The Registry of Toxic Effects of Chemical Substances

Zinc phosphide

RTECS #: ZH4900000

CAS #: 1314-84-7

UPDATE: May 2005 MW: 258.05 MF: P2Zn3


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. MUTATION DATA:
  3. ACUTE TOXICITY DATA:
  4. OTHER MULTIPLE DOSE DATA:
  5. STANDARDS AND REGULATIONS:
  6. NIOSH DOCUMENTATION AND SURVEILLANCE:
  7. STATUS IN FEDERAL AGENCIES:
  8. REFERENCES:

SYNONYMS:

  1. Trizinc diphosphide
  2. Blue - OX
  3. Gopha - rid
  4. Kilrat
  5. Mous - Con
  6. Phosphure de zinc (French)
  7. Phosvin
  8. RCRA waste number P122
  1. Rumetan
  2. Zinco (fosfuro di) (Italian)
  3. Zinc (phosphure de) (French)
  4. Zinc - Tox
  5. Zinkphosphid (German)
  6. ZP
  7. Zinkfosfide (Dutch)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
mutation in mammalian somatic cells mouse other cell types 10 mg/L (+/-enzymatic activation step) FEREAC 68,40939,2003


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intraperitoneal
mouse 		lethal dose (50 percent kill): 263 mg/kg N/R GTPZAB 31(9),24,1987
intraperitoneal
rat 		lethal dose (50 percent kill): 450 mg/kg N/R GTPZAB 31(9),24,1987
intratracheal
rat 		lowest published lethal dose: 127.5 mg/kg N/R VCVN5* -,68,1993
oral
wild bird 		lethal dose (50 percent kill): 23,700 µg/kg N/R AECTCV 12,355,1983
oral
cat 		lowest published lethal dose: 40 mg/kg N/R YKYUA6 28,329,1977
oral
duck 		lethal dose (50 percent kill): 37,500 µg/kg N/R 85JFAN A421,1984
oral
dog 		lowest published lethal dose: 40 mg/kg N/R YKYUA6 27,189,1976
oral
domestic animal 		lethal dose (50 percent kill): 60 mg/kg N/R PEMNDP 9,865,1991
oral
mouse 		lethal dose (50 percent kill): 40 mg/kg Behavioral: Somnolence (general depressed activity)

Lung, Thorax, or Respiration: Respiratory depression 		YKYUA6 31,1247,1980
oral
quail 		lethal dose (50 percent kill): 13,500 µg/kg N/R 85JFAN A421,1984
oral
rat 		lethal dose (50 percent kill): 12 mg/kg Gastrointestinal: Other changes MAGJAL 52(2),166,1979
oral
rat 		lethal dose (50 percent kill): 40.5 mg/kg Spinal Cord: Other degenerative changes

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other esterases 		HBPTO* 2,1365,2001
oral
rat 		lethal dose (50 percent kill): 46 mg/kg N/R VCVN5* -,68,1993
oral
rabbit 		lowest published lethal dose: 40 mg/kg Lung, Thorax, or Respiration: Respiratory depression

Lung, Thorax, or Respiration: Respiratory stimulation 		JAPMA8 41,468,1952
oral
woman 		lowest published lethal dose: 80 mg/kg Gastrointestinal: Nausea or vomiting ZACCAL 23,144,1948
oral
woman 		lowest published toxic dose: 3.6 gm/kg Cardiac: Change in force of contraction

Gastrointestinal: Nausea or vomiting

Nutritional and Gross Metabolic: Body temperature decrease 		HBPTO* 2,1366,2001
skin
rabbit 		lethal dose (50 percent kill): 2 gm/kg N/R 85JFAN A421,1984
skin
rabbit 		lowest published toxic dose: 2,000 mg/kg Nutritional and Gross Metabolic: Weight loss or decreased weight gain FEREAC 63,45179,1998
unreported route
man 		lowest published lethal dose: 40 mg/kg N/R AJPEAG 36,1427,1946
unreported route
rat 		lethal dose (50 percent kill): 45 mg/kg N/R YKYUA6 30,397,1979


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
rat 		lowest published toxic concentration: 1 mg/m3/17 week- intermittent Cardiac: Pulse rate increased without fall in BP

Blood: Pigmented or nucleated red blood cells

Nutritional and Gross Metabolic: Weight loss or decreased weight gain 		GTPZAB 31(9),24,1987
inhalation
rat 		lowest published toxic concentration: 1 mg/m3/24 hour/17 week- continuous Behavioral: Altered sleep time (including change in righting reflex)

Cardiac: Pulse rate increased without fall in BP

Blood: Normocytic anemia 		VCVN5* -,68,1989
oral
rat 		lowest published toxic dose: 910 mg/kg/13 week- continuous Behavioral: Food intake (animal)

Nutritional and Gross Metabolic: Weight loss or decreased weight gain

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field 		IJEBA6 18,854,1980
oral
rat 		lowest published toxic dose: 90 mg/kg/90 day- intermittent Kidney, Ureter, and Bladder: Other changes

Liver: Changes in liver weight

Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field 		FEREAC 68,56189,2003
oral
rat 		lowest published toxic dose: 16 mg/kg/4 day- intermittent Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field FEREAC 68,56189,2003


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES: RED Completed RBREV* -,156,1998
Occupational Exposure Limit - RUSSIA time-weighted average 0.1 mg/m3, JAN1993


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X2920;
Number of Industries 3;
Total Number of Facilities 275;
Number of Occupations 3;
Total Number of Employees Exposed 3,862;
Total Number of Female Employees Exposed 48


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as an acute single feeding rodenticide
On EPA IRIS database


REFERENCES:

CODEN
REFERENCE
85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc. of Chemistry, 1983-86
AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973-
AJPEAG American Journal of Public Health and the Nation's Health. (New York, NY) V.18-60, 1928-70. For publisher information, see AJHEAA.
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI
HBPTO* Handbook of pesticide toxicology. Robert Krieger ed, Academic press, 2001
IJEBA6 Indian Journal of Experimental Biology. (Publications & Information Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963-
JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE.
MAGJAL Malaysian Agricultural Journal. (Ministry of Agriculture, Kuala Lumpur, Malaysia) V.45- 1965-
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968-
RBREV* Status of Pesticides in Registration, Reregistration, and Special Review (Rainbow Report), Special Review and Reregistration Division Office of Pesticide Programs U.S. Environmental Protection Agency, 401 M. Street, S.W., Washington, D.C. 20460, Spring 1998
VCVN5* "Vrednie chemichescie veshestva. Neorganicheskie soedinenia elementov V-VII groopp" (Hazardous substances. Inornanic substances containing V-VII group elements), Bandman A.L. et al., Chimia, 1989.
YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950-
ZACCAL Zacchia. Archivio di Medicina Legale, Sociale e Criminologica. Zacchia. Archives of Forensic, Social and Criminological Medicine. (Viale Regina Elena 336, Rome 00161, Italy) V.1-13, 1921-34; V.1- 1937-

Used as an acute single feeding rodenticide

RTECS Compound Description:
   Agricultural Chemical
   Mutagen
   Reproductive Effector
   Human Data

ALT CAS #: 39342-49-9
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