The Registry of Toxic Effects of Chemical Substances
Rosin |
UPDATE: November 2004 | MW: N/R | MF: N/R |
SYNONYMS:
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SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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N/R |
N/R
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N/R
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N/R
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MUTATION DATA AND REFERENCES:
SYSTEM TEST
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ROUTE/ | ORGANISM/ TISSUE
DOSE
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REFERENCE
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N/R
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N/R
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N/R
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N/R
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REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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N/R |
N/R
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N/R
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N/R
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TUMORIGENIC DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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N/R |
N/R
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N/R
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N/R
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ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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inhalation | rat
lethal concentration (50 percent kill): 110 mg/m3
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Behavioral: Somnolence (general depressed activity) | Cardiac: Pulse rate decreased with fall in BP Lung, Thorax, or Respiration: Respiratory depression
VCVPS* -,294,1998
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oral | mouse
lethal dose (50 percent kill): 2.2 mg/kg
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Behavioral: Somnolence (general depressed activity) | Cardiac: Pulse rate decreased with fall in BP Lung, Thorax, or Respiration: Respiratory depression
VCVPS* -,294,1998
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oral | rat
lethal dose (50 percent kill): 3.0 mg/kg
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Brain and Coverings: Other degenerative changes | Liver: Other changes Biochemical: Metabolism (intermediary): Other
VCVPS* -,294,1998
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OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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oral | rat
lowest published toxic dose: 175 gm/kg/50 day- intermittent
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Lung, Thorax, or Respiration: Dyspnea | Liver: Hepatitis (hepatocellular necrosis), zonal Liver: Fatty liver degeneration
VCVPS* -,294,1998
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oral | rabbit
lowest published toxic dose: 455 gm/kg/13 week- intermittent
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Liver: Other changes | Blood: Thrombocytopenia Nutritional and Gross Metabolic: Changes in: K
VCVPS* -,294,1998
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REVIEWS:
ORGANIZATION
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STANDARD
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REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
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reduce to as low as possible
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DTLVS* TLV/BEI,1999
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American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
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time-weighted average L (sen)
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DTLVS* TLV/BEI,2003
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STANDARDS AND REGULATIONS:
ORGANIZATION
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STANDARD
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REFERENCE
Occupational Exposure Limit - THE NETHERLANDS
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MAC-TGG 0.1 mg/m3, 2003
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NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION
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STANDARD or SURVEY
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REFERENCE
National Occupational Exposure Survey 1983
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National Occupational Exposure Survey 1983: Hazard Code: X2732; | Number of Industries 1; Total Number of Facilities 511; Number of Occupations 1; Total Number of Employees Exposed 511
National Occupational Exposure Survey 1983
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National Occupational Exposure Survey 1983: Hazard Code: X6806; | Number of Industries 9; Total Number of Facilities 758; Number of Occupations 14; Total Number of Employees Exposed 8,324; Total Number of Female Employees Exposed 2,339
National Occupational Exposure Survey 1983
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National Occupational Exposure Survey 1983: Hazard Code: 80164; |
Number of Industries 199; Total Number of Facilities 27,401; Number of Occupations 133; Total Number of Employees Exposed 566,016; Total Number of Female Employees Exposed 212,612 |
STATUS IN FEDERAL AGENCIES:
ORGANIZATION
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REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
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REFERENCES:
CODEN
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REFERENCE
DTLVS*
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The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by
American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
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VCVPS*
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"Vrednie chemichescie veshestva. Prirodnie organicheskie soedinenia" (Hazardous substances.
Nature products.) Volkova N.V. et al., Sankt-Peterburg, 1998.
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