The Registry of Toxic Effects of Chemical Substances
Sodium iodide RTECS #: WB6475000
CAS #: 7681-82-5
The Registry of Toxic Effects of Chemical Substances
Sodium iodide |
| UPDATE: May 2004 | MW: 149.89 | MF: INa |
SYNONYMS:
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SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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eye | rabbit
100 mg/24 hour
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moderate
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28ZPAK -,21,1972
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skin | rabbit
500 mg/24 hour
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moderate
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28ZPAK -,21,1972
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MUTATION DATA AND REFERENCES:
SYSTEM TEST
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ROUTE/ | ORGANISM/ TISSUE
DOSE
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REFERENCE
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N/R
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N/R
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N/R
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N/R
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REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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oral | woman
lowest published toxic dose: 9,240 mg/kg (1-43 week pregnant)
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Reproductive: Specific developmental abnormalities: Endocrine system | Reproductive: Effects on newborn: Other postnatal measures or effects
ADCHAK 38,526,1963
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TUMORIGENIC DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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N/R |
N/R
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N/R
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N/R
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ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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inhalation | mouse
lowest published lethal concentration: 50,000 mg/m3/2 hour
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N/R
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VCVN5* -,404,1989
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intraperitoneal | mouse
lethal dose (50 percent kill): 430 mg/kg
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N/R
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PSEBAA 115,551,1964
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intraperitoneal | rat
lowest published toxic dose: 600 µg( intermittent)/kg
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Endocrine: Evidence of thyroid hypofunction
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FATOAO 45,96,1982
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intravenous | dog
lowest published lethal dose: 760 mg/kg
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N/R
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HBAMAK 4,1289,1935
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intravenous | rat
lethal dose (50 percent kill): 1,060 mg/kg
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N/R
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AEPPAE 222,584,1954
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oral | man
lowest published toxic dose: 100 µL/kg/14 day- intermittent
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Endocrine: Other changes | Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)
CLECAP 28,283,1988
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oral | mouse
lethal dose (50 percent kill): 1,000 mg/kg
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N/R
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VCVN5* -,404,1989
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oral | rat
lethal dose (50 percent kill): 4,340 mg/kg
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N/R
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28ZPAK -,21,1972
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oral | rat
lowest published lethal dose: 1,600 mg/kg
|
N/R
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VCVN5* -,404,1989
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oral | rabbit
lowest published lethal dose: 2,362 mg/kg
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N/R
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JPETAB 30,407,1927
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OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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oral | rat
lowest published toxic dose: 64,267 µg/kg/14 week- continuous
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Endocrine: Changes in thyroid weight | Blood: Other changes
JTEHD6 32,89,1991
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oral | rat
lowest published toxic dose: 84 gm/kg/28 day- continuous
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Skin and Appendages: Other glands | Nutritional and Gross Metabolic: Weight loss or decreased weight gain
PSEBAA 114,341,1963
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oral | rat
lowest published toxic dose: 7,497 mg/kg/90 day- continuous
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Endocrine: Changes in thyroid weight | Nutritional and Gross Metabolic: Weight loss or decreased weight gain Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
ACEDAB 69,321,1972
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oral | rat
lowest published toxic dose: 6,715.5 mg/kg/121 day- continuous
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Endocrine: Changes in thyroid weight | Nutritional and Gross Metabolic: Weight loss or decreased weight gain Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
ACEDAB 69,321,1972
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oral | rat
lowest published toxic dose: 840 mg/kg/12 week- continuous
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Endocrine: Other changes
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EJEND* 137,89,1997
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oral | rat
lowest published toxic dose: 140 mg/kg/2 week- intermittent
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Liver: Changes in liver weight
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TOXID9 72,284,2003
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REVIEWS:
ORGANIZATION
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STANDARD
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REFERENCE
N/R
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N/R
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N/R
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STANDARDS AND REGULATIONS:
ORGANIZATION
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STANDARD
|
|
REFERENCE
N/R
|
N/R
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N/R
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NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION
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STANDARD or SURVEY
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REFERENCE
National Occupational Hazard Survey 1974
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National Occupational Hazard Survey 1974: Hazard Code: 69120; | Number of Industries 7; Total Number of Facilities 529; Number of Occupations 9; Total Number of Employees Exposed 6,918
National Occupational Exposure Survey 1983
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National Occupational Exposure Survey 1983: Hazard Code: 69120 |
 ;Number of Industries 14; Total Number of Facilities 1,773; Number of Occupations 27; Total Number of Employees Exposed 63,333; Total Number of Female Employees Exposed 49,362 | ||||
STATUS IN FEDERAL AGENCIES:
ORGANIZATION
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REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
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REFERENCES:
CODEN
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REFERENCE
28ZPAK
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"Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku," Marhold, J.V., Institut Pro
Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha, Czechoslovakia, 1972
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ACEDAB
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Acta Endocrinologica, Supplementum (Copenhagen). (Periodica, Skolegade 12 E, DK-2500 Valby,
Denmark) No.1- 1948-
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ADCHAK
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Archives of Disease in Childhood. (British Medical Journal, POB 560B, Kennebunkport, ME
04046) V.1- 1926-
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AEPPAE
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Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.)
V.110-253, 1925-66. For publisher information, see NSAPCC.
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CLECAP
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Clinical Endocrinology (Oxford). (Blackwell Scientific Pub. Ltd., POB 88, Oxford, UK) V.1-
1972-
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EJEND*
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European journal of endocrinology (European journal of endocrinology, Bristol, UK :
BioScientifica Ltd.) V.130- 1994-
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FATOAO
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Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O
Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939-
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HBAMAK
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"Abdernalden's Handbuch der Biologischen Arbeitsmethoden." (Leipzig, Ger. Dem. Rep.)
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JPETAB
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Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E.
Preston St., Baltimore, MD 21202) V.1- 1909/10-
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JTEHD6
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Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW,
Washington, DC 20005) V.1- 1975/76-
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PSEBAA
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Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E.
First St., Duluth, MN 55802) V.1- 1903/04-
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TOXID9
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Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1-
1981-
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VCVN5*
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"Vrednie chemichescie veshestva. Neorganicheskie soedinenia elementov V-VII groopp" (Hazardous
substances. Inornanic substances containing V-VII group elements), Bandman A.L. et al.,
Chimia, 1989.
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