RTECS:VS7175000 The Registry of Toxic Effects of Chemical Substances | CDC/NIOSH

The Registry of Toxic Effects of Chemical Substances

Selenious acid

RTECS #: VS7175000

CAS #: 7783-00-8

UPDATE: May 2004 MW: 128.98 MF: H₂O₃Se

NOTE:

TOXICITY DATA HAVE NOT BEEN EVALUATED. OMISSION OF A SUBSTANCE OR NOTATION DOES NOT IMPLY ANY RELIEF FROM REGULATORY RESPONSIBILITY.

TABLE OF CONTENTS:

SYNONYMS:

MUTATION DATA:

ACUTE TOXICITY DATA:

OTHER MULTIPLE DOSE DATA:

REVIEWS:

STANDARDS AND REGULATIONS:

NIOSH DOCUMENTATION AND SURVEILLANCE:

STATUS IN FEDERAL AGENCIES:

REFERENCES:

SYNONYMS:

RCRA waste number U204

Selenium dioxide

SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

MUTATION DATA AND REFERENCES:
SYSTEM TEST ROUTE/
ORGANISM/
TISSUE DOSE REFERENCE
cytogenetic analysis human lymphocyte 10 痠ol/L ESKGA2 26,99,1980
micronucleus test intraperitoneal
mouse 10 mg/kg/2 day- continuous MUREAV 367,233,1996

REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

TUMORIGENIC DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
N/R
N/R N/R N/R

ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
intraperitoneal
rat lowest published lethal dose: 10 mg/kg N/R NCNSA6 5,28,1953
intravenous
mouse lethal dose (50 percent kill): 11 mg/kg N/R CSLNX* NX#05656
oral
rat lowest published lethal dose: 25 mg/kg N/R NCNSA6 5,28,1953

OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/
ORGANISM DOSE
EFFECT

REFERENCE
intraperitoneal
rat lowest published toxic dose: 0.938 mg/kg/14 day- intermittent Blood: Changes in bone marrow not included in above

Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Other oxidoreductases JTEHD6 59,553,2000
subcutaneous
rabbit lowest published toxic dose: 4,800 痢/kg/14 day- intermittent Behavioral: Food intake (animal)

Blood: Changes in serum composition (e.g. TP, bilirubin, cholesterol)

Nutritional and Gross Metabolic: Weight loss or decreased weight gain NEZAAQ 14,9,1959

REVIEWS:
ORGANIZATION STANDARD
REFERENCE

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value time-weighted average 0.2 mg(Se)/m³ DTLVS* TLV/BEI,1999

STANDARDS AND REGULATIONS:
ORGANIZATION STANDARD
REFERENCE

Mine Safety and Health Administration (MSHA) STANDARD - air time-weighted average 0.2 mg(Se)/m³ DTLVS* 3,224,1971
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (General Industry) 8 hour time-weighted average 0.2 mg(Se)/m³ CFRGBR 29,1910.1000,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Construction) 8 hour time-weighted average 0.2 mg(Se)/m³ CFRGBR 29,1926.55,1994
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Shipyards) 8 hour time-weighted average 0.2 mg(Se)/m³ CFRGBR 29,1915.1000,1993
Occupational Safety and Health Administration (OSHA) Permissible Exposure Limit (Federal Contractors) 8 hour time-weighted average 0.2 mg(Se)/m³ CFRGBR 41,50-204.50,1994
Occupational Exposure Limit - ARAB Republic of Egypt time-weighted average 0.2 mg(Se)/m³, JAN1993
Occupational Exposure Limit - AUSTRALIA time-weighted average 0.2 mg(Se)/m³, JAN1993
Occupational Exposure Limit - AUSTRIA MAK 0.1 mg(Se)/m³, JAN1999
Occupational Exposure Limit - BELGIUM time-weighted average 0.2 mg(Se)/m³, JAN1993
Occupational Exposure Limit - DENMARK time-weighted average 0.1 mg(Se)/m³, JAN1999
Occupational Exposure Limit - FINLAND time-weighted average 0.1 mg(Se)/m³, short term exposure limit 0.3 mg(Se)/m³, JAN1999
Occupational Exposure Limit - GERMANY MAK 0.1 mg(Se)/m³, JAN1999
Occupational Exposure Limit - HUNGARY short term exposure limit 0.1 mg(Se)/m³, JAN1993
Occupational Exposure Limit - NORWAY time-weighted average 0.1 mg(Se)/m³, JAN1999
Occupational Exposure Limit - THE PHILIPPINES time-weighted average 0.2 mg(Se)/m³, JAN1993
Occupational Exposure Limit - POLAND MAC(time-weighted average) 0.1 mg(Se)/m³, JAN1993
Occupational Exposure Limit - SWEDEN NGV 0.1 mg(Se)/m³, JAN1999
Occupational Exposure Limit - SWITZERLAND MAK- week 0.1 mg(Se)/m³, JAN1999
Occupational Exposure Limit - TURKEY time-weighted average 0.2 mg(Se)/m³, JAN1993
Occupational Exposure Limit - UNITED KINGDOM time-weighted average 0.1 mg(Se)/m³, SEP2000
Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value;

time-weighted average 0.2 mg(Se)/m³
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
time-weighted average 0.2 mg(Se)/m³

NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION STANDARD or SURVEY
REFERENCE

National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: 84466;
Number of Industries 4;
Total Number of Facilities 345;
Number of Occupations 3;
Total Number of Employees Exposed 1,177
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: 84466;
Number of Industries 17;
Total Number of Facilities 1,294;
Number of Occupations 17;
Total Number of Employees Exposed 7,593;
Total Number of Female Employees Exposed 1,866

STATUS IN FEDERAL AGENCIES:
ORGANIZATION
REFERENCE

EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as oxidizing agent
EPA TSCA Section 8(d) unpublished health/safety studies
On EPA IRIS database
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001

REFERENCES:
CODEN
REFERENCE

CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402)
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010)
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
ESKGA2 Eisei Kagaku. Hygienic Chemistry. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1953-
JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76-
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964-
NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC)
NEZAAQ Nippon Eiseigaku Zasshi. Japanese Journal of Hygiene. (Nippon Eisei Gakkai, c/o Kyoto Daigaku Igakubu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.1- 1946-

Used as oxidizing agent

NIOSH PROFILE (SELENIUM AND ITS COMPOUND), SRC, 4/78

RTECS Compound Description:
Agricultural Chemical
Mutagen

ALT CAS #: 11140-60-6
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