The Registry of Toxic Effects of Chemical Substances

Triphosphoric acid, pentasodium salt

RTECS #: YK4570000

CAS #: 7758-29-4

UPDATE: August 2003 MW: 367.86 MF: O10P3•5Na


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. ACUTE TOXICITY DATA:
  4. OTHER MULTIPLE DOSE DATA:
  5. STANDARDS AND REGULATIONS:
  6. NIOSH DOCUMENTATION AND SURVEILLANCE:
  7. STATUS IN FEDERAL AGENCIES:
  8. REFERENCES:

SYNONYMS:

  1. S 400
  2. Armofos
  3. Empiphos stp - D
  4. Freez - Gard FP 19
  5. Natriumtripolyphosphat (German)
  6. Pentasodium triphosphate
  7. Pentasodium tripolyphosphate
  8. Polygon
  9. Rhodiaphos H 5
  10. Rhodiaphos LV
  11. S 400 (phosphate)
  1. Sodium phosphate (Na5P3O10)
  2. Sodium triphosphate
  3. Sodium triphosphate (Na5P3O10)
  4. Sodium tripolyphosphate
  5. STPP
  6. Thermphos
  7. Thermphos L 50
  8. Thermphos N
  9. Thermphos SPR
  10. Tripoly


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
skin
rabbit 		500 mg/24 hour moderate NTIS** OTS0571941


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intraperitoneal
mouse 		lethal dose (50 percent kill): 700 mg/kg Kidney, Ureter, and Bladder: Changes in tubules (including acute renal failure, acute tubular necrosis) REPMBN 10,391,1962
intraperitoneal
rat 		lethal dose (50 percent kill): 525 mg/kg Behavioral: Excitement

Nutritional and Gross Metabolic: Weight loss or decreased weight gain 		JPETAB 108,117,1953
intravenous
mouse 		lethal dose (50 percent kill): 71 mg/kg N/R ARZNAD 7,445,1957
oral
mouse 		lethal dose (50 percent kill): 3,100 mg/kg Peripheral Nerve and Sensation: Flaccid paralysis without anesthesia (usually neuromuscular blockage)

Behavioral: Somnolence (general depressed activity)

Behavioral: Convulsions or effect on seizure threshold 		GISAAA 38(9),19,1973
oral
rat 		lethal dose (50 percent kill): 3,120 mg/kg Behavioral: Somnolence (general depressed activity)

Behavioral: Coma 		NTIS** OTS0545589
subcutaneous
guinea pig 		lethal dose (50 percent kill): 750 mg/kg N/R VLUBB6 (3),97,1984
subcutaneous
mouse 		lethal dose (50 percent kill): 900 mg/kg N/R ARZNAD 7,445,1957
subcutaneous
rat 		lethal dose (50 percent kill): 2,060 mg/kg N/R VLUBB6 (3),97,1984
skin
rabbit 		lethal dose (50 percent kill): >4,640 mg/kg Behavioral: Somnolence (general depressed activity)

Lung, Thorax, or Respiration: Dyspnea 		NTIS** OTS0571941


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
rat 		lowest published toxic dose: 2,730 mg/kg/13 week- intermittent Endocrine: Changes in spleen weight GISAAA 38(9),19,1973


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES: Cancelled RBREV* -,319,1998


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 80076;
Number of Industries 308;
Total Number of Facilities 101,624;
Number of Occupations 153;
Total Number of Employees Exposed 930,493
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 80076;
Number of Industries 268;
Total Number of Facilities 49,146;
Number of Occupations 169;
Total Number of Employees Exposed 943,961;
Total Number of Female Employees Exposed 347,961


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used in the production of detergents, also used in a variety of processing operations
EPA TSCA Section 8(e) Risk Notification, 8EHQ-0892-8786;8EHQ-0892-8869
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951-
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10-
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.
RBREV* Status of Pesticides in Registration, Reregistration, and Special Review (Rainbow Report), Special Review and Reregistration Division Office of Pesticide Programs U.S. Environmental Protection Agency, 401 M. Street, S.W., Washington, D.C. 20460, Spring 1998
REPMBN Revue d'Epidemiologie, Medecine Sociale et Sante Publique. (Masson Editeur, 120 Blvd. Saint-Germain, F-75280 Paris Cedex O6, France) V.1- 1953-
VLUBB6 Vestnik Leningradskogo Universiteta, Biologiya. Journal of Leningrad University, Biology. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) No.1- 1956-

Used in the production of detergents, also used in a variety of processing operations

NIOSH PROFILE (SODIUM TRIPOLYPHOSPHATE), SRC, 4/81

RTECS Compound Description:
   Primary Irritant

ALT CAS #: 9010-08-6
ALT CAS #: 187620-23-1
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