The Registry of Toxic Effects of Chemical Substances
s - Triazine - 2,4,6 (1H,3H,5H) - trione, dichloro - , sodium salt |
UPDATE: August 2003 | MW: 220.96 | MF: C3HCl2N3O3•Na |
SYNONYMS:
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SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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eye | rabbit
10 mg/24 hour rinse
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moderate
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MONS** -,-,1972
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eye | rabbit
100 mg/24 hour
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mild
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NTIS** OTS0555174
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skin | rabbit
500 mg/24 hour
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mild
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MONS** -,-,1972
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skin | rabbit
500 mg
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severe
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34ZIAG -,167,1969
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MUTATION DATA AND REFERENCES:
SYSTEM TEST
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ROUTE/ | ORGANISM/ TISSUE
DOSE
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REFERENCE
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N/R
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N/R
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N/R
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N/R
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REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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oral | mouse
lowest published toxic dose: 4 gm/kg (6-15 day pregnant)
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Reproductive: Specific developmental abnormalities: Musculoskeletal system | Reproductive: Effects on newborn: Physical
YKRYAH 13,353,1980
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oral | mouse
lowest published toxic dose: 4 gm/kg (6-15 day pregnant)
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Reproductive: Specific developmental abnormalities: Musculoskeletal system | Reproductive: Effects on newborn: Growth statistics (e.g., reduced weight gain) Reproductive: Effects on newborn: Physical
YKRYAH 13,23,1980
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TUMORIGENIC DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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N/R |
N/R
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N/R
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N/R
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ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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oral | human
lowest published lethal dose: 3,570 mg/kg
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Gastrointestinal: Ulceration or bleeding from stomach
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34ZIAG -,167,1969
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oral | mammal (species unspecified)
lethal dose (50 percent kill): 1,670 mg/kg
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N/R
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YKYUA6 31,959,1980
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oral | rat
lethal dose (50 percent kill): 1,420 mg/kg
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Behavioral: Somnolence (general depressed activity) | Lung, Thorax, or Respiration: Acute pulmonary edema Liver: Other changes
NTIS** OTS0555174
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oral | rabbit
lowest published lethal dose: 2,500 mg/kg
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Eye: Lacrimation | Behavioral: Coma Lung, Thorax, or Respiration: Dyspnea
MONS** -,-,1972
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skin | rabbit
lowest published lethal dose: 3,160 mg/kg
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Behavioral: Somnolence (general depressed activity) | Lung, Thorax, or Respiration: Pulmonary emboli Liver: Other changes
NTIS** OTS0555174
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OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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N/R |
N/R
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N/R
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N/R
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REVIEWS:
ORGANIZATION
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STANDARD
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REFERENCE
N/R
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N/R
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N/R
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STANDARDS AND REGULATIONS:
ORGANIZATION
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STANDARD
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REFERENCE
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988
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PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
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FEREAC 54,7740,1989
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Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF
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PESTICIDES: RED Completed
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RBREV* -,97,1998
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NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION
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STANDARD or SURVEY
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REFERENCE
National Occupational Hazard Survey 1974
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National Occupational Hazard Survey 1974: Hazard Code: M1492; | Number of Industries 29; Total Number of Facilities 6,526; Number of Occupations 27; Total Number of Employees Exposed 39,204
National Occupational Exposure Survey 1983
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National Occupational Exposure Survey 1983: Hazard Code: M1492; |
Number of Industries 33; Total Number of Facilities 3,499; Number of Occupations 38; Total Number of Employees Exposed 53,851; Total Number of Female Employees Exposed 24,172 |
STATUS IN FEDERAL AGENCIES:
ORGANIZATION
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REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
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Used in cleaning, bleaching, disinfecting, sanitizing
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EPA TSCA Section 8(e) Risk Notification, 8EHQ-0892-9201
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EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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REFERENCES:
CODEN
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REFERENCE
34ZIAG
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"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969
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FEREAC
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Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
V.1- 1936-
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MONS**
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Monsanto Co. Toxicity Information. (Monsanto Industrial Chemicals Co., Bancroft Bldg., Suite
204, 3411 Silverside Rd., Wilmington, DE 19810)
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NTIS**
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National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information.
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RBREV*
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Status of Pesticides in Registration, Reregistration, and Special Review (Rainbow Report),
Special Review and Reregistration Division Office of Pesticide Programs U.S. Environmental
Protection Agency, 401 M. Street, S.W., Washington, D.C. 20460, Spring 1998
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YKRYAH
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Yakubutsu Ryoho. Medicinal Treatment. (Tokyo, Japan) V.1-14, 1968-81. Suspended.
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YKYUA6
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Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950-
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