The Registry of Toxic Effects of Chemical Substances

Toluene - 2,5 - diamine, sulfate (1:1)

RTECS #: XT0525000

CAS #: 615-50-9

UPDATE: October 1997 MW: 220.27 MF: C7H10N2•H2O4S


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. MUTATION DATA:
  3. ACUTE TOXICITY DATA:
  4. NIOSH DOCUMENTATION AND SURVEILLANCE:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. 1,4 - Benzenediamine, 2 - methyl - , sulfate (1:1) (9CI)
  2. C.I. 76043
  3. p - Diaminotoluene sulfate
  4. 2,5 - Diaminotoluene sulfate
  5. 2,5 - Diaminotoluene sulphate
  6. 2 - Methyl - 1,4 - benzenediamine sulfate (1:1)
  1. 2 - Methyl - p - phenylenediamine sulphate
  2. Toluene - 2,5 - diamine sulphate
  3. Toluylene - 2,5 - diamine sulphate
  4. p - Tolylenediamine sulphate
  5. p - Toluenediamine sulphate
  6. p - Toluylenediamine sulphate


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
mutation in microorganisms Salmonella typhimurium 250 µg/plate (-enzymatic activation step) JJIND8 71,293,1983


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intraperitoneal
rat 		lethal dose (50 percent kill): 49 mg/kg N/R JTEHD6 2,657,1977
oral
rat 		lethal dose (50 percent kill): 98 mg/kg N/R JTEHD6 2,657,1977


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X2324;
Number of Industries 1;
Total Number of Facilities 2,288;
Number of Occupations 1;
Total Number of Employees Exposed 21,487;
Total Number of Female Employees Exposed 16,214


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used to dye furs, and in hair dye formulations
EPA TSCA 8(a) PRELIMINARY ASSESSMENT INFORMATION, PROPOSED RULE FEREAC 47,27009,82
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ.
JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76-

Used to dye furs, and in hair dye formulations

RTECS Compound Description:
   Mutagen

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