The Registry of Toxic Effects of Chemical Substances

Silane

RTECS #: VV1400000

CAS #: 7803-62-5


UPDATE: November 2004 MW: 32.13 MF: H4Si


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. MUTATION DATA:
  3. ACUTE TOXICITY DATA:
  4. REVIEWS:
  5. STANDARDS AND REGULATIONS:
  6. NIOSH DOCUMENTATION AND SURVEILLANCE:
  7. STATUS IN FEDERAL AGENCIES:
  8. REFERENCES:

SYNONYMS:

  1. Flots 100SCO
  2. Monosilane
  3. Silicane
  1. Silicon tetrahydride
  2. Silicon tetrahydride (ACGIH)


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE
DOSE REFERENCE
mutation in microorganisms Salmonella typhimurium 1 pph (+/-enzymatic activation step) MUREAV 307,335,1994


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
inhalation
mouse
lowest published lethal concentration: 9,600 ppm/4 hour N/R AMRL** TR-72-62,1972
inhalation
rat
lethal concentration (50 percent kill): 9,600 ppm/4 hour N/R TXAPA9 42,417,1977


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM
DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 5 ppm DTLVS* TLV/BEI,2003


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE

Occupational Exposure Limit - AUSTRALIA time-weighted average 5 ppm (7 mg/m3), JAN1993
Occupational Exposure Limit - BELGIUM time-weighted average 5 ppm (6.6 mg/m3), JAN1993
Occupational Exposure Limit - DENMARK time-weighted average 0.5 ppm (0.7 mg/m3), JAN1999
Occupational Exposure Limit - FINLAND time-weighted average 0.5 ppm (0.7 mg/m3), short term exposure limit 1.5 ppm (2.0 mg/m3), JAN1999
Occupational Exposure Limit - FRANCE VME 5 ppm (7 mg/m3), JAN1999
Occupational Exposure Limit - JAPAN Occupational Exposure Limit( continuous) 100 ppm (130 mg/m3), JAN1999
Occupational Exposure Limit - NORWAY time-weighted average 0.5 ppm (0.7 mg/m3), JAN1999
Occupational Exposure Limit - THE NETHERLANDS MAC-TGG 0.7 mg/m3, 2003
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 0.5 ppm (0.67 mg/m3), short term exposure limit 1 ppm, SEP2000
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

time-weighted average 5 ppm
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
time-weighted average 5 ppm


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Level TO SILICON TETRAHYDRIDE-air 10 hour time-weighted average 5 ppm NIOSH* DHHS #92-100,1992
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 83770;
Number of Industries 44;
Total Number of Facilities 1,732;
Number of Occupations 41;
Total Number of Employees Exposed 33,190
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 83770;
Number of Industries 11;
Total Number of Facilities 510;
Number of Occupations 17;
Total Number of Employees Exposed 25,354;
Total Number of Female Employees Exposed 2,999


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY


REFERENCES:

CODEN
REFERENCE

AMRL** Aerospace Medical Research Laboratory Report. (Aerospace Technical Div., Air Force Systems Command, Wright-Patterson Air Force Base, OH 45433)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-
NIOSH* National Institute of Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda.
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959-

Used in the doping of solid-state devices and as a source of SILICON for semiconductors

RTECS Compound Description:
   Mutagen

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