The Registry of Toxic Effects of Chemical Substances

Silane, dichloromethyl -

RTECS #: VV3500000

CAS #: 75-54-7

UPDATE: September 1997 MW: 115.04 MF: CH4Cl2Si


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. SKIN AND EYE IRRITATION DATA:
  3. ACUTE TOXICITY DATA:
  4. NIOSH DOCUMENTATION AND SURVEILLANCE:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. Dichloromethylsilane
  2. Monomethyldichlorosilane
  1. Methyl - dichlorsilan (Czech)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
eye
rabbit 		20 mg/24 hour moderate 85JCAE -,1218,1986
skin
rabbit 		2 mg/24 hour severe 85JCAE -,1218,1986


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
rat 		lethal concentration (50 percent kill): 300 ppm/4 hour N/R 85JCAE -,1218,1986
oral
rat 		lethal dose (50 percent kill): 2,830 µL/kg Eye: Lacrimation

Lung, Thorax, or Respiration: Other changes

Gastrointestinal: Other changes 		ATDAEI 12,572,1993


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: X3236;
Number of Industries 2;
Total Number of Facilities 10;
Number of Occupations 5;
Total Number of Employees Exposed 371;
Total Number of Female Employees Exposed 34


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY


REFERENCES:

CODEN
REFERENCE
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986
ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990-

RTECS Compound Description:
   Primary Irritant

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