for medical attention. See Notes. SPILLAGE DISPOSAL STORAGE PACKAGING & LABELLING Evacuate danger area! Consult an expert! Collect leaking and spilled liquid in sealable containers as far as possible. Treat remaining liquid with an alkaline substance. Absorb remaining liquid in sand or inert absorbent and remove to safe place. Do NOT let this chemical enter the environment. Personal protection: chemical protection suit including self-contained breathing apparatus. Provision to contain effluent from fire extinguishing. Separated from strong oxidants, food and feedstuffs . Well closed. Keep in a well-ventilated room. Do not transport with food and feedstuffs. Severe marine pollutant. T+ symbol N symbol R: 24-26/28-48/25-50/53 S: 1/2-28-36/37-45-60-61 UN Hazard Class: 6.1 UN Packing Group: I SEE IMPORTANT INFORMATION ON BACK ICSC: 0006 Prepared in the context of cooperation between the International Programme on Chemical Safety & the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH values.

International Chemical Safety Cards PARATHION ICSC: 0006 I M P O R T A N T D A T A PHYSICAL STATE; APPEARANCE: PALE YELLOW TO BROWN (TECHNICAL PRODUCT) LIQUID , WITH CHARACTERISTIC ODOUR. PHYSICAL DANGERS: CHEMICAL DANGERS: The substance decomposes on heating above 200°C, producing toxic gases including carbon monoxide , nitrogen oxides , phosphorous oxides and sulfur oxides . Reacts with strong oxidants. Attacks some forms of plastics, rubber and coatings. OCCUPATIONAL EXPOSURE LIMITS: TLV: (I,V) 0.05 mg/m³; A4; BEI issued; (skin); (ACGIH 2004). MAK: (I) 0.1 mg/m³; H; Peak limitation category: II (8); Pregnancy risk group: D; (DFG 2003). OSHA PEL: TWA 0.1 mg/m3 skin NIOSH REL: TWA 0.05 mg/m3 skin NIOSH IDLH: 10 mg/m3 ROUTES OF EXPOSURE: The substance can be absorbed into the body by inhalation of its aerosol, through the skin, by ingestion and through the eyes. INHALATION RISK: Evaporation at 20°C is negligible; a harmful concentration of airborne particles can, however, be reached quickly on spraying. EFFECTS OF SHORT-TERM EXPOSURE: The substance may cause effects on the nervous system , resulting in convulsions, respiratory failure, muscle weakness. Cholinesterase inhibition. Exposure may result in death. The effects may be delayed. Medical observation is indicated. EFFECTS OF LONG-TERM OR REPEATED EXPOSURE: Cholinesterase inhibitor; cumulative effect is possible: see acute hazards/symptoms. PHYSICAL PROPERTIES Boiling point: 375°C Melting point: 6°C Relative density (water = 1): 1.26 Solubility in water, g/100 ml at 25°C: 0.002 Flash point: 120°C Octanol/water partition coefficient as log Pow: 3.8 ENVIRONMENTAL DATA The substance is very toxic to aquatic organisms. This substance may be hazardous in the environment; special attention should be given to birds. The substance may cause long-term effects in the aquatic environment. This substance does enter the environment under normal use. Great care, however, should be given to avoid any additional release, e.g. through inappropriate disposal. N O T E S Depending on the degree of exposure, periodic medical examination is indicated. Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available. If the substance is formulated with solvents also consult the ICSCs of these materials. Carrier solvents used in commercial formulations may change physical and toxicological properties. The odour warning when the exposure limit value is exceeded is insufficient. Do NOT take working clothes home. Transport Emergency Card: TEC (R)-61GT6-I ADDITIONAL INFORMATION ICSC: 0006 PARATHION (C) IPCS, CEC, 1994

IMPORTANT LEGAL NOTICE: Neither NIOSH, the CEC or the IPCS nor any person acting on behalf of NIOSH, the CEC or the IPCS is responsible for the use which might be made of this information. This card contains the collective views of the IPCS Peer Review Committee and may not reflect in all cases all the detailed requirements included in national legislation on the subject. The user should verify compliance of the cards with the relevant legislation in the country of use. The only modifications made to produce the U.S. version is inclusion of the OSHA PELs, NIOSH RELs and NIOSH IDLH values.