The Registry of Toxic Effects of Chemical Substances

Picolinic acid, 3,6 - dichloro -

RTECS #: TJ7550700

CAS #: 1702-17-6

UPDATE: November 2004 MW: 192.00 MF: C6H3Cl2NO2


NOTE:

TABLE OF CONTENTS:
  1. SYNONYMS:
  2. REPRODUCTIVE EFFECTS DATA:
  3. ACUTE TOXICITY DATA:
  4. OTHER MULTIPLE DOSE DATA:
  5. STANDARDS AND REGULATIONS:
  6. STATUS IN FEDERAL AGENCIES:
  7. REFERENCES:

SYNONYMS:

  1. Acide 3,6 - dcp
  2. Acide 3,6 - dichloropicolinique (French)
  3. Clopyralid
  4. 3,6 - Dichloropicolinic acid
  5. 3,6 - Dichloro - 2 - pyridinecarboxylic acid
  6. Dowco 290
  7. Format
  1. Kyselina 3,6 - dichlorpikolinova (Czech)
  2. Lontrel
  3. Lontrel 3
  4. Matrigon
  5. 2 - Pyridinecarboxylic acid, 3,6 - dichloro - (9CI)
  6. Reclaim
  7. XRM 3972


SKIN AND EYE IRRITATION DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


MUTATION DATA AND REFERENCES:

SYSTEM TEST ROUTE/
ORGANISM/
TISSUE 		DOSE REFERENCE
N/R N/R N/R N/R


REPRODUCTIVE EFFECTS DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
rat 		lowest published toxic dose: 150 mg/kg (6-15 day pregnant) Reproductive: Specific developmental abnormalities: Musculoskeletal system FAATDF 4,91,1984
unreported route
mammal (species unspecified) 		lowest published toxic dose: 1,500 mg/kg (multigenerations) Reproductive: Effects on newborn: Growth statistics (e.g., reduced weight gain) FEREAC 65,57953,2000


TUMORIGENIC DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
N/R
 N/R N/R N/R


ACUTE TOXICITY DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
intraperitoneal
rat 		lethal dose (50 percent kill): 900 mg/kg N/R DEVEAA 31,387,1977
oral
duck 		lethal dose (50 percent kill): 1,465 mg/kg N/R PEMNDP 9,182,1991
oral
mouse 		lethal dose (50 percent kill): >5 gm/kg N/R DEVEAA 31,387,1977
oral
rat 		lethal dose (50 percent kill): 4,300 mg/kg N/R 85JFAN A433,1985
skin
rabbit 		lethal dose (50 percent kill): >2 gm/kg N/R DEVEAA 31,387,1977


OTHER MULTIPLE DOSE DATA AND REFERENCES:

ROUTE/
ORGANISM 		DOSE
EFFECT

 REFERENCE
oral
mouse 		lowest published toxic dose: 450,000 mg/kg/90 day- intermittent Nutritional and Gross Metabolic: Weight loss or decreased weight gain FEREAC 67,60152,2002


REVIEWS:

ORGANIZATION STANDARD
REFERENCE
N/R N/R N/R


STANDARDS AND REGULATIONS:

ORGANIZATION STANDARD
REFERENCE
Environmental Protection Agency (EPA) Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) 1998 STATUS OF PESTICIDES: Active registration RBREV* -,360,1998


NIOSH DOCUMENTATION AND SURVEILLANCE:

ORGANIZATION STANDARD or SURVEY
REFERENCE
N/R N/R N/R


STATUS IN FEDERAL AGENCIES:

ORGANIZATION
REFERENCE
EPA TSCA Section 8(b) CHEMICAL INVENTORY
Used as a systemic post-emergence herbicide
On EPA IRIS database
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JANUARY 2001


REFERENCES:

CODEN
REFERENCE
85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc. of Chemistry, 1983-86
DEVEAA Defense des Vegetaux. (Federation Nationale des Groupements de Protection des Cultures, 149, rue de Bercy, 75595 Paris Cedex, 12, France) V.1- 1947-
FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1-40, 1981-97. For publisher information, see TOSCF2
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936-
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968-
RBREV* Status of Pesticides in Registration, Reregistration, and Special Review (Rainbow Report), Special Review and Reregistration Division Office of Pesticide Programs U.S. Environmental Protection Agency, 401 M. Street, S.W., Washington, D.C. 20460, Spring 1998

Used as a systemic post-emergence herbicide

RTECS Compound Description:
   Agricultural Chemical
   Reproductive Effector

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