The Registry of Toxic Effects of Chemical Substances
Styrene polymer |
UPDATE: May 2004 | MW: N/R | MF: (C8H8)x |
SYNONYMS:
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SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
|
N/R |
N/R
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N/R
|
N/R
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MUTATION DATA AND REFERENCES:
SYSTEM TEST
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ROUTE/ | ORGANISM/ TISSUE
DOSE
|
REFERENCE
|
N/R
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N/R
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N/R
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N/R
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REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
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N/R |
N/R
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N/R
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N/R
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TUMORIGENIC DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
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implant | rat
lowest published toxic dose: 19 mg/kg
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Tumorigenic: Equivocal tumorigenic agent by RTECS criteria | Tumorigenic: Tumors at site of application
CNREA8 15,333,1955
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ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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intratracheal | mouse
lowest published toxic dose: 20 mg/kg
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Lung, Thorax, or Respiration: Other changes | Biochemical: Metabolism (intermediary): Effect on inflammation or mediation of inflammation
TOXID9 72,288,2003
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OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
intravenous | rat
lowest published toxic dose: 200 mg/kg/2 week- intermittent
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Liver: Liver function tests impaired | Biochemical: Metabolism (intermediary): Other proteins
TXAPA9 130,272,1995
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REVIEWS:
ORGANIZATION
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STANDARD
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REFERENCE
International Agency for Research on Cancer (IARC) Cancer Review
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Human No Adequate Data
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IMEMDT 19,231,1979
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International Agency for Research on Cancer (IARC) Cancer Review
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Animal Inadequate Evidence
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IMEMDT 19,231,1979
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International Agency for Research on Cancer (IARC) Cancer Review
|
Group 3
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IMSUDL 7,56,1987
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TOXICOLOGY REVIEW
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STRAAA 100,192,1956
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STANDARDS AND REGULATIONS:
ORGANIZATION
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STANDARD
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REFERENCE
N/R
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N/R
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N/R
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NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION
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STANDARD or SURVEY
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REFERENCE
National Occupational Hazard Survey 1974
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National Occupational Hazard Survey 1974: Hazard Code: M3416; | Number of Industries 15; Total Number of Facilities 1,604; Number of Occupations 25; Total Number of Employees Exposed 6,915
National Occupational Hazard Survey 1974
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National Occupational Hazard Survey 1974: Hazard Code: M3828; | Number of Industries 120; Total Number of Facilities 10,731; Number of Occupations 101; Total Number of Employees Exposed 147,128
National Occupational Exposure Survey 1983
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National Occupational Exposure Survey 1983: Hazard Code: X6970; |
Number of Industries 101; Total Number of Facilities 11,403; Number of Occupations 131; Total Number of Employees Exposed 400,575; Total Number of Female Employees Exposed 182,417 |
STATUS IN FEDERAL AGENCIES:
ORGANIZATION
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REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
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Used in packaging and manufacture of housewares, furnishings, toys, sporting goods
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EPA TSCA Section 8(d) unpublished health/safety studies
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EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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REFERENCES:
CODEN
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REFERENCE
CNREA8
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Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA
19106) V.1- 1941-
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IMEMDT
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IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications
Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972-
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IMSUDL
|
IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY
12210) No.1- 1979-
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STRAAA
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Strahlentherapie. (Urban & Schwarzenberg, Postfach 202440, D-8000 Munich 2, Fed. Rep. Ger.)
V.1- 1912-
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TOXID9
|
Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1-
1981-
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TXAPA9
|
Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)
V.1- 1959-
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