The Registry of Toxic Effects of Chemical Substances

Tin (IV) chloride (1:4)

RTECS #: XP8750000

CAS #: 7646-78-8

UPDATE: May 2004 MW: 260.49 MF: Cl4Sn


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. MUTATION DATA:
  4. ACUTE TOXICITY DATA:
  5. OTHER MULTIPLE DOSE DATA:
  6. REVIEWS:
  7. STANDARDS AND REGULATIONS:
  8. NIOSH DOCUMENTATION AND SURVEILLANCE:
  9. STATUS IN FEDERAL AGENCIES:
  10. REFERENCES:

SYNONYMS:

  1. Etain (tetrachlorure d') (French)
  2. Libavius fuming spirit
  3. Stagno (tetracloruro di) (Italian)
  4. Stannane, tetrachloro -
  5. Stannic chloride
  1. Tin chloride
  2. Tin perchloride
  3. Tin tetrachloride
  4. Tintetrachloride (Dutch)
  5. Zinntetrachlorid (German)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
skin
human 		5%/48 hour CODEDG 29,110,1993


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
cytogenetic analysis human leukocyte 4 mg/L CYTBAI 56,23,1988


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
rat 		lethal concentration (50 percent kill): 2,300 mg/m3/10 minute N/R TOXID9 1,77,1981
intraperitoneal
mouse 		lethal dose (50 percent kill): 99 mg/kg N/R TXAPA9 63,461,1982


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
rat 		lowest published toxic dose: 166 mg/kg/4 week- intermittent Autonomic Nervous System: Sympathomimetic PJPPAA 41,7,1989


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 2 mg(Sn)/m3 DTLVS* TLV/BEI,1999


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 2 mg(Sn)/m3 DTLVS* 3,257,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 2 mg(Sn)/m3 CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 2 mg(Sn)/m3 CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 2 mg(Sn)/m3 CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 2 mg(Sn)/m3 CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - AUSTRALIA time-weighted average 2 mg(Sn)/m3, JAN1993
Occupational Exposure Limit - AUSTRIA MAK 2 mg/m3, JAN1999
Occupational Exposure Limit - BELGIUM time-weighted average 2 mg(Sn)/m3, JAN1993
Occupational Exposure Limit - DENMARK time-weighted average 2 mg(Sn)/m3, JAN1999
Occupational Exposure Limit - FINLAND time-weighted average 2 mg(Sn)/m3, JAN1999
Occupational Exposure Limit - GERMANY MAK 2 mg(Sn)/m3, JAN1999
Occupational Exposure Limit - HUNGARY time-weighted average 1 mg(Sn)/m3, short term exposure limit 2 mg(Sn)/m3, Skin, JAN1993
Occupational Exposure Limit - NORWAY time-weighted average 2 mg(Sn)/m3, JAN1999
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 2 mg(Sn)/m3, JAN1993
Occupational Exposure Limit - POLAND time-weighted average 2 mg(Sn)/m3, JAN1999
Occupational Exposure Limit - SWITZERLAND MAK- week 2 mg(Sn)/m3, KZG- week 4 mg(Sn)/m3, JAN1999
Occupational Exposure Limit - THAILAND time-weighted average 2 mg(Sn)/m3, JAN1993
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 2 mg(Sn)/m3, short term exposure limit 4 mg(Sn)/m3, SEP2000
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

time-weighted average 2 mg(Sn)/m3
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
time-weighted average 2 mg(Sn)/m3


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 80077;
Number of Industries 11;
Total Number of Facilities 408;
Number of Occupations 18;
Total Number of Employees Exposed 2,399
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 80077;
Number of Industries 5;
Total Number of Facilities 201;
Number of Occupations 16;
Total Number of Employees Exposed 7,310;
Total Number of Female Employees Exposed 4,836


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA GENETOX PROGRAM 1988, Negative: B subtilis rec assay
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
CODEDG Contact Dermatitis. Environmental and Occupational Dermatitis. (Munksgaard International Pub., c/o Publications Expediting Inc., 200 Meacham Ave., Elmont, NY 11003) V.1- 1975-
CYTBAI Cytobios. (Faculty Press, 88 Regent St., Cambridge, UK) V.1- 1969-
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
PJPPAA Polish Journal of Pharmacology and Pharmacy. (ARS Polona, POB 1001, 00-068 Warsaw 1, Poland) V.25-44, 1973-92. For publisher information, see PJPAE3
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981-
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-

RTECS Compound Description:
   Mutagen
   Hormone

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