The Registry of Toxic Effects of Chemical Substances

Styrene, o - chloro -

RTECS #: WL4160000

CAS #: 2039-87-4

UPDATE: November 2004 MW: 138.60 MF: C8H7Cl


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. REVIEWS:
  4. STANDARDS AND REGULATIONS:
  5. NIOSH DOCUMENTATION AND SURVEILLANCE:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. Chlorostyrene
  2. o - Chlorostyrene
  1. 2 - Chlorostyrene
  2. o - Chlorostyrene (ACGIH)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
rat 		lethal dose (50 percent kill): 3,810 µL/kg Behavioral: Muscle weakness

Lung, Thorax, or Respiration: Dyspnea

Gastrointestinal: Hypermotility, diarrhea 		NTIS** OTS0555044
oral
rabbit 		lethal dose (50 percent kill): 4,230 µL/kg Behavioral: Muscle weakness

Lung, Thorax, or Respiration: Dyspnea

Kidney, Ureter, and Bladder: Other changes in urine composition 		NTIS** OTS0555044


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 50 ppm DTLVS* TLV/BEI,2002
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 50 ppm;short term exposure limit 75 ppm DTLVS* TLV/BEI,2003
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value short term exposure limit 75 ppm DTLVS* TLV/BEI,2002


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Occupational Exposure Limit - AUSTRALIA time-weighted average 50 ppm (285 mg/m3), short term exposure limit 75 ppm (430 mg/m3), JAN1993
Occupational Exposure Limit - AUSTRIA MAK 50 ppm (285 mg/m3), JAN1999
Occupational Exposure Limit - BELGIUM time-weighted average 50 ppm, short term exposure limit 75 ppm, JAN1993
Occupational Exposure Limit - FRANCE VME 50 ppm (285 mg/m3), JAN1999
Occupational Exposure Limit - NORWAY time-weighted average 25 ppm (140 mg/m3), JAN1999
Occupational Exposure Limit - SWITZERLAND MAK- week 50 ppm (215 mg/m3), KZG- week 100 ppm (430 mg/m3),JAN1999
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 285 mg/m3, 2003
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

short term exposure limit 75 ppm
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
short term exposure limit 75 ppm


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO o-CHLOROSTYRENE-air 10 hour time-weighted average 50 ppm;
short term exposure limit 75 ppm 		NIOSH* DHHS #95-121,1995


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information.

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