The Registry of Toxic Effects of Chemical Substances

Toxaphene

RTECS #: XW5250000

CAS #: 8001-35-2

UPDATE: May 2005 MW: 413.80 MF: C10H10Cl8


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. MUTATION DATA:
  4. REPRODUCTIVE EFFECTS DATA:
  5. TUMORIGENIC DATA:
  6. ACUTE TOXICITY DATA:
  7. OTHER MULTIPLE DOSE DATA:
  8. REVIEWS:
  9. STANDARDS AND REGULATIONS:
  10. NIOSH DOCUMENTATION AND SURVEILLANCE:
  11. STATUS IN FEDERAL AGENCIES:
  12. REFERENCES:

SYNONYMS:

  1. Agricide maggot killer (F)
  2. Alltox
  3. Anatox
  4. Attac 4 - 2
  5. Attac 4 - 4
  6. Attac 6
  7. Attac 6 - 3
  8. Attac 8
  9. Camphechlor
  10. Camphochlor
  11. Camphoclor
  12. Camphofene huileux
  13. Chlorinated camphene
  14. Chlorinated camphene (OSHA)
  15. Chlorinated camphene 60% (ACGIH)
  16. Chlorinated camphene, technical
  17. Clor Chem T - 590
  18. Compound 3956
  19. Cristoxo 90
  20. ENT 9,735
  21. Estonox
  22. Fasco - terpene
  1. Geniphene
  2. Hercules 3956
  3. Kamfochlor
  4. Latka 3956 (Czech)
  5. M 5055
  6. Melipax
  7. NCI - C00259
  8. PCC
  9. Phenacide
  10. Phenatox
  11. Polychlorocamphene
  12. RCRA waste number P123
  13. Strobane T - 90
  14. Strobane - T
  15. Toxafeen (Dutch)
  16. Toxakil
  17. Toxaphen (German)
  18. Toxaphene (OSHA)
  19. Toxaphene fume
  20. Toxon 63
  21. Toxyphen
  22. Vertac toxaphene 90


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
skin
mammal (species unspecified) 		500 mg moderate JAMAAP 149,1135,1952


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
cytogenetic analysis multiple
other fish 		1,500 µg/kg/10 day- continuous BIZNAT 94,441,1975
mutation in microorganisms Salmonella typhimurium 100 µg/plate (+enzymatic activation step) ENMUDM 8(Suppl 7),1,1986
mutation in microorganisms Salmonella typhimurium 500 µg/plate (-enzymatic activation step) SCIEAS 205,591,1979
micronucleus test human liver 20 µmol/L/24 hour TOLED5 143,144,2003
morphological transform mouse embryo 12,400 µg/L PMRSDJ 5,659,1985
phage inhibition capacity Escherichia coli 100 µmol/L MUREAV 182,193,1987
phage inhibition capacity Escherichia coli 0.381 mmol/L (+enzymatic activation step) EMMUEG 36,206,2000
sister chromatid exchange hamster lung 5 mg/L MUREAV 230,29,1990
sister chromatid exchange human lymphocyte 10 µmol/L ARTODN 52,221,1983


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
hamster 		lowest published toxic dose: 64 mg/kg (16 day pregnant) Reproductive: Other developmental abnormalities VCVPS* -,304,1998
oral
hamster 		lowest published toxic dose: 280 mg/kg (10 week prior to copulation) Reproductive: Other developmental abnormalities VCVPS* -,304,1998
oral
mouse 		lowest published toxic dose: 375 mg/kg (8-12 day pregnant) Reproductive: Effects on newborn: Growth statistics (e.g., reduced weight gain) JTEHD6 10,541,1982
oral
mouse 		lowest published toxic dose: 100 mg/kg (8 day pregnant) Reproductive: Specific developmental abnormalities: Musculoskeletal system TCMUD8 5,3,1985
oral
mouse 		lowest published toxic dose: 375 mg/kg (8-12 day pregnant) Reproductive: Effects on newborn: Physical

Reproductive: Effects on newborn: Delayed effects 		TCMUD8 4,403,1984
oral
rat 		lowest published toxic dose: 280 mg/kg (10 week male) Reproductive: Paternal effects: Spermatogenesis (including genetic material, sperm morphology, motility, and count) GISAAA 45(5),14,1980
oral
rat 		lowest published toxic dose: 900 µg/kg (5-22 day pregnant) Reproductive: Effects on newborn: Behavioral AECTCV 9,247,1980
oral
rat 		lowest published toxic dose: 150 mg/kg (7-16 day pregnant) Reproductive: Specific developmental abnormalities: Musculoskeletal system BECTA6 15,660,1976
oral
rat 		lowest published toxic dose: 250 mg/kg (7-16 day pregnant) Reproductive: Effects on embryo or fetus: Fetotoxicity (except death, e.g., stunted fetus) BECTA6 15,660,1976
oral
rat 		lowest published toxic dose: 88 mg/kg (22 day pregnant) Reproductive: Other developmental abnormalities VCVPS* -,304,1998
oral
rat 		lowest published toxic dose: 280 mg/kg (10 week prior to copulation) Reproductive: Other developmental abnormalities VCVPS* -,304,1998


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
mouse 		lowest published toxic dose: 6,600 mg/kg/80 week- continuous Tumorigenic: Carcinogenic by RTECS criteria

Liver: Tumors 		NCITR* NCI-TR-37,1979
oral
mouse 		toxic dose : 13 gm/kg/80 week- continuous Tumorigenic: Carcinogenic by RTECS criteria

Liver: Tumors 		NCITR* NCI-TR-37,1979
oral
rat 		lowest published toxic dose: 30 gm/kg/80 week- continuous Tumorigenic: Equivocal tumorigenic agent by RTECS criteria

Blood: Lymphoma including Hodgkin's disease 		NCITR* NCI-TR-37,1979


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
mouse 		lowest published lethal concentration: 2,000 mg/m3/2 hour N/R JAMAAP 149,1135,1952
inhalation
mouse 		lethal concentration (50 percent kill): 2,000 mg/m3/2 hour Behavioral: Tetany

Lung, Thorax, or Respiration: Respiratory obstruction

Nutritional and Gross Metabolic: Body temperature decrease 		VCVPS* -,302,1998
intraperitoneal
mouse 		lethal dose (50 percent kill): 42 mg/kg N/R JAFCAU 22,653,1974
intraperitoneal
rat 		lowest published lethal dose: 70 mg/kg Eye: Lacrimation

Lung, Thorax, or Respiration: Dyspnea

Gastrointestinal: Hypermotility, diarrhea 		BECTA6 19,47,1978
intraperitoneal
rat 		lowest published toxic dose: 165.5 mg/kg Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.)

Biochemical: Metabolism (intermediary): Other 		GEPHDP 18,165,1987
oral
cat 		lowest published toxic dose: 70 mg/kg Behavioral: Tetany

Behavioral: Muscle contraction or spasticity 		VCVPS* -,302,1998
oral
duck 		lethal dose (50 percent kill): 31 mg/kg N/R DOEAAH 35,25,1979
oral
dog 		lethal dose (50 percent kill): 15 mg/kg Behavioral: Tetany

Behavioral: Muscle contraction or spasticity 		VCVPS* -,302,1998
oral
dog 		lethal dose (50 percent kill): 15 mg/kg N/R VCVGH* -,556,1990
oral
guinea pig 		lethal dose (50 percent kill): 250 mg/kg Behavioral: Tetany

Lung, Thorax, or Respiration: Respiratory obstruction

Nutritional and Gross Metabolic: Body temperature decrease 		VCVPS* -,302,1998
oral
guinea pig 		lethal dose (50 percent kill): 250 mg/kg N/R VCVGH* -,556,1990
oral
hamster 		lethal dose (50 percent kill): 200 mg/kg N/R TXAPA9 48,A192,1979
oral
human 		lowest published lethal dose: 28 mg/kg Behavioral: Somnolence (general depressed activity)

Behavioral: Convulsions or effect on seizure threshold

Behavioral: Coma 		34ZIAG -,598,1969
oral
human 		lowest published lethal dose: 60 mg/kg Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Multiple enzyme effects VCVPS* -,303,1998
oral
man 		lowest published lethal dose: 29 mg/kg Behavioral: Convulsions or effect on seizure threshold

Lung, Thorax, or Respiration: Cyanosis

Lung, Thorax, or Respiration: Other changes 		CMEP** -,-,1956
oral
mouse 		lethal dose (50 percent kill): 45 mg/kg Behavioral: Tetany

Lung, Thorax, or Respiration: Respiratory obstruction

Nutritional and Gross Metabolic: Body temperature decrease 		VCVPS* -,302,1998
oral
mouse 		lethal dose (50 percent kill): 45 mg/kg N/R VCVGH* -,556,1990
oral
rat 		lethal dose (50 percent kill): 40 mg/kg Behavioral: Tetany

Lung, Thorax, or Respiration: Respiratory obstruction

Nutritional and Gross Metabolic: Body temperature decrease 		VCVPS* -,302,1998
oral
rat 		lowest published toxic dose: 300 mg/kg N/R VCVPS* -,302,1998
oral
rat 		lethal dose (50 percent kill): 40 mg/kg N/R VCVGH* -,556,1990
oral
rat 		lowest published toxic dose: 300 mg/kg Behavioral: Tetany

Behavioral: Muscle contraction or spasticity 		VCVPS* -,302,1998
oral
rabbit 		lethal dose (50 percent kill): 25 mg/kg Behavioral: Tetany

Lung, Thorax, or Respiration: Respiratory obstruction

Nutritional and Gross Metabolic: Body temperature decrease 		VCVPS* -,302,1998
oral
rabbit 		lethal dose (50 percent kill): 25 mg/kg N/R VCVGH* -,556,1990
parenteral
rat 		lethal dose (50 percent kill): 90 mg/kg N/R DEVEAA 26,5,1972
skin
human 		lowest published toxic dose: 657 mg/kg Skin: After systemic exposure: Dermatitis, allergic CMEP** -,1,1956
skin
mouse 		lethal dose (50 percent kill): 250 mg/kg N/R VCVGH* -,556,1990
skin
rat 		lethal dose (50 percent kill): 940 mg/kg Behavioral: Alteration of classical conditioning

Behavioral: Tremor

Lung, Thorax, or Respiration: Dyspnea 		VCVPS* -,303,1998
skin
rat 		lethal dose (50 percent kill): 250 mg/kg N/R VCVGH* -,556,1990
skin
rabbit 		lethal dose (50 percent kill): 1,025 mg/kg Behavioral: Excitement

Behavioral: Food intake (animal)

Vascular: Regional or general arteriolar or venous dilation 		JEENAI 46,702,1953
skin
rabbit 		lethal dose (50 percent kill): 250 mg/kg N/R VCVGH* -,556,1990
unreported route
man 		lowest published lethal dose: 44 mg/kg N/R 85DCAI 2,73,1970
unreported route
mouse 		lethal dose (50 percent kill): 45 mg/kg N/R CYGEDX 8(1),23,1974
unreported route
rat 		lethal dose (50 percent kill): 240 mg/kg N/R CYGEDX 8(1),23,1974


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
human 		lowest published toxic concentration: 20 mg/m3/3 year- intermittent Cardiac: Arrythmias (indlucing changes in conduction)

Behavioral: Wakefulness

Behavioral: Headache 		VCVPS* -,304,1998
intraperitoneal
rat 		lowest published toxic dose: 175 mg/kg/7 day- intermittent Liver: Other changes

Biochemical: Metabolism (intermediary): Other 		TXAPA9 19,234,1971
oral
dog 		lowest published toxic dose: 385 mg/kg/13 week- intermittent Liver: Changes in liver weight

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Phosphatases 		FAATDF 7,406,1986
oral
guinea pig 		lowest published toxic dose: 120 mg/kg/60 day- intermittent Liver: Changes in liver weight

Kidney, Ureter, and Bladder: Changes in both tubules and glomeruli

Nutritional and Gross Metabolic: Weight loss or decreased weight gain 		JEBIDP 13,315,1992
oral
hamster 		lowest published toxic dose: 64 mg/kg/16 day- intermittent Reproductive: Maternal effects: Ovaries, fallopian tubes VCVPS* -,304,1998
oral
hamster 		lowest published toxic dose: 280 mg/kg/10 week- intermittent Reproductive: Maternal effects: Ovaries, fallopian tubes VCVPS* -,304,1998
oral
monkey 		lowest published toxic dose: 95 mg/kg/34 week- intermittent Immunological Including Allergic: Decrease in cellular immune response TOXID9 54,335,2000
oral
monkey 		lowest published toxic dose: 6.3 mg/kg/9 week- continuous Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol) FCTOD7 39,467,2001
oral
monkey 		lowest published toxic dose: 392 mg/kg/70 week- continuous Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Skin: After systemic exposure: Dermatitis, other

Skin and Appendages: Other: Nails 		FCTOD7 39,467,2001
oral
monkey 		lowest published toxic dose: 148 mg/kg/53 week- intermittent Immunological Including Allergic: Decrease in humoral immune response FCTOD7 39,947,2001
oral
monkey 		lowest published toxic dose: 296 mg/kg/46 week- intermittent Immunological Including Allergic: Decrease in cellular immune response

Immunological Including Allergic: Decrease in humoral immune response 		FCTOD7 39,947,2001
oral
monkey 		lowest published toxic dose: 268 mg/kg/34 week- continuous Immunological Including Allergic: Decrease in humoral immune response FCTOD7 39,1243,2001
oral
monkey 		lowest published toxic dose: 364 mg/kg/52 week- continuous Endocrine: Changes in spleen weight

Endocrine: Changes in thymus weight 		FCTOD7 39,1243,2001
oral
monkey 		lowest published toxic dose: 364 mg/kg/52 week- continuous Liver: Changes in liver weight

Endocrine: Effect on menstrual cycle

Endocrine: Changes in spleen weight 		FCTOD7 39,1243,2001
oral
quail 		lowest published toxic dose: 126 mg/kg/18 week- continuous Endocrine: Changes in adrenal weight

Endocrine: Changes in thyroid weight

Nutritional and Gross Metabolic: Weight loss or decreased weight gain 		POSCAL 53,125,1974
oral
rat 		lowest published toxic dose: 4,186 mg/kg/13 week- continuous Liver: Changes in liver weight

Kidney, Ureter, and Bladder: Changes in bladder weight

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) 		FAATDF 7,406,1986
oral
rat 		lowest published toxic dose: 328 mg/kg/39 week- continuous Liver: Other changes AMPLAO 64,614,1957
oral
rat 		lowest published toxic dose: 1,875 mg/kg/25 day- intermittent Endocrine: Other changes RTOPDW 24,184,1996
oral
rat 		lowest published toxic dose: 120 mg/kg/4 week- intermittent Behavioral: Somnolence (general depressed activity)

Behavioral: Food intake (animal)

Immunological Including Allergic: Decrease in cellular immune response 		VCVPS* -,304,1998
oral
rat 		lowest published toxic dose: 88 mg/kg/22 day- intermittent Reproductive: Maternal effects: Ovaries, fallopian tubes VCVPS* -,304,1998
oral
rat 		lowest published toxic dose: 280 mg/kg/10 week- intermittent Reproductive: Maternal effects: Ovaries, fallopian tubes VCVPS* -,304,1998
oral
rabbit 		lowest published toxic dose: 456.2 mg/kg/26 week- intermittent Musculoskeletal: Other changes VCVPS* -,304,1998
unreported route
chicken 		lowest published toxic dose: 480 mg/kg/10 day- intermittent Brain and Coverings: Changes in surface EEG

Peripheral Nerve and Sensation: Spastic paralysis with/without sensory change

Behavioral: Somnolence (general depressed activity) 		FIZHDO 27,557,1981
unreported route
mammal (species unspecified) 		lowest published toxic dose: 73 gm/kg/2 year- intermittent Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field VCVPS* -,304,1998


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 0.5 mg/m3 (skin) DTLVS* TLV/BEI,2002
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 0.5 mg/m3 (skin);short term exposure limit 1 mg/m3 (skin) DTLVS* TLV/BEI,2003
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value Confirmed Animal Carcinogen with Unknown DTLVS* TLV/BEI,2003
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value short term exposure limit 1 mg/m3 (skin) DTLVS* TLV/BEI,2002
International Agency for Research on Cancer (IARC) Cancer Review Animal Sufficient Evidence IMEMDT 79,-,2000
International Agency for Research on Cancer (IARC) Cancer Review Human Inadequate Evidence IMEMDT 79,-,2000
International Agency for Research on Cancer (IARC) Cancer Review Group 2B IMEMDT 79,-,2000
TOXICOLOGY REVIEW
ANAEA3 35,165,1975
TOXICOLOGY REVIEW
DTTIAF 80,485,1973
TOXICOLOGY REVIEW
RREVAH 56,107,1975
TOXICOLOGY REVIEW
MUREAV 567,227,2004


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES: Cancelled RBREV* -,214,1998
Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 0.5 mg/m3 (skin) DTLVS* 3,45,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 0.5 mg/m3 (skin) CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 0.5 mg/m3 (skin) CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 0.5 mg/m3 (skin) CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 0.5 mg/m3 (skin) CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - ARAB Republic of Egypt time-weighted average 0.5 mg/m3, Skin, JAN1993
Occupational Exposure Limit - AUSTRALIA time-weighted average 0.5 mg/m3, short term exposure limit 1 mg/m3, Skin, JAN1993
Occupational Exposure Limit - AUSTRIA MAK 0.5 mg/m3, Skin, JAN1999
Occupational Exposure Limit - BELGIUM time-weighted average 0.5 mg/m3, short term exposure limit 1 mg/m3, Skin, JAN1993
Occupational Exposure Limit - DENMARK time-weighted average 0.5 mg/m3, Skin, JAN1999
Occupational Exposure Limit - FINLAND time-weighted average 0.5 mg/m3, short term exposure limit 1.5 mg/m3, Skin, JAN1999
Occupational Exposure Limit - FRANCE VME 0.5 mg/m3, Skin, continuous3 Carcinogen, JAN1999
Occupational Exposure Limit - GERMANY MAK 0.5 mg/m3 (total dust), Skin, JAN1999
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 0.5 mg/m3, Skin, 2003
Occupational Exposure Limit - NORWAY time-weighted average 0.5 mg/m3, JAN1999
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 0.5 mg/m3, Skin, JAN1993
Occupational Exposure Limit - SWITZERLAND MAK- week 0.5 mg/m3, Skin, JAN1999
Occupational Exposure Limit - THAILAND time-weighted average 0.5 mg/m3, JAN1993
Occupational Exposure Limit - TURKEY time-weighted average 0.5 mg/m3, Skin, JAN1993
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

short term exposure limit 1 mg/m3 (skin)
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
short term exposure limit 1 mg/m3 (skin)


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO CHLORINATED CAMPHENE-air Carcinogen lowest feasible conc. NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 73500;
Number of Industries 1;
Total Number of Facilities 68;
Number of Occupations 2;
Total Number of Employees Exposed 203


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
ATSDR TOXICOLOGY PROFILE (NTIS** PB/97/121057/AS)
EPA GENETOX PROGRAM 1988, Positive: Carcinogenicity-mouse/rat
Used as an insecticide for the control of grasshoppers, army-worms and all major cotton pests
EPA TSCA Section 8(d) unpublished health/safety studies
On EPA IRIS database
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NIOSH Analytical Method, 1994: Chlorinated camphene, 5039
NCI Carcinogenesis Bioassay (feed);clear evidence:mouse NCITR* NCI-TR-37,1979
NCI Carcinogenesis Bioassay (feed);equivocal evidence:rat NCITR* NCI-TR-37,1979
NTP 11th Report on Carcinogens,2004:Reasonably anticipated to be a human carcinogen


REFERENCES:

CODEN
REFERENCE
34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969
85DCAI "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970
AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973-
AMPLAO AMA Archives of Pathology. (Chicago, IL) V.50(4)-69, 1950-60. For publisher information, see APLMAS.
ANAEA3 Annals of Allergy. (American College of Allergists, POB 20671, Bloomington, MN 55420) V.1- 1943-
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974-
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CMEP** "Clinical Memoranda on Economic Poisons," U.S. Dept. HEW, Public Health Service, Communicable Disease Center, Atlanta, GA, 1956
CYGEDX Cytology and Genetics (English Translation). Translation of TGANAK. (Allerton Press Inc., 150 Fifth Ave., New York, NY 10011) V.8- 1974-
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DOEAAH Down to Earth. (Dow Chemical USA, Agricultural Products Dept., Midland, MI 48640) V.1- 1945-
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
DTTIAF Deutsche Tieraerztliche Wochenschrift. (Hanover, Fed. Rep. Ger.) V.1-77, 1893-1970.
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987-
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG.
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1-40, 1981-97. For publisher information, see TOSCF2
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982-
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GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972-
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JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76-
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-
NCITR* National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD) No.0-205. For publisher information, see NTPTR*.
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
PMRSDJ Progress in Mutation Research. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1981-
POSCAL Poultry Science. (Poultry Science Assoc., Inc., 309 W. Clark St., Champaign, IL 61820) V.1- 1921-
RBREV* Status of Pesticides in Registration, Reregistration, and Special Review (Rainbow Report), Special Review and Reregistration Division Office of Pesticide Programs U.S. Environmental Protection Agency, 401 M. Street, S.W., Washington, D.C. 20460, Spring 1998
RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962-
RTOPDW Regulatory Toxicology and Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981-
SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895-
TCMUD8 Teratogenesis, Carcinogenesis, and Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1980-
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TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981-
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VCVGH* "Vrednie chemichescie veshestva, galogenproisvodnie uglevodorodov". (Hazardous substances: Galogenated hydrocarbons) Bandman A.L. et al., Chimia, 1990.
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Used as an insecticide for the control of grasshoppers, army-worms and all major cotton pests

RTECS Compound Description:
   Agricultural Chemical
   Tumorigen
   Mutagen
   Reproductive Effector
   Human Data
   Natural Product
   Primary Irritant

ALT CAS #: 8022-04-6
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