The Registry of Toxic Effects of Chemical Substances
Propene RTECS #: UC6740000
CAS #: 115-07-1
The Registry of Toxic Effects of Chemical Substances
Propene |
| UPDATE: November 2004 | MW: 42.09 | MF: C3H6 |
SYNONYMS:
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SKIN AND EYE IRRITATION DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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N/R |
N/R
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N/R
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N/R
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MUTATION DATA AND REFERENCES:
SYSTEM TEST
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ROUTE/ | ORGANISM/ TISSUE
DOSE
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REFERENCE
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N/R
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N/R
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N/R
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N/R
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REPRODUCTIVE EFFECTS DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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N/R |
N/R
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N/R
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N/R
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TUMORIGENIC DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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inhalation | mouse
lowest published toxic concentration: 865,200 mg/kg/103 week- continuous
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Tumorigenic: Equivocal tumorigenic agent by RTECS criteria | Reproductive: Tumorigenic effects: Uterine tumors
NTIS** PB86-145521/AS
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inhalation | rat
lowest published toxic concentration: 154,500 mg/kg/103 week- continuous
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Tumorigenic: Neoplastic by RTECS criteria | Olfaction: Tumors
NTIS** PB86-145521/AS
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inhalation | rat
lowest published toxic concentration: 128,750 mg/kg/103 week- continuous
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Tumorigenic: Neoplastic by RTECS criteria | Olfaction: Tumors
NTIS** PB86-145521/AS
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ACUTE TOXICITY DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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inhalation | rat
lethal concentration : >86 gm/m3/4 hour
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N/R
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IMEMDT 60,161,1994
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OTHER MULTIPLE DOSE DATA AND REFERENCES:
ROUTE/ | ORGANISM
DOSE
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| EFFECT
REFERENCE
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inhalation | mouse
lowest published toxic concentration: 1,250 ppm/6 hour/14 week- intermittent
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Related to Chronic Data: Death in the "MULTIPLE DOSE" data type field
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NTPTR* NTP-TR-272,1985
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inhalation | mouse
lowest published toxic concentration: 309,000 mg/kg/103 week- intermittent
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Lung, Thorax, or Respiration: Bronchogenic carcinoma | Tumorigenic: Active as anti-cancer agent
NTIS** PB86-145521/AS
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inhalation | rat
lowest published toxic concentration: 5,000 ppm/6 hour/2 year- intermittent
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Olfaction: Other olfaction effects
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TXAPA9 76,288,1984
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REVIEWS:
ORGANIZATION
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STANDARD
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REFERENCE
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
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Simple asphyxiant ( day)
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DTLVS* TLV/BEI,2003
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American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value
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Not Classifiable as a Human Carcinogen
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DTLVS* TLV/BEI,2003
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International Agency for Research on Cancer (IARC) Cancer Review
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Human No Adequate Data
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IMEMDT 19,213,1979
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International Agency for Research on Cancer (IARC) Cancer Review
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Animal No Adequate Data
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IMEMDT 19,213,1979
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International Agency for Research on Cancer (IARC) Cancer Review
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Animal Inadequate Evidence
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IMEMDT 60,161,1994
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International Agency for Research on Cancer (IARC) Cancer Review
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Human Inadequate Evidence
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IMEMDT 60,161,1994
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International Agency for Research on Cancer (IARC) Cancer Review
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Group 3
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IMEMDT 60,161,1994
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TOXICOLOGY REVIEW
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MUREAV 566,21,2004
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TOXICOLOGY REVIEW
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MUREAV 543,201,2003
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STANDARDS AND REGULATIONS:
ORGANIZATION
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STANDARD
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REFERENCE
Occupational Exposure Limit - AUSTRALIA
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Asphyxiant, JAN1993
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Occupational Exposure Limit - BELGIUM
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Asphyxiant, JAN1993
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Occupational Exposure Limit - HUNGARY
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Asphyxiant, JAN1993
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Occupational Exposure Limit - RUSSIA
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short term exposure limit 100 mg/m3, JAN1993
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Occupational Exposure Limit - SWITZERLAND
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MAK- week 10000 ppm (17500 mg/m3), JAN1999
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Occupational Exposure Limit - UNITED KINGDOM
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Asphyxiant, SEP2000
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Occupational Exposure Limit - THE NETHERLANDS
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MAC-TGG 900 mg/m3, 2003
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Occupational Exposure Limit IN ARGENTINA, BULGARIA, COLOMBIA, JORDAN, KOREA
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American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value; | Not Classifiable as a Human Carcinogen
Occupational Exposure Limit IN NEW ZEALAND, SINGAPORE, VIETNAM
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American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value |
Not Classifiable as a Human Carcinogen | |||||||||||
NIOSH DOCUMENTATION AND SURVEILLANCE:
ORGANIZATION
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STANDARD or SURVEY
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REFERENCE
National Occupational Hazard Survey 1974
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National Occupational Hazard Survey 1974: Hazard Code: 63495; | Number of Industries 16; Total Number of Facilities 493; Number of Occupations 32; Total Number of Employees Exposed 7,150
National Occupational Exposure Survey 1983
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National Occupational Exposure Survey 1983: Hazard Code: 63495 |
 ;Number of Industries 7; Total Number of Facilities 162; Number of Occupations 25; Total Number of Employees Exposed 7,305; Total Number of Female Employees Exposed 975 | ||||
STATUS IN FEDERAL AGENCIES:
ORGANIZATION
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REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
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Used in production of fabricated polymers, fibers and solvents
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EPA TSCA Section 8(d) unpublished health/safety studies
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EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001
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NCI Carcinogenesis Studies (inhal);no evidence:mouse,rat
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REFERENCES:
CODEN
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REFERENCE
DTLVS*
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The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by
American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996
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IMEMDT
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IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications
Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972-
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MUREAV
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Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1-
1964-
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NTIS**
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National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse
for Scientific & Technical Information.
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NTPTR*
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National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709)
No.206-
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TXAPA9
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Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)
V.1- 1959-
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