The Registry of Toxic Effects of Chemical Substances

s - Triazole

RTECS #: XZ3806000

CAS #: 288-88-0

UPDATE: October 1997 MW: 69.08 MF: C2H3N3


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. ACUTE TOXICITY DATA:
  4. OTHER MULTIPLE DOSE DATA:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. TA
  1. 1H - 1,2,4 - Triazole (9CI)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
eye
rabbit 		12% GISAAA 51(11),65,1986
skin
rabbit 		25% GISAAA 51(11),65,1986


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
mouse 		lethal dose (50 percent kill): 1,350 mg/kg Behavioral: Tremor

Behavioral: Excitement

Lung, Thorax, or Respiration: Respiratory depression 		GISAAA 51(11),65,1986
oral
quail 		lethal dose (50 percent kill): >316 mg/kg N/R EESADV 6,149,1982
oral
rat 		lethal dose (50 percent kill): 1,750 mg/kg Behavioral: Tremor

Behavioral: Excitement

Lung, Thorax, or Respiration: Respiratory depression 		GISAAA 51(11),65,1986


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
rat 		lowest published toxic dose: 364 mg/kg/26 week- intermittent Brain and Coverings: Recordings from specific areas of CNS

Kidney, Ureter, and Bladder: Proteinuria 		GISAAA 51(11),65,1986


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
N/R N/R N/R


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
EESADV Ecotoxicology and Environmental Safety. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1977-
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-

RTECS Compound Description:
   Drug
   Primary Irritant

ALT CAS #: 288-89-1
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