The Registry of Toxic Effects of Chemical Substances

Pivalic acid

RTECS #: TO7700000

CAS #: 75-98-9

UPDATE: October 1997 MW: 102.15 MF: C5H10O2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. TUMORIGENIC DATA:
  3. ACUTE TOXICITY DATA:
  4. NIOSH DOCUMENTATION AND SURVEILLANCE:
  5. STATUS IN FEDERAL AGENCIES:
  6. REFERENCES:

SYNONYMS:

  1. Acetic acid, trimethyl -
  2. 2,2 - Dimethylpropanoic acid
  3. alpha,alpha - Dimethylpropionic acid
  4. 2,2 - Dimethylpropionic acid
  5. Neopentanoic acid
  1. tert - Pentanoic acid
  2. Kyselina 2,2 - dimethylpropionova (Czech)
  3. Kyselina pivalova (Czech)
  4. Propionic acid, 2,2 - dimethyl -
  5. Trimethylacetic acid


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
skin
mouse 		lowest published toxic dose: 188 mg/kg/47 week- intermittent Tumorigenic: Equivocal tumorigenic agent by RTECS criteria

Lung, Thorax, or Respiration: Tumors

Skin and Appendages: Tumors 		CALEDQ 17,61,1982


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
rat 		lethal dose (50 percent kill): 900 mg/kg N/R 37ASAA 4,863,1978
skin
rat 		lethal dose (50 percent kill): 1,900 mg/kg N/R 37ASAA 4,863,1978


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
National Occupational Hazard Survey 1974 National Occupational Hazard Survey 1974: Hazard Code: A1178;
Number of Industries 1;
Total Number of Facilities 33;
Number of Occupations 2;
Total Number of Employees Exposed 1,683
National Occupational Exposure Survey 1983 National Occupational Exposure Survey 1983: Hazard Code: A1178;
Number of Industries 1;
Total Number of Facilities 16;
Number of Occupations 1;
Total Number of Employees Exposed 1,462;
Total Number of Female Employees Exposed 996


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
37ASAA "Kirk-Othmer Encyclopedia of Chemical Technology," 3rd ed., Grayson, M., and D. Eckroth, eds., New York, John Wiley & Sons, Inc., 1978
CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975-

RTECS Compound Description:
   Tumorigen

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