The Registry of Toxic Effects of Chemical Substances
2 - Propenoic acid, 2 - cyano - , ethyl ester |
UPDATE: May 2004 | MW: 125.14 | MF: C6H7NO2 |
SYNONYMS:
|
|
|
SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
skin | rabbit
500 µL/24 hour
|
mild
|
IJTOFN 16(Suppl 2),30,1997
|
|
MUTATION DATA AND REFERENCES:
SYSTEM TEST
|
ROUTE/ | ORGANISM/ TISSUE
DOSE
|
REFERENCE
|
N/R
|
N/R
|
N/R
|
N/R
|
|
REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
|
TUMORIGENIC DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
|
ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
oral | rat
lethal dose (50 percent kill): >5 mL/kg
|
Behavioral: Somnolence (general depressed activity) | Gastrointestinal: Other changes
IJTOFN 16(Suppl 2),30,1997
|
|
OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
|
| EFFECT
REFERENCE
|
N/R |
N/R
|
N/R
|
N/R
|
|
REVIEWS:
ORGANIZATION
|
STANDARD
|
|
REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
|
time-weighted average 0.2 ppm
|
DTLVS* TLV/BEI,2003
|
|
STANDARDS AND REGULATIONS:
ORGANIZATION
|
STANDARD
|
|
REFERENCE
Occupational Exposure Limit - AUSTRIA
|
MAK 2 ppm (9 mg/m3), JAN1999
|
|
NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION
|
STANDARD or SURVEY
|
|
REFERENCE
N/R
|
N/R
|
N/R
|
|
STATUS IN FEDERAL AGENCIES:
ORGANIZATION
|
|
REFERENCE
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
|
OSHA ANALYTICAL METHOD #55
|
|
REFERENCES:
CODEN
|
|
REFERENCE
DTLVS*
|
The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by
American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
|
IJTOFN
|
International Journal of Toxicology. (Taylor & Francis, 47 Runway Rd., Suite g, Levittown, PA
19057) V.16- 1997-
|
|