The Registry of Toxic Effects of Chemical Substances

Sulfamic acid

RTECS #: WO5950000

CAS #: 5329-14-6


UPDATE: August 2003 MW: 97.10 MF: H3NO3S


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. ACUTE TOXICITY DATA:
  4. STANDARDS AND REGULATIONS:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. Amidosulfonic acid
  2. Amidosulfuric acid
  3. Aminosulfonic acid
  4. Kyselina amidosulfonova (Czech)
  1. Kyselina sulfaminova (Czech)
  2. Sulfamidic acid
  3. Sulphamic acid


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
eye
rabbit
20 mg moderate JIHTAB 25,26,1943
eye
rabbit
250 µg/24 hour severe 28ZPAK -,18,1972
skin
human
4%/5 day- intermittent mild JIHTAB 25,26,1943
skin
rabbit
500 mg/24 hour severe 28ZPAK -,18,1972


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
intraperitoneal
rat
lowest published lethal dose: 100 mg/kg N/R JIHTAB 25,26,1943
oral
guinea pig
lethal dose (50 percent kill): 1,050 mg/kg Behavioral: Altered sleep time (including change in righting reflex)

Behavioral: Excitement

Behavioral: Rigidity (includes catalepsy)
GISAAA 52(10),88,1987
oral
mouse
lethal dose (50 percent kill): 1,312 mg/kg Behavioral: Altered sleep time (including change in righting reflex)

Behavioral: Excitement

Behavioral: Rigidity (includes catalepsy)
GISAAA 52(10),88,1987
oral
rat
lethal dose (50 percent kill): 3,160 mg/kg N/R 28ZPAK -,18,1972


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC 54,7740,1989
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES: Unsupported RBREV* -,337,1998


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 82834;
Number of Industries 78;
Total Number of Facilities 5,516;
Number of Occupations 54;
Total Number of Employees Exposed 56,781
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 82834;
Number of Industries 89;
Total Number of Facilities 6,660;
Number of Occupations 74;
Total Number of Employees Exposed 133,549;
Total Number of Female Employees Exposed 30,034


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used in metal and ceramic cleaning, bleaching paper pulp and textiles
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE

28ZPAK "Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku," Marhold, J.V., Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha, Czechoslovakia, 1972
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-
JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU.
RBREV* Status of Pesticides in Registration, Reregistration, and Special Review (Rainbow Report), Special Review and Reregistration Division Office of Pesticide Programs U.S. Environmental Protection Agency, 401 M. Street, S.W., Washington, D.C. 20460, Spring 1998

Used in metal and ceramic cleaning, bleaching paper pulp and textiles

RTECS Compound Description:
   Agricultural Chemical
   Primary Irritant

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