The Registry of Toxic Effects of Chemical Substances

Sulfur trioxide

RTECS #: WT4830000

CAS #: 7446-11-9

UPDATE: May 2005 MW: 80.06 MF: O3S


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. REVIEWS:
  4. STANDARDS AND REGULATIONS:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. Sulfan
  2. Sulfuric oxide
  1. Sulfuric anhydride
  2. Sulphur trioxide


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
guinea pig 		lowest published lethal concentration: 30 mg/m3/6 hour Liver: Hepatitis (hepatocellular necrosis), diffuse

Lung, Thorax, or Respiration: Structural or functional change in trachea or bronchi

Endocrine: Other changes 		JPBAA7 68,197,1954
inhalation
human 		lowest published toxic concentration: 30 mg/m3 Olfaction: Other olfaction effects

Lung, Thorax, or Respiration: Cough

Lung, Thorax, or Respiration: Other changes 		JPBAA7 68,197,1954


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
International Agency for Research on Cancer (IARC) Cancer Review Human Sufficient Evidence IMEMDT 54,41,1992
International Agency for Research on Cancer (IARC) Cancer Review Group 1 IMEMDT 54,41,1992
TOXICOLOGY REVIEW
AEHLAU 16,903,1968


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Occupational Exposure Limit - FINLAND short term exposure limit 1 ppm (3 mg/m3), Skin, JAN1999
Occupational Exposure Limit - HUNGARY short term exposure limit 1 mg/m3, JAN1993
Occupational Exposure Limit - POLAND MAC(time-weighted average) 1 mg/m3, MAC(short term exposure limit) 3 mg/m3, JAN1999
Occupational Exposure Limit - RUSSIA short term exposure limit 1 mg/m3, Skin, JAN1993


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: M0745;
Number of Industries 20;
Total Number of Facilities 1,316;
Number of Occupations 39;
Total Number of Employees Exposed 51,404
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: M0745;
Number of Industries 17;
Total Number of Facilities 2,524;
Number of Occupations 27;
Total Number of Employees Exposed 56,102;
Total Number of Female Employees Exposed 3,077


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
ATSDR TOXICOLOGY PROFILE (NTIS** PB/99/122038)
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as sulfating and sulfonating agent for detergent, lubricating oil additives
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
NTP 11th Report on Carcinogens,2004:Known to be human carcinogen


REFERENCES:

CODEN
REFERENCE
AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960-
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972-
JPBAA7 Journal of Pathology and Bacteriology. (London, UK) V.1-96, 1892-1968. For publisher information, see JPTLAS.

Used as sulfating and sulfonating agent for detergent, lubricating oil additives

NIOSH PROFILE (DIESEL EMISSIONS), SRI, 2/77

NIOSH PROFILE (INCINERATION), FIRL, 4/78

RTECS Compound Description:
   Tumorigen
   Human Data

 Click Here for Additional Information about RTECS