The Registry of Toxic Effects of Chemical Substances

Pyridine, 2 - (1 - methyl - 2 - (4 - phenoxyphenoxy) ethoxy) -

RTECS #: UT5804000

CAS #: 95737-68-1

UPDATE: May 2005 MW: 321.40 MF: C20H19NO3


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. ACUTE TOXICITY DATA:
  3. OTHER MULTIPLE DOSE DATA:
  4. STANDARDS AND REGULATIONS:
  5. REFERENCES:

SYNONYMS:

  1. 4 - Phenoxyphenyl (RS) - 2 - (2 - pyridyloxy) propyl ether
  2. 2 - (1 - Methyl - 2 - (4 - phenoxyphenoxy) ethoxy) pyridine
  3. Pyriproxyfen
  1. S 31183
  2. S 9138
  3. SK 591


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
rat 		lethal dose (50 percent kill): >2,000 mg/kg N/R FEREAC 68,11093,2003
skin
rat 		lethal dose (50 percent kill): >2 gm/kg N/R PEMNDP 9,745,1991


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
inhalation
rat 		lowest published toxic concentration: 1,000 gm/m3/28 day- intermittent Gastrointestinal: Changes in structure or function of salivary glands

Nutritional and Gross Metabolic: Weight loss or decreased weight gain

Biochemical: Enzyme inhibition, induction, or change in blood or tissue levels: Dehydrogenases 		FEREAC 68,10972,2003
inhalation
rat 		lowest published toxic concentration: 1,000 gm/m3/28 day- intermittent Gastrointestinal: Changes in structure or function of salivary glands FEREAC 68,10972,2003
oral
dog 		lowest published toxic dose: 27,000 mg/kg/90 day- continuous Liver: Changes in liver weight FEREAC 68,10972,2003
oral
mouse 		lowest published toxic dose: 75,429 mg/kg/90 day- intermittent Liver: Changes in liver weight

Kidney, Ureter, and Bladder: Other changes

Blood: Other changes 		FEREAC 67,55150,2002
oral
mouse 		lowest published toxic dose: 75,429 mg/kg/90 day- continuous Liver: Changes in liver weight

Kidney, Ureter, and Bladder: Other changes

Nutritional and Gross Metabolic: Weight loss or decreased weight gain 		FEREAC 68,10972,2003
oral
mouse 		lowest published toxic dose: 86,751 mg/kg/90 day- continuous Liver: Changes in liver weight

Kidney, Ureter, and Bladder: Other changes

Blood: Changes in erythrocyte (RBC) count 		FEREAC 68,10972,2003
oral
rat 		lowest published toxic dose: 10,601.1 mg/kg/90 day- continuous Liver: Changes in liver weight

Blood: Changes in erythrocyte (RBC) count

Biochemical: Metabolism (intermediary): Lipids including transport 		FEREAC 68,10972,2003
oral
rat 		lowest published toxic dose: 12,715.2 mg/kg/90 day- continuous Blood: Other changes FEREAC 68,10972,2003


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES: Active registration RBREV* -,390,1998


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
N/R N/R N/R


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
N/R


REFERENCES:

CODEN
REFERENCE
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968-
RBREV* Status of Pesticides in Registration, Reregistration, and Special Review (Rainbow Report), Special Review and Reregistration Division Office of Pesticide Programs U.S. Environmental Protection Agency, 401 M. Street, S.W., Washington, D.C. 20460, Spring 1998

RTECS Compound Description:
   Agricultural Chemical

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